March 2009 Volume 5 Number 3
Visit Nature Clinical Practice Rheumatology online to browse the journal.
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Reviews Rheumatology, with a new look and additional content.
For more information visit:
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EDITORIAL
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Available therapeutic options following failure of a first anti-TNF
agent
Alan J Silman
http://links.ealert.nature.com/ctt?kn=79&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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RESEARCH HIGHLIGHTS
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Successful targeting of mesangial cells using immunoliposomes
http://links.ealert.nature.com/ctt?kn=57&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Skin involvement does not predict severe complications of systemic
sclerosis
http://links.ealert.nature.com/ctt?kn=1&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Hypoxia enhances production of functional cartilage from stem cells
http://links.ealert.nature.com/ctt?kn=81&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
New strategies have more impact than drug choice on improvements in RA
management
http://links.ealert.nature.com/ctt?kn=11&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Bortezomib improves arthritis in a mouse model
http://links.ealert.nature.com/ctt?kn=64&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Respiratory ciliary function is impaired in Wegener's granulomatosis
http://links.ealert.nature.com/ctt?kn=77&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Cardiotrophin-1 signaling essential for normal mouse bone resorption
and formation
http://links.ealert.nature.com/ctt?kn=69&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
In brief
http://links.ealert.nature.com/ctt?kn=42&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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GUIDELINES SUMMARY
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Pharmacologic therapy to reduce fracture risk: comment on the clinical
practice guidelines of the ACP
E Michael Lewiecki
http://links.ealert.nature.com/ctt?kn=45&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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PRACTICE POINTS
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Is arthroscopic surgery a beneficial treatment for knee osteoarthritis?
Richard W Nutton
http://links.ealert.nature.com/ctt?kn=17&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Are static resting wrist splints beneficial in early RA?
Theodora PM Vliet Vlieland
http://links.ealert.nature.com/ctt?kn=12&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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CLINICAL ADVANCES
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How do the efficacy and safety of abatacept and infliximab compare in
the treatment of active RA?
Peter C Taylor
http://links.ealert.nature.com/ctt?kn=39&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Is tocilizumab in combination with traditional DMARDs safe and
effective for patients with active RA?
Eugen Feist and Gerd-R Burmester
http://links.ealert.nature.com/ctt?kn=38&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Is spleen tyrosine kinase inhibition an effective therapy for patients
with RA?
Axel J Hueber and Iain B McInnes
http://links.ealert.nature.com/ctt?kn=80&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
A new 5-lipoxygenase inhibitor seems to be safe and effective for the
treatment of osteoarthritis
Frances MK Williams and Tim D Spector
http://links.ealert.nature.com/ctt?kn=83&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Cerotlizumab pegol-what role does this new TNF inhibitor have in
the treatment of RA?
Daniel E Furst
http://links.ealert.nature.com/ctt?kn=21&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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VIEWPOINT
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Time for new outcome measures in hand osteoarthritis?
Emmanuel Maheu and Francis Berenbaum
http://links.ealert.nature.com/ctt?kn=26&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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REVIEWS
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Cardiac manifestations of neonatal lupus erythematosus: guidelines to
management, integrating clues from the bench and bedside
Jill P Buyon, Robert M Clancy and Deborah M Friedman
http://links.ealert.nature.com/ctt?kn=73&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
Imaging the painful osteoarthritic knee joint: what have we learned?
Claire YJ Wenham and Philip G Conaghan
http://links.ealert.nature.com/ctt?kn=24&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
New approaches for managing antiphospholipid syndrome
Doruk Erkan and Michael D Lockshin
http://links.ealert.nature.com/ctt?kn=3&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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CASE STUDY
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Clinical and radiographic response to a local infliximab injection in
a patient with chronic sacroiliitis
Finbar D O'Shea, Nigil Haroon, David C Salonen and Robert D Inman
http://links.ealert.nature.com/ctt?kn=28&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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ERRATUM
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Potential new drug targets for osteoporosis
Chad Deal
http://links.ealert.nature.com/ctt?kn=51&m=31803477&r=MTc2NDQ4MTc5OAS2&b=2&j=NDYyMzg0NDkS1&mt=1&rt=0
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Lymphocytes Return Home
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