Save on Science and the Media

			Please open the online version of this message if the HTML is not correctly displayed.
		20% off this new title. Enter promotional code 94619 at checkout to receive your discount.
			Science and the Media: Delgado's Brave Bulls and the Ethics of Scientific Disclosure Peter J. Snyder, Linda C. Mayes, and Dennis H. Spencer Now Available, Hardcover, 272 pp. List Price: $ 49.95 USD Discount Price: $ 39.96 USD Of great utility for every scientist faced with publicizing their discoveries via the media, this book addresses questions of responsibility for the balance and accuracy of scientific reporting, and attempts to be a guide for the scientist in their quest to inform the general public about their research in honest, truthful, and still interesting ways. Read more... *The special offers made in this email are intended for our direct customers, and are not applicable to resellers or other third parties. Cannot be combined with other offers. Discount offer expires December 31, 2009. Enter promotional code 94619 at checkout to redeem your discount.  About This Title Provides a compelling overview and analysis of the difficulties of dealing with mass media and collects tips and solutions. Includes case studies from the experience of a number of high profile contributors from different fields Provides an easy to read, carefully selected and synthesized overview well suited to teaching and as further reading source in respective classes Includes a famous movie from Jose Delgado that shows his attempts in the 60s to demonstrate "remote control" of a bull  Contents 1 Snyder, Mayes: Introduction: The Ethics of Scientific Disclosure 2 John Warner, History of Medicine, Yale: Medicine, Media and the Dramaturgy of Biomedical Research: Historical Perspectives 3 Snyder: Delgado's Brave Bulls: The Marketing of a Seductive Idea and a Lesson for Contemporary Biomedical Science 4 Dennis Spencer, Neurosurgery, Yale: Adrenal Transplantation for Parkinson's Disease 5 Peter Fonagy, University College London: The Use of SSRIs in the Treatment of Childhood Depression: A Scientific Dialectic 6 David Smith, Yale Interdisciplinary Bioethics Project, Aaron Klink, Duke University School of Divinity, and Julius Landwirth, Interdisciplinary Center for Bioethics, Yale: Media Coverage of Stem Cell Research 7 Jerome Kassirer, Tufts: Medicine's Obsession with Disclosure of Financial Conflicts: Fixing the Wrong Problem 8 Declan Doogan, Pfizer: In Support of Industry-Sponsored Clinical Research 9 The Very Reverenc Wesley Carr, Romsey, UK: Prevailing Truth: The Interface Between Religion and Science 10 Patricia Shipman, Dept Anthropology, Pennsylvania State University: Science Meets Fundamentalist Religion 11 Ruth Katz, School of Public Health and Health Services, George Washington University: Uneasy Alliance: The Intersection of Government Science, Politics and Policymaking 12 Robert Levine, Yale Center for Bioethics: On The Relations Between Scientists and Journalist: Reflections by an Ethicist 13 Laura Spinnney, Science Journalist, London: Don't Shoot the Messenger 14 Harry McConnell, Ashley Pardy, Australia: Future Trends in Medical Research Publishing 15 Peter Snyder, Linda Mayes, Dennis Spencer: Conclusion: The Ethics of Scientific Disclosure
			Data Protection Notice This e-mail has been sent to manojhind2001us1.stemcell@blogger.com from Elsevier Science & Technology Books, 30 Corporate Drive, 4th Floor, Burlington, MA 01803, United States, using Email Reaction's Technology and Platform. To ensure delivery to your inbox (not bulk or junk folders), please add lifescience.books@mail.elsevier-alerts.com to your address book. You are receiving this e-mail because you have either purchased a title published by Elsevier Science and Technology Books, or expressed interest in Life Science books. If you no longer wish to receive marketing messages on Life Science books, you can Unsubscribe here. Copyright © 2009 Elsevier Inc. All rights reserved.  Read the Elsevier S&T Books Privacy Policy. Read the Email Reaction Privacy Policy.
			Special Offers - The special offers made in this email are intended for our direct customers, and are not applicable to resellers or other third parties.

Mr Valluru: Industry subscription

Please open the online version of this message if the HTML is not correctly displayed. www.drugdiscoverytoday.com Drug Discovery Today: Complimentary Digital Copies   Key review areas for 2009: • Therapeutics • Virtual Screening • Molecular biology • Bioinformatics • Receptors and channels • Medicinal chemistry • Spectroscopy • Drug delivery • Cell/tissue culture • Medicinal chemistry • Gene expression analysis • Lab automation/HTS   Dear Mr Valluru, Drug Discovery Today is offering you the chance to register for a year's worth of complimentary digital copies. Packed full of the best coverage of rapid scientific developments, opinionated editorials, interviews and business trends, Drug Discovery Today is one of the most cited review journals in the field of drug discovery, with an impact factor of 7.7. To see a sample copy of our digital edition, simply click here. Drug Discovery Today publishes reviews covering the whole of the preclinical drug discovery process, from target identification and validation to candidate selection. The reviews are at the cutting edge of the science underpinning drug discovery, and the translation of these sciences to therapies. To sign up, simply go to: http://www.subscription.co.uk/cc/ddt/0085 To ensure you receive the next copy of Drug Discovery Today for FREE, you need to register by 27 March 2009. I look forward to hearing from you. Best Regards, Steve Carney Editor Drug Discovery Today www.drugdiscoverytoday.com Data Protection Notice This e-mail has been sent to manojhind2001us1.stemcell@blogger.com from Elsevier Ltd., The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, registered in England with registered number 1982084, using Email Reaction's technology and platform. To ensure delivery to your inbox (not bulk or junk folders), please click here to add our address to your safe senders list. You are receiving this e-mail because you are a registered user of ScienceDirect® and have consented to receive information about related products. If you do not wish to receive general marketing messages from Elsevier Drug Discovery Journals, you can visit this page to Unsubscribe, enter your email address, and press the submit button and you will be unsubscribed. To update your ScienceDirect profile please go to the ScienceDirect website, login with your username and password and amend your preferences. Elsevier respects your privacy and does not disclose, sell or rent your personal information to any non-affiliated third parties without your consent, except as may be stated in the Elsevier Privacy Policy. Please visit this page to see Email Reaction's Privacy Policy. For all enquiries, problems or suggestions regarding this service, please contact: ddt@drugdiscoverytoday.com. Copyright © 2009 Elsevier Ltd. all rights reserved. ScienceDirect® is a registered trademark of Elsevier B.V.

Nature Clinical Practice Rheumatology - Table of Contents alert Volume 5 Issue 3

NATURE CLINICAL PRACTICE RHEUMATOLOGY

March 2009 Volume 5 Number 3

Visit Nature Clinical Practice Rheumatology online to browse the journal.

Now available at http://links.ealert.nature.com/ctt?kn=40&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

"Officially endorsed by the Asia Pacific League of Associations for
Rheumatology"

================ Important information - please read ================

Note: Starting with the April 2009 e-Alert, Nature Clinical Practice
Rheumatology will change its name to Nature Reviews Rheumatology. No
action is required on your part; you will continue to receive this
e-Alert each month. However, in compliance with our data protection
practices, we need to inform you that the sender's email address will
change from NCP_Rheumatology@ealert.nature.com to
Nature_Reviews_Rheumatology@ealert.nature.com

=====================================================================

In April 2009 Nature Clinical Practice Rheumatology will become Nature
Reviews Rheumatology, with a new look and additional content.

For more information visit:
http://links.ealert.nature.com/ctt?kn=10&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

=====================================================================

----------------------
EDITORIAL
----------------------
Available therapeutic options following failure of a first anti-TNF
agent
Alan J Silman
http://links.ealert.nature.com/ctt?kn=79&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
RESEARCH HIGHLIGHTS
----------------------
Successful targeting of mesangial cells using immunoliposomes
http://links.ealert.nature.com/ctt?kn=57&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Skin involvement does not predict severe complications of systemic
sclerosis
http://links.ealert.nature.com/ctt?kn=1&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Hypoxia enhances production of functional cartilage from stem cells
http://links.ealert.nature.com/ctt?kn=81&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

New strategies have more impact than drug choice on improvements in RA
management
http://links.ealert.nature.com/ctt?kn=11&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Bortezomib improves arthritis in a mouse model
http://links.ealert.nature.com/ctt?kn=64&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Respiratory ciliary function is impaired in Wegener's granulomatosis
http://links.ealert.nature.com/ctt?kn=77&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Cardiotrophin-1 signaling essential for normal mouse bone resorption
and formation
http://links.ealert.nature.com/ctt?kn=69&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

In brief
http://links.ealert.nature.com/ctt?kn=42&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
GUIDELINES SUMMARY
----------------------
Pharmacologic therapy to reduce fracture risk: comment on the clinical
practice guidelines of the ACP
E Michael Lewiecki
http://links.ealert.nature.com/ctt?kn=45&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
PRACTICE POINTS
----------------------
Is arthroscopic surgery a beneficial treatment for knee osteoarthritis?
Richard W Nutton
http://links.ealert.nature.com/ctt?kn=17&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Are static resting wrist splints beneficial in early RA?
Theodora PM Vliet Vlieland
http://links.ealert.nature.com/ctt?kn=12&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
CLINICAL ADVANCES
----------------------
How do the efficacy and safety of abatacept and infliximab compare in
the treatment of active RA?
Peter C Taylor
http://links.ealert.nature.com/ctt?kn=39&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Is tocilizumab in combination with traditional DMARDs safe and
effective for patients with active RA?
Eugen Feist and Gerd-R Burmester
http://links.ealert.nature.com/ctt?kn=38&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Is spleen tyrosine kinase inhibition an effective therapy for patients
with RA?
Axel J Hueber and Iain B McInnes
http://links.ealert.nature.com/ctt?kn=80&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

A new 5-lipoxygenase inhibitor seems to be safe and effective for the
treatment of osteoarthritis
Frances MK Williams and Tim D Spector
http://links.ealert.nature.com/ctt?kn=83&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Cerotlizumab pegol-what role does this new TNF inhibitor have in
the treatment of RA?
Daniel E Furst
http://links.ealert.nature.com/ctt?kn=21&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
VIEWPOINT
----------------------
Time for new outcome measures in hand osteoarthritis?
Emmanuel Maheu and Francis Berenbaum
http://links.ealert.nature.com/ctt?kn=26&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
REVIEWS
----------------------
Cardiac manifestations of neonatal lupus erythematosus: guidelines to
management, integrating clues from the bench and bedside
Jill P Buyon, Robert M Clancy and Deborah M Friedman
http://links.ealert.nature.com/ctt?kn=73&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

Imaging the painful osteoarthritic knee joint: what have we learned?
Claire YJ Wenham and Philip G Conaghan
http://links.ealert.nature.com/ctt?kn=24&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

New approaches for managing antiphospholipid syndrome
Doruk Erkan and Michael D Lockshin
http://links.ealert.nature.com/ctt?kn=3&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
CASE STUDY
----------------------
Clinical and radiographic response to a local infliximab injection in
a patient with chronic sacroiliitis
Finbar D O'Shea, Nigil Haroon, David C Salonen and Robert D Inman
http://links.ealert.nature.com/ctt?kn=28&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

----------------------
ERRATUM
----------------------
Potential new drug targets for osteoporosis
Chad Deal
http://links.ealert.nature.com/ctt?kn=51&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

=====================================================================

Lymphocytes Return Home

Immunology & Cell Biology is proud to bring you Lymphocytes Return
Home - a focus that brings together a collection of articles
representing our current understanding of how numerous cell types can
return to the thymus. Accompanying this focus is a special feature
dealing with the nature and possible functional consequences of
cellular traffic, both lymphoid and myeloid, back to the primary
lymphoid organs.

Take advantage of this limited time offer today!
Lymphocytes Return Home
http://links.ealert.nature.com/ctt?kn=53&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0

=====================================================================

You have been sent this Table of Contents Alert because you have opted
in to receive it. You can change or discontinue your e-mail alerts at
any time, by modifying your preferences on your nature.com account at:
http://links.ealert.nature.com/ctt?kn=27&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
(You will need to log in to be recognised as a nature.com registrant).

For further technical assistance, please contact our registration department:
registration@nature.com

For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com

For other enquiries, please contact our customer feedback department:
feedback@nature.com

Nature Publishing Group | 75 Varick Street, 9th Floor | New York |
NY 10013-1917 | USA

Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne -
San Diego - San Francisco - Washington - New York - Boston

=====================================================================

Latest PhD Studentships - 3 March 2009

Welcome to the FindAPhD weekly Newsletter. Listed below are the latest research projects to be advertised on FindAPhD.com.

Ghent University
Intracellular compartmentalisation of the signal transduction of 5-HT4 receptors in cardiac and gastrointestinal tissue

Medical Research Council
Mechanisms of Synaptic Recovery in Mouse Models Neurodegeneration

Imperial College London
Engineering Doctorate Scheme in Nuclear Engineering

University of Canterbury
Nonlinear dynamics and stability of piezoelectric microbeam arrays with applications to scanning force microscopy

University of Leicester
Study of protracted pulmonary bacterial infection in COPD.

University of Manchester
Autonomic Workload Management

University of Manchester
Autonomic Computing in Large-Scale Distributed Systems

University of Manchester
Analysis and control of hybrid dynamical systems. Application to switched control systems.

University of Manchester
Security and QoS in Mobile Ad Hoc Networks

University of Manchester
Robust formal semantics for natural language

University of Manchester
Quality-Driven, Cost-Effective Query Processing in Transient Dataspaces

University of Manchester
Protocol Implementation Using Model Based Design

University of Manchester
Protecting Consumers' Privacy in Digital Right Management

University of Manchester
Probability collectives for partially separable problems

University of Manchester
Perceptual Computing and Modelling

Many more projects have been added this week! Click here to view them all!

Kind regards,

The FindAPhD.com Team

---

Thinking of a Masters degree instead?
FindAMasters.com lists 1000s of Masters in all subjects!

---

Please click here if you would like to unsubscribe from the FindAPhD.com Newsletter

Stem Cells for Multiple Sclerosis: Part 2

View this message online Hello manoj kumar valluru, Last week an interesting news story about >20 Texan patients treated with stem cells suffering from multiple sclerosis came out.  We watch these developments with cautious optimism. Click here for the video. A recent paper describing TNF-alpha inhibiting SDF-1 secretion was published.  This may explain some of the osteoclastic effects seen in patients with chronic inflammation.  Another interesting finding was that EPO can inhibit the mouse model of multiple sclerosis through stimulation of Treg and inhibition of Th17.  Maybe this is why some cancer patients do worse if they are on chronic EPO? Two neat patents came out last week.  #7,494,644 covers the transfection of cells (myoblasts and mesenchymal) with connexin-43 to increase their ability to interact with myocardium.  This could be a great way of overcoming arrythmias seen with some myoblast-based approaches.  Irv Weissman continues his patent domination of the field of hematology, getting a patent on the megakaryocytic progenitor (#7,494,807).  He is inventor on the common myeloid progenitor, as well as common lymphoid progenitor patents.  Great job Irv ! Although the majority of studies looking at stem cell mediated immune modulation have been focused on mesenchymal stem cells, a recent paper describes suppression of the mouse model of MS through administration of hematopoietic stem cells, and demonstrated that therapeutic effect was associated with upregulation of indolamine 2,3 deoxygenase in the dendritic cells.    Methods and compositions for correction of cardiac conduction disturbances     Patent Number: 7,494,644 Assignee | Inventor It is known that bone marrow stem cells are mobilized after heart injury such as infarct, with presumable therapeutic effects mediated by the stem cells in terms of stimulating angiogenesis or even integrating into the damaged myocardium and transdifferentiating into de novo [Read More] Ask a question OR leave your comments.     Stem Cell Therapy for Multiple Sclerosis Monday March 2nd, 2009 @ 20:41:36 EST The use of stem cells for treatment of multiple sclerosis has the potential to address both the inflammatory aspects of the disease, as well as induce regeneration.  Below is a clip from a news release describing what appears to be a repeatedly successful treatment of multiple...[Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News   Media Partnerships (NEW)   PATENTS - WHAT'S GETTING ATTENTION?     Methods for altering cell fate to generate T-cells specific for... | 1 Comment(s)     NEWS - WHAT'S GETTING ATTENTION?     Bone Marrow Stem Cells for Renal Failure | 11 Comment(s)     Interferon gamma as a "danger signal" | 2 Comment(s)     RECENTLY ADDED PATENTS     Mammalian megakaryocyte progenitor cell (7,494,807) Assignee | Inventor | Ask a question OR leave your comments     Methods and compositions for correction of cardiac conduction disturbances (7,494,644) Assignee | Inventor | Ask a question OR leave your comments     Methods for altering cell fate to generate T-cells specific for an antigen of interest (7,491,534) Assignee | Inventor | 1 Comment     Uses of fibroblasts or supernatants from fibroblasts for the suppression of immune responses in transplantation (7,491,388) Assignee | Inventor | Ask a question OR leave your comments     Use of glycosylceramides as adjuvants for vaccines against infections and cancer (7,488,491) Assignee | Inventor | Ask a question OR leave your comments     Wound and cutaneous injury healing with a nucleic acid encoding perlecan (7,488,719) Assignee | Inventor | Ask a question OR leave your comments     PSCA: prostate stem cell antigen and uses thereof in pancreatic cancer (7,485,296) Assignee | Inventor | Ask a question OR leave your comments     Enhanced growth of adult stem cells with Dkk-1 (7,485,460) Assignee | Inventor | Ask a question OR leave your comments     Biomaterial derived from vertebrate liver tissue (7,482,025) Assignee | Inventor | Ask a question OR leave your comments     Telomere-encoding synthetic DNA nanocircles, and their use for the elongation of telomere repeats (7,482,332) Assignee | Inventor | Ask a question OR leave your comments     View all 1392 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     Stem Cell Therapy for Multiple Sclerosis 2 hours ago     TNF alpha inhibits SDF-1 increases osteoclast precursors 21 hours ago     EPO Protects from Mouse Multiple Sclerosis 4 days ago     Stem Cell Inhibition of Multiple Sclerosis by IDO Induction February 22nd     Resistance to Fas Induced Apoptosis in Glioma Stem Cells February 13th     Read more news on StemCellPatents.com     LATEST JOBS POSTS     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com. Media Partnerships (NEW) (BETA) ------------------------------------------------------------ To unsubscribe, click here. Delivered: Monday March 2nd, 2009 @ 23:20:27 EST

Nature Cell Biology contents: March 2009 Volume 11 Number 3, pp 227 - 362

NATURE CELL BIOLOGY

March 2009 Volume 11 Number 3, pp 227 - 362

Visit Nature Cell Biology online to browse the journal.

Now available at http://links.ealert.nature.com/ctt?kn=18&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Please note that you need to be a subscriber to enjoy full text access
to Nature Cell Biology online. To purchase a subscription, please visit:
http://links.ealert.nature.com/ctt?kn=79&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Alternatively, to recommend a subscription to your library, please visit
http://links.ealert.nature.com/ctt?kn=50&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

Thermo Scientific DyLight Fluors are the brightest and
most photostable dyes available today! DyLight Fluors cover
the entire visible and infrared spectrum with reactive fluors,
labeling kits, fluorescent conjugates, Western blotting kits,
fluorescent molecular weight markers and protein stains.

http://links.ealert.nature.com/ctt?kn=89&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

=====================================================================

=========================== ADVERTISEMENT ===========================

New insights in signal transduction pathways with Duolink(R) PLA technology

* Detect endogenous proteins, protein interactions and protein modifications in fixed cells
and tissue as countable bright fluorescent spots
* Quantify proteins at physiological expression levels with high specificity and sensitivity

NEW! Anti-human PLA probes available

Learn more here: http://links.ealert.nature.com/ctt?kn=82&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

=====================================================================

=========================== ADVERTISEMENT ===========================

NPG announces a free website for biology classes... Scitable by Nature Education

Scitable is designed to expand students' knowledge of genetics by providing expert, evidence-based content.

To learn more about this exciting, new educational product visit
http://links.ealert.nature.com/ctt?kn=51&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

=====================================================================
----------------------
EDITORIAL
----------------------
Funding boom or bust? p227
The impact of the continuing economic woes on science funding remains
uncertain. Surprisingly, the crisis may actually reinvigorate research.
Investment in science and education is a prerequisite not only for
emergence from the economic downward spiral, but also for addressing
pressing global needs.
doi:10.1038/ncb0309-227
http://links.ealert.nature.com/ctt?kn=13&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

----------------------
REVIEW
----------------------
Many roads to maturity: microRNA biogenesis pathways and their
regulation pp228 - 234
Julia Winter et al.
doi:10.1038/ncb0309-228
Abstract: http://links.ealert.nature.com/ctt?kn=107&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=117&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

----------------------
NEWS AND VIEWS
----------------------
Prions tunnel between cells pp235 - 236
Prions are abnormal isoforms of host proteins that are the infectious
agents in certain mammalian neurodegenerative diseases. How prions
travel from their peripheral entry sites to the brain where they cause
disease is poorly understood. A new study finds that tunnelling nanotubes
are important for the intercellular transfer of prions during neuroinvasion.
Hans-Hermann Gerdes
doi:10.1038/ncb0309-235
http://links.ealert.nature.com/ctt?kn=99&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

When you are Dishevelled, fat is good and acid is bad! pp237 - 239
Frizzled receptors regulate cell fate decisions and planar cell polarity
by means of distinct intracellular effectors. The choice between these
two signalling outputs may involve a pH-dependent interaction between
Dishevelled and negatively charged lipids at the plasma membrane.
Francois Schweisguth
doi:10.1038/ncb0309-237
http://links.ealert.nature.com/ctt?kn=30&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Breast cancer quality control pp239 - 241
Tumorigenesis is regulated by several mechanisms including signalling,
transcription and DNA replication. Now a cytoplasmic protein quality-control
pathway is implicated in the suppression of breast cancer cell growth,
suggesting a new role for quality-control mechanisms in suppressing
cells with malignant potential.
Cam Patterson and Sarah Ronnebaum
doi:10.1038/ncb0309-239
http://links.ealert.nature.com/ctt?kn=64&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Prions remodel gene expression in yeast pp241 - 243
Epigenetic mechanisms participate in the regulation of gene transcription
in eukaryotes. Two studies in yeast have revealed an additional mechanism
for controlling global gene transcription that is based on an inherited
self-perpetuating change in the conformation of two different components
of key transcriptional regulatory complexes.
Mick F. Tuite and Brian S. Cox
doi:10.1038/ncb0309-241
http://links.ealert.nature.com/ctt?kn=92&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

How to grow a bud: an importin acts in asymmetric division
pp243 - 245
The growth of daughter cells in budding yeast is a classic model for
investigating mechanisms involved in asymmetric cell division.
An unexpected collaboration between the DEAD-box protein Dbp5
and the nuclear transport receptor Kap104 controls localized protein
synthesis at the bud tip during mitosis.
David S. Goldfarb
doi:10.1038/ncb0309-243
http://links.ealert.nature.com/ctt?kn=83&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Research highlights p246
doi:10.1038/ncb0309-246
http://links.ealert.nature.com/ctt?kn=118&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

----------------------
ARTICLES
----------------------
Requirement for Nudel and dynein for assembly of the lamin B spindle
matrix pp247 - 256
Lamin B is a component of a membranous matrix thought to be essential
for spindle assembly. The dynein motor and its interacting protein Nudel
are required for the recruitment of lamin B to the spindle matrix.
Li Ma et al.
doi:10.1038/ncb1832
Abstract: http://links.ealert.nature.com/ctt?kn=24&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=20&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Myocardin-related transcription factors and SRF are required for cytoskeletal
dynamics and experimental metastasis pp257 - 268
By preventing G-actin accumulation, Rho-GTPase promotes the transcriptional
activity of myocardin-related transcription factors (MRTFs), known co-factors of
serum response factor (SRF). Rho-dependent MRTF expression is required for
injected metastatic cell lines to colonize the lung.
Souhila Medjkane et al.
doi:10.1038/ncb1833
Abstract: http://links.ealert.nature.com/ctt?kn=4&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=44&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

----------------------
LETTERS
----------------------
NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle
rotation independently of cortical LIN-5/GPR/Galpha pp269 - 277
LIN-5 acts at the cortex with Ga to control spindle positioning but is also
localized at spindle poles. The LIN-5 interacting protein ASPM-1 and
calmodulin are required for its recruitment to spindle poles and the
LIN-5/ASPM-1/calmodulin complex regulates meiotic spindle positioning.
Monique van der Voet et al.
doi:10.1038/ncb1834
Abstract: http://links.ealert.nature.com/ctt?kn=98&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=103&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

An ATM- and ATR-dependent checkpoint inactivates spindle assembly
by targeting CEP63 pp278 - 285
Double-strand breaks in DNA activate the kinases ATM and ATR, which
block entry into mitosis. ATM and ATR also delay mitotic progression by
controlling spindle assembly in Xenopus egg extracts through the
phosphorylation of the centrosomal protein CEP63, leading to its
delocalization from the centrosome.
Eloise Smith et al.
doi:10.1038/ncb1835
Abstract: http://links.ealert.nature.com/ctt?kn=19&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=36&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex
at the plasma membrane during planar epithelial polarization pp286 - 294
A genome-wide RNAi screen reveals the importance of local pH regulation
during planar epithelial polarization. The plasma membrane association of
the planar cell polarity components Dishevelled/Frizzled depends on the
activity of the Na+/H+ membrane exchanger Nhe2.
Matias Simons et al.
doi:10.1038/ncb1836
Abstract: http://links.ealert.nature.com/ctt?kn=70&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=59&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Chfr is linked to tumour metastasis through the downregulation of
HDAC1 pp295 - 302
The ubiquitin ligase Chfr polyubiquitylates the histone deacetylase Hdac1,
resulting in its proteolysis and the concomitant upregulation of metastasis
suppressors, which may provide a molecular explanation for the known
effects of Chfr on tumour progression.
Young Mi Oh et al.
doi:10.1038/ncb1837
Abstract: http://links.ealert.nature.com/ctt?kn=61&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=88&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Intercellular transfer to signalling endosomes regulates an ex vivo bone
marrow niche pp303 - 311
Live-cell imaging shows that haematopoietic progenitor cells contact
osteoblasts through a specialized membrane domain that is consequently
internalized by osteoblasts. This results in downregulation of Smad signalling
and the production of chemokines by osteoblasts that stimulate
haematopoietic progenitor cell homing to bone marrow.
Jennifer M. Gillette, Andre Larochelle, Cynthia E. Dunbar and
Jennifer Lippincott-Schwartz
doi:10.1038/ncb1838
Abstract: http://links.ealert.nature.com/ctt?kn=97&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=9&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic
pathways pp312 - 319
The ubiquitin ligase CHIP suppresses tumour growth and metastasis in
breast cancer, and its expression inversely correlates with malignancy.
The role of CHIP in cancer depends on degradation of the transcriptional
co-activator SRC-3, which regulates expression of Smad and Twist.
Masashi Kajiro et al.
doi:10.1038/ncb1839
Abstract: http://links.ealert.nature.com/ctt?kn=14&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=100&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Oct1 loss of function induces a coordinate metabolic shift that opposes
tumorigenicity pp320 - 327
Cancer cells characteristically undergo a shift from oxidative to glycolytic
metabolism. Loss of the transcription factor Oct1 opposes tumorigenicity
by inducing a coordinate metabolic shift from glucose metabolism to
increased mitochondrial activity and amino acid oxidation.
Arvind Shakya et al.
doi:10.1038/ncb1840
Abstract: http://links.ealert.nature.com/ctt?kn=66&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=65&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Prions hijack tunnelling nanotubes for intercellular spread pp328 - 336
Tunnelling nanotubes provide a means of intercellular communication.
They are now shown to facilitate spreading of prions between neuronal
cells, as well as their propagation from dentritic cells to primary neurons.
Karine Gousset et al.
doi:10.1038/ncb1841
Abstract: http://links.ealert.nature.com/ctt?kn=3&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=49&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

SOAR and the polybasic STIM1 domains gate and regulate Orai channels
pp337 - 343
The molecular determinants of gating and regulation of the calcium channel
Orai1 by the ER Ca2+ sensor STIM1 during store-operated calcium entry
are now defined.
Joseph P. Yuan et al.
doi:10.1038/ncb1842
Abstract: http://links.ealert.nature.com/ctt?kn=29&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=120&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

The yeast global transcriptional co-repressor protein Cyc8 can propagate
as a prion pp344 - 349
The transcriptional activator SWI was recently shown to propagate as a
prion in yeast. Cyc8, a co-repressor that regulates a similar set of genes
as SWI, also propagates as a prion, suggesting a link between chromatin
remodelling and cytoplasmic inheritance of prion traits.
Basant K. Patel, Jackie Gavin-Smyth and Susan W. Liebman
doi:10.1038/ncb1843
Abstract: http://links.ealert.nature.com/ctt?kn=72&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=94&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

Nuclear transport factor directs localization of protein synthesis
during mitosis pp350 - 356
The intracellular localization of the karyopherin KAP104 determines where
dissociation of the mRNA binding proteins Nab2 and Nab4 from translation
competent mRNAs takes place, thus controlling local protein synthesis.
Geert van den Bogaart et al.
doi:10.1038/ncb1844
Abstract: http://links.ealert.nature.com/ctt?kn=47&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=27&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

The heterochromatin protein Swi6/HP1 activates replication origins at the
pericentromeric region and silent mating-type locus pp357 - 362
The replication of heterochromatic chromosome regions is temporally
regulated. The yeast heterochromatin protein Swi6 (mammalian HP1)
activates replication origins by recruiting the kinase Dfp1, which facilitates
loading of replication factor Sld3 on early replicating heterochromatin.
Makoto T. Hayashi et al.
doi:10.1038/ncb1845
Abstract: http://links.ealert.nature.com/ctt?kn=119&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=63&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================

Protein modifications: beyond the usual suspects

EMBO reports web focus

Get a sense of the molecular diversity that exists within cells! This series of comprehensive and engaging reviews highlights the complexity of post-translational protein modifications. Leading experts analyze atypical ubiquitin-chain formation, ATGylation, polyglutamylation, neddylation, and Urmylation, and update our knowledge on poly(ADP-ribosyl)ation and O-GlcNAcylation.
A complex but important topic to understand!

http://links.ealert.nature.com/ctt?kn=22&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0

=====================================================================

You have been sent this Table of Contents Alert because you have opted in to
receive it. You can change or discontinue your e-mail alerts at any time,
by modifying your preferences on your nature.com account at:
http://links.ealert.nature.com/ctt?kn=23&m=31801783&r=MTc2NDEyMTk0MQS2&b=2&j=NDYyMjI1NjYS1&mt=1&rt=0
(You will need to log in to be recognised as a nature.com registrant).

For further technical assistance, please contact our registration department:
registration@nature.com

For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com

For other enquiries, please contact our customer feedback department:
feedback@nature.com

Nature Publishing Group | 75 Varick Street, 9th Floor | New York |
NY 10013-1917 | USA

Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne -
San Diego - San Francisco - Washington - New York - Boston

(c) Copyright 2009 Nature Publishing Group

=====================================================================

Cell Research - Table of Contents alert Volume 19 Issue 3

CELL RESEARCH

March 2009 Volume 19 Number 3, pp 275 - 394

--------------------------------------------------------------------------

Genetics and Genomics of Infectious Diseases 2009

March 21-24, 2009
Ritz Carlton Millenia, Singapore

This conference will engage basic and clinical scientists, including
human geneticists, genome scientists, computational biologists, and
experts in pathogenic microbial agents to chart the effects of genomics
on questions in global infectious disease management.

For more information and to register visit:
http://links.ealert.nature.com/ctt?kn=60&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

--------------------------------------------------------------------------

Cell Research
Get your free online issue today!

Cell Research delivers the latest content covering:
- Cell growth and differentiation
- Cytoskeleton
- Signaling
- Apoptosis
- Stem cells
- Immunology
- Chromatin and transcription
- Cell cycle
- Plant cell biology

Published 12 times a year, Cell Research is an excellent source for the latest
findings in the field. Visit
http://links.ealert.nature.com/ctt?kn=8&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
to view a free issue today!

----------------------
RESEARCH HIGHLIGHTS
----------------------
Insulin resistance: [beta]-arrestin development
Joseph T Rodgers and Pere Puigserver
http://links.ealert.nature.com/ctt?kn=56&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

A "memorable" NK cell discovery
Noah S Butler and John T Harty
http://links.ealert.nature.com/ctt?kn=77&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

Tissue-specific stem cells: friend or foe?
Joerg Huelsken
http://links.ealert.nature.com/ctt?kn=70&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

----------------------
REVIEW
----------------------
Epigenetics: heterochromatin meets RNAi
Ingela Djupedal and Karl Ekwall
Abstract: http://links.ealert.nature.com/ctt?kn=36&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=69&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

----------------------
ORIGINAL ARTICLES
----------------------
Generation of iPS cells using defined factors linked via the self-cleaving 2A
sequences in a single open reading frame
Lijian Shao, Wei Feng, Yan Sun, Hao Bai, Jun Liu, Caroline Currie, Jaejung Kim,
Rafael Gama, Zack Wang, Zhijian Qian, Lucy Liaw and Wen-Shu Wu
Abstract: http://links.ealert.nature.com/ctt?kn=13&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=25&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

The Arabidopsis homologs of CCR4-associated factor 1 show mRNA deadenylation
activity and play a role in plant defence responses
Wenxing Liang, Changbao Li, Fang Liu, Hongling Jiang, Shuyu Li, Jiaqiang Sun,
Xiaoyan Wu and Chuanyou Li
Abstract: http://links.ealert.nature.com/ctt?kn=84&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=33&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

Endocytosis of adiponectin receptor 1 through a clathrin- and Rab5-dependent pathway
Qiurong Ding, Zhenzhen Wang and Yan Chen
Abstract: http://links.ealert.nature.com/ctt?kn=18&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=17&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of
epidermal keratinocytes to terminal differentiation
Sam M Janes, Tyler A Ofstad, Douglas H Campbell, Ayad Eddaoudi, Gary Warnes,
Derek Davies and Fiona M Watt
Abstract: http://links.ealert.nature.com/ctt?kn=65&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=32&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

c-Fos enhances the survival of thymocytes during positive selection by upregulating Bcl-2
Xiaoming Wang, Yafeng Zhang, Gang Xiao, Xiang Gao and Xiaolong Liu
Abstract: http://links.ealert.nature.com/ctt?kn=35&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=80&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

RNF13: a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer
Qiang Zhang, Yunxiao Meng, Lei Zhang, Jie Chen and Dahai Zhu
Abstract: http://links.ealert.nature.com/ctt?kn=42&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=26&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC
formation and caspase-8-dependent apoptotic death in T leukemic cells
Tanvi S Jani, Leila Gobejishvili, Prachi T Hote, Aditya S Barve, Swati Joshi-Barve,
Giorgi Kharebava, Jill Suttles, Theresa Chen, Craig J McClain and Shirish Barve
Abstract: http://links.ealert.nature.com/ctt?kn=78&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=63&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

Serial imaging of human embryonic stem-cell engraftment and teratoma formation in
live mouse models
Martin G Pomper, Holly Hammond, Xiaobing Yu, Zhaohui Ye, Catherine A Foss, Doris D Lin,
James J Fox and Linzhao Cheng
Abstract: http://links.ealert.nature.com/ctt?kn=2&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=48&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

Studies on rice seed quality through analysis of a large-scale T-DNA insertion population
Fang-Fang Fu, Rui Ye, Shu-Ping Xu and Hong-Wei Xue
Abstract: http://links.ealert.nature.com/ctt?kn=52&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=49&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

----------------------
LETTER TO THE EDITOR
----------------------
Structure-function analysis of Eiger, the Drosophila TNF homolog
Rajesh Narasimamurthy, Peter Geuking, Karine Ingold, Laure Willen, Pascal Schneider and Konrad Basler
http://links.ealert.nature.com/ctt?kn=9&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

--------------------------------------------------------------------------

Lymphocytes Return Home

Immunology & Cell Biology is proud to bring you
Lymphocytes Return Home - a focus that brings together a collection
of articles representing our current understanding of how numerous
cell types can return to the thymus. Accompanying this focus is a
special feature dealing with the nature and possible functional
consequences of cellular traffic, both lymphoid and myeloid, back to
the primary lymphoid organs.

Take advantage of this limited time offer today!
Lymphocytes Return Home
http://links.ealert.nature.com/ctt?kn=79&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0

=====================================================================

You have been sent this Table of Contents Alert because you have opted in to receive it.
You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at:
http://links.ealert.nature.com/ctt?kn=34&m=31801316&r=MTc2MDE3NzA4MwS2&b=2&j=NDYyMTg5NTUS1&mt=1&rt=0
(You will need to log in to be recognised as a nature.com registrant).

For further technical assistance, please contact our registration department:
registration@nature.com

For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com

For other enquiries, please contact customer feedback department:
feedback@nature.com

Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA

Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne - San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS.

© Copyright 2009 Nature Publishing Group

=====================================================================