Stem Cell: January 2008

Thursday, January 31, 2008

Keyword News: [stem cell]

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Thursday, January 31, 2008 10:31 PM PST

UTMB gets grant for stem cell research
Galveston County Daily News Thu, 31 Jan 2008 9:57 PM PST
GALVESTON — A $500,000 grant from the Cullen Foundation will support neurological stem cell research at the University of Texas Medical Branch by funding the purchase of an advanced microscope and supporting a postdoctoral fellow who assists in the studies to optimize stem cell therapy.

Stem cell treatment for babies with brittle bones in the womb
News-Medical-Net Thu, 31 Jan 2008 3:24 PM PST
The extraordinary results of an in utero stem cell treatment could lead to a new treatment for babies with brittle bones, as well as a range of other disabling conditions, according to a maternal-fetal medicine researcher, now based at The University of Queensland (UQ).

Stem cell therapy studies for stroke, cerebral palsy prepare for clinical trials
News-Medical-Net Thu, 31 Jan 2008 2:53 PM PST
Finding answers about optimal dosage and timing for stem cell therapy in adults with strokes and newborns with ischemic injuries is a goal of two new federally funded studies.

Stem cell research bill clears Senate
Las Cruces Sun-News Wed, 30 Jan 2008 11:10 PM PST
For more stories from the 2008 legislative session, click here. SANTA FE — For the second year in a row, a bill authorizing stem cell research on embryos in New Mexico has been narrowly approved by the state Senate.

Acacia dodges stem cell surgery
Stawell Times-News Thu, 31 Jan 2008 9:46 PM PST
Acacia Ridge has escaped an operation to repair an injured tendon. Owner Robyn Van Maanen was delighted to report that scans early last week revealed that the injury, sustained in early January, had greatly improved.

CORD:USE Cord Blood Bank Announces the Addition of Dr. John Wagner, a Pioneer in the Use of Umbilical Cord Blood Stem ...
Press Trust of India Thu, 31 Jan 2008 1:26 AM PST
John Wagner, M.D., recognized as a leader in the field of cord blood stem cell transplantation, has joined the team at CORD:USE Cord Blood Bank. Dr. Wagner's extensive experience and knowledge in transplant medicine and stem cell biology will provide a significant contribution to CORD:USE.

Pope condemns human cloning and stem cell research
Daily Mail Thu, 31 Jan 2008 8:39 AM PST
Pope Benedict XVI has issued a forceful condemnation of human cloning and destructive experimentation on embryos

Pope defends bioethics teaching
AP via Yahoo! News Thu, 31 Jan 2008 12:13 PM PST
Pope Benedict XVI on Thursday defended the Vatican's right to speak out on bioethics, including its opposition to artificial procreation methods and embryonic stem cell research.

Pope says some science shatters human dignity
Reuters via Yahoo! News Thu, 31 Jan 2008 6:57 AM PST
Pope Benedict said on Thursday that embryonic stem cell research, artificial insemination and the prospect of human cloning had "shattered" human dignity.

Some science shatters human dignity
TVNZ Thu, 31 Jan 2008 10:26 PM PST
Pope Benedict said that embryonic stem cell research, artificial insemination and the prospect of human cloning had shattered human dignity.

See more news stories that match my keyword

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Australian Life Scientist Weekly | Batman's place in evolution / More twists to Avandia saga

Friday 1st February 2008

Australian Life Scientist Weekly

Batman's place in evolution
Professor Emeritus Jack Pettigrew has argued for more than two decades that fruit bats are actually flying primates, distant relatives of monkeys, lemurs and us. More...

More twists to Avandia saga
Nature reports that a peer reviewer leaked an unfavourable report on diabetes drug Avandia to manufacturer. More...

Science and the supercomputer
High performance computing is stimulating collaborative research across state - and country - borders. More...

More than just auditory cheesecake
Alan Harvey will discuss neurotrauma research, Cliff Richard and the role of music in the evolution of the modern mind at the ANS meeting this week. More...

Beta news for pancreatic stem cells
Elusive pancreatic stem cells found in adult mice, Belgian researchers say. More...

Marker for thymic stem cells identified
Scottish and Australian researchers have identified a protein marker for thymic and possibly pancreatic stem cells. More...

Findlay gets another gong
Jock Findlay becomes an AO in this year's honours list. More...

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[StemCells] Vaccine Induced Demyelination

Vaccine Induced Demyelination

http://www.healing- arts.org/ children/ vaccines/ vaccines- demyelination. htm

Myelination is an essential part of human brain development. Nerves can only conduct pulses of energy efficiently if covered by myelin. Like insulation on an electric wire, the fatty coating of myelin keeps the pulses confined and maintains the integrity of the electrical signal so that it has a high signal-to-noise ratio. When the insulation on a wire is damaged or destroyed, the flow of electrical current may be interrupted and a short-circuit occurs.

Oligodendrocyte cells give white matter its color by manufacturing myelin. If myelin falls into disrepair, nerve axons cease to function, even though they themselves aren't damaged. Protecting oligodendrocytes after brain or spinal cord injury might keep nerve cells intact.

At birth, relatively few pathways have myelin insulation. Myelination in the human brain continues from before birth until at least 20 years of age. Up until the age of 10 or so, vast areas of the cortex are not yet myelinated. Up to the age of 20, large areas of the frontal lobes are not yet myelinated. 1

Myelination begins in the developmentally oldest parts of the brain, like the brain stem, moving to the areas of the nervous system that have developed more recently, like the prefrontal lobe and cortex. Myelin spreads throughout the nervous system in stages, which vary slightly in each individual. Impairment of myelination can alter neural communication without necessarily causing severe CNS (central nervous system) damage.

The prefrontal portions of the cerebrum have a profound influence on human behavior. 2 If an individual is injected with vaccines,most of which have adjuvants like mercury and aluminum compounds, as well as foreign proteins (some from other species in which the vaccines were grown) and biological organisms, unprotected nerves may be impacted. The argument for a role of vaccines in the development of autistic disorders hinges on these biological effects upon nerves, damaging them in a way that influences behavior and learning patterns.

The argument for adjuvants evoking an auto-immune response does not hinge on any inherent neuro-toxicity of these compounds, but on the initiation of an allergic response.

The model by which adjuvants initiate an immune response is that of Experimental Allergic Encephalomyelitis (EAE). To date, EAE is recognized as the best available animal model of several degenerative human diseases, like multiple sclerosis and post-vaccinal encephalopathies. EAE 3 is generally thought to be an autoimmune response to myelin basic protein ( MBP ). Oddly, MBP can also suppress EAE, and many observations suggest that an independent immune response to so-called "adjuvant" material is also necessary to EAE induction. Of course, this is why adjuvants are used in vaccines, to dramatically increase the likelihood of an immune response to the administered biological material.

Thus, EAE may be a result of a pair of interactive immune responses, one against MBP , and one against the adjuvant. If so, the adjuvant should, like MBP , suppress EAE. Root-Bernstein, et al. (1986) presented data from experiments on strain 13 guinea pigs demonstrating EAE suppression by muramyl dipeptide, an active component of complete Freund's adjuvant. In the past, adjuvants have only been classified as immunopotentiators, not immunosuppressants. Apparently, adjuvants are both. This study strengthens the argument that adjuvants may be crucial to initiating an auto-immune response leading to post-vaccine neurological symptoms.

[ Return to "Quick-Index" of Vaccines ]

References

1. Edwards KM, Meade BD, Decker MD, et al. Comparison of 13 acellular pertussis vaccines: overview and serologic responses. Pediatrics 1995;96:548- 57.

2. Orenstein WA , Brugliera PD. Preface: Immunization in medical education. Am J Prev Med 1994; 10(suppl):v- viii.

3. Root-Bernstein RS; Yurochko F; Westall FC. Clinical suppression of experimental allergic encephalomyelitis by muramyl dipeptide "adjuvant". Brain Res Bull, 17: 4, 1986 Oct, 473-6.

Also:

Auto-Immunity, Vaccines and Autism

http://www.healing- arts.org/ children/ vaccines/ vaccines- auto-immunity. htm#auto

Auto-Immunity, Vaccines and Autism

http://www.healing- arts.org/ children/ vaccines/ vaccines- auto-immunity. htm#auto

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Nature Clinical Practice Rheumatology - Table of Contents alert Volume 4 Issue 2

NATURE CLINICAL PRACTICE RHEUMATOLOGY

February 2008 Volume 4 Number 2

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pursuing
Edward C Keystone
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgH0EY

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Cytokines and joint erosion in arthritis
Wim B van den Berg
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Hormone replacement therapy in systemic lupus erythematosus
Chi Chiu Mok
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Dual-energy X-ray absorptiometry is a highly sensitive measure of bone
loss in early RA
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgK0Eb

Adrenomedullin is associated with hypertension in patients with systemic
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DDR2 blockade might be a good treatment option for patients with OA
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgM0Ed

Presence of bone edema on MRI might determine disease severity in
patients with early RA
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgN0Ee

Fibrin is a potential therapeutic target for the treatment of inflammatory
disease
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgO0Ef

Lubricin reduces friction and prevents wear and tear at the cartilage
surface
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgP0Eg

Is the synovio-entheseal complex involved in the pathogenesis of synovitis?
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgQ0Eh

Salivary protein and RNA biomarkers for Sjogren's syndrome
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ANCAs do not predict disease activity in Wegener's granulomatosis
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgS0Ej

Human TH17 induction-treading the line between inflammation and
regulation
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgT0Ek

People now live longer-unless they have RA
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgU0El

Intensive exercise training following hospital discharge benefits
patients with OA or RA
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgV0Em

Could manipulation of the lipoxin system lead to new therapy for RA?
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgW0En

Concurrent bisphosphonate therapy reduces osteoporotic effects of
glucocorticoids
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgX0Eo

----------------------
PRACTICE POINTS
----------------------
Is surgery more effective than nonsurgical treatment for the management
of patients with degenerative spondylolisthesis?
JN Alastair Gibson and Chye-Yew Ng
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgY0Ep

Does calcium supplementation reduce the risk of osteoporotic fracture
and bone loss?
Luigi Gennari and Giuseppe Martini
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0BmgZ0Eq

Do exercise and advice help to improve the symptoms of subacute low
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John P Ney
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----------------------
REVIEWS
----------------------
Chronic nonmalignant pain: a challenge for patients and clinicians
Luca Scascighini and Haiko Sprott
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Tendinopathy-from basic science to treatment
Graham Riley
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Synoviolin, protein folding and the maintenance of joint homeostasis
Naoko Yagishita, Satoshi Yamasaki, Kusuki Nishioka and Toshihiro Nakajima
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0Bmgd0E1

Mechanisms of Disease: macrophage migration inhibitory factor in SLE,
RA and atherosclerosis
Sally Ayoub, Michael J Hickey and Eric F Morand
http://ealerts.nature.com/cgi-bin24/DM/y/eiwA0Xztnp0HjN0Bmge0E2

----------------------
CASE STUDY
----------------------
Conversion of discoid lupus to antiphospholipid syndrome and SLE
Michelle MA Fernando and David A Isenberg
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EDITORIAL
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Health insurance reform-beware of the general solution for the specific
problem
Vincent T DeVita Jr
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VIEWPOINTS
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Screening for breast cancer: is it globally applicable?
Indraneel Mittra
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmek0Et

Are women with breast cancer receiving sufficient education and
information about their treatment?
Yvonne Wengstrom
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----------------------
RESEARCH HIGHLIGHTS
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Identifying factors associated with increased mortality risk in stage I
NSCLC
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmem0Ev

Radiotherapy increases risk of secondary cancer in patients with cervical
cancer
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmen0Ew

Plasma HER2 and EGFR levels are prognostic factors in patients with
prostate cancer
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmeo0Ex

Radiofrequency ablation increases survival in colorectal cancer with
liver metastases
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmep0Ey

Prostatectomy confers the best chance of long-term prostate-cancer-specific
survival
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmeq0Ez

Preoperative radiotherapy reduces risk of local recurrence after total
mesorectal excision
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Abnormal p53 expression is a prognostic factor in locally advanced
prostate cancer
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmes0E2

Combined HPV and Pap testing is a potentially beneficial screening approach
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmet0E3

Complete estrogen blockade in advanced postmenopausal receptor-positive
breast cancer
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmeu0E4

Patients who survive 10 years after resection of colorectal liver
metastases are cured
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmev0E5

Level of HER2 amplification correlates with response to trastuzumab-based
therapy
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmew0E6

Study identifies 10-gene signature prognostic for survival in stage I
lung adenocarcinoma
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmex0E7

Upgrading Gleason score 7 and tertiary grade 5 prostate cancer is warranted
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmey0E8

Combined therapy improves survival in advanced-stage endometrial cancer
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bmez0EA

----------------------
PRACTICE POINTS
----------------------
Is double autologous stem-cell transplantation appropriate for new multiple
myeloma patients?
Frits van Rhee
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bme10Ev

Is oxaliplatin combined with weekly bolus 5-fluorouracil and leucovorin
an option for stage II and III colon cancer?
Chris Twelves
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bme20Ew

What effect does androgen suppression therapy have on frequency and
timing of fatal myocardial infarctions?
Jeffrey M Holzbeierlein
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bme30Ex

Switching to anastrozole after tamoxifen improves survival in
postmenopausal women with breast cancer
Francesco Boccardo
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----------------------
REVIEWS
----------------------
Gonadal failure after treatment of hematologic malignancies: from
recognition to management for health-care providers
Kazutaka Nakayama, Andrea Milbourne, Leslie R Schover, Richard E Champlin
and Naoto T Ueno
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bme50Ez

The etiology and management of intractable breathlessness in patients
with advanced cancer: a systematic review of pharmacological therapy
Sara Booth, Shakeeb H Moosavi and Irene J Higginson
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bme60E1

Drug Insight: gastrointestinal stromal tumors (GIST)-the solid tumor
model for cancer-specific treatment
Stefan Sleijfer, Erik Wiemer and Jaap Verweij
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bme70E2

----------------------
CASE STUDY
----------------------
Improved outcome with multimodality therapy in primary cardiac angiosarcoma
Courtney Pigott, Michael Welker, Pam Khosla and Robert SD Higgins
http://ealerts.nature.com/cgi-bin24/DM/y/eiv70Xztnp0HjM0Bme80E3

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Editorial
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A QUANTUM OF SOLACE
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News
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CASH FOR RUSSIAN NUCLEAR SCIENTISTS CRITICIZED
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SNAPSHOT: SEARCH FOR HIGGS PRIMED TO START
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News in brief
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FRANCE AND INDIA TO EXPAND SCIENTIFIC COLLABORATIONS
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Books and arts
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VAN ALLEN REMEMBERED AS BELTS TURN 50
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News and views
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NANOMATERIALS: GOLDEN HANDSHAKE
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COSMOLOGY: AN ANCIENT VIEW OF ACCELERATION
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DEVICE PHYSICS: NANOWIRES' DISPLAY OF POTENTIAL
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Letters
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A TEST OF THE NATURE OF COSMIC ACCELERATION USING GALAXY REDSHIFT
DISTORTIONS
L. Guzzo et al.
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmYJ0Ed

ORIGIN OF MORPHOTROPIC PHASE BOUNDARIES IN FERROELECTRICS
Muhtar Ahart et al.
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmYL0Ef

DNA-GUIDED CRYSTALLIZATION OF COLLOIDAL NANOPARTICLES
Dmytro Nykypanchuk, Mathew M. Maye, Daniel van der Lelie & Oleg Gang
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmYN0Eh

DNA-PROGRAMMABLE NANOPARTICLE CRYSTALLIZATION
Sung Yong Park et al.
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmYP0Ej

TOWARDS THE ZERO-SURFACE-TENSION LIMIT IN GRANULAR FINGERING INSTABILITY
Xiang Cheng, Lei Xu, Aaron Patterson, Heinrich M. Jaeger
& Sidney R. Nagel
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmhD0Em

CRUISING THROUGH MOLECULAR BOUND-STATE MANIFOLDS WITH RADIOFREQUENCY
F. Lang et al.
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmeM0Es

ULTRAFAST X-RAY STUDY OF DENSE-LIQUID-JET FLOW DYNAMICS USING
STRUCTURE-TRACKING VELOCIMETRY
Yujie Wang et al.
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmeN0Et

LOCALIZATION IN SILICON NANOPHOTONIC SLOW-LIGHT WAVEGUIDES
Shayan Mookherjea, Jung S. Park, Shun-Hui Yang & Prabhakar R. Bandaru
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmO40E6

-------------------------------
Articles
-------------------------------

OPTICAL PHASE CONJUGATION FOR TURBIDITY SUPPRESSION IN BIOLOGICAL SAMPLES
Zahid Yaqoob, Demetri Psaltis, Michael S. Feld & Changhuei Yang
http://ealerts.nature.com/cgi-bin24/DM/y/eiv40Xztnp0Hjm0BmPD0EO

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Cord Blood America (OTC BB: CBAI) CEO...

Release #:812-48146-em-434148:

Cord Blood America (OTC BB: CBAI) CEO Says Company Is Fastest Growing in Entire Sector

Cord Blood America CEO Says 2008 Will See Significant Reduction in Company's Debt

SANTA MONICA, Calif., Jan. 31 /PRNewswire-FirstCall/ -- Cord Blood America, Inc. (OTC Bulletin Board: CBAI - News), the umbilical cord blood stem cell preservation company (http://www.cordblood-america.com) focused on bringing the life saving potential of stem cells to families nationwide and internationally, announced today that Matthew Schissler, CEO, was interviewed by Francis Gaskins of StoxRox.com on the Company's achievements and future outlook. Mr. Schissler said in the interview that a key goal in 2008 is to continue to significantly reduce debt, allowing the Company to operate off its own cash flow.

    The complete interview is available at http://www.stoxrox.com/cbai-jan-b.mp3.

Mr. Schissler said the Company's customer base grew from 3,000 to 18,000 in 2007, a 500 percent increase. He said that organic growth achieved an 85 percent increase since December 31, 2006. "With a yearly storage fee of $100, this provides Cord Blood America with $1.8 million in recurring top line revenue that investors can bank on," Mr. Schissler said.

"We told investors that we would grow as fast as possible in 2006 and 2007, and I believe we executed on that promise. In 2008, investors should look for a significant reduction in debt," Cord Blood America's CEO said.

"We have grown faster than any other cord blood company in the industry, which took a lot of funding. Our valuation is much lower than our competitors and we look for improvement as we decrease this debt level," Mr. Schissler said in the Internet interview.

About Cord Blood America

Cord Blood America (OTC Bulletin Board: CBAI - News) is the parent company of CorCell, which facilitates umbilical cord blood stem cell preservation for expectant parents and their children. Its mission is to be the most respected stem cell preservation company in the industry. Collected through a safe and non-invasive process, cord blood stem cells offer a powerful and potentially life-saving resource for treating a growing number of ailments, including cancer, leukemia, blood, and immune disorders. To find out more about Cord Blood America, Inc. (OTC Bulletin Board: CBAI - News), visit our website at http://www.corcell.com. For investor information, visit http://www.cordblood-america.com.

Forward-Looking Statements

Some statements made in this press release are forward-looking statements, which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. We use words such as "anticipate," "believe," "expect," "future," "intend," "plan," and similar expressions to identify forward-looking statements. These statements including those related to the growth of the industry, new stem cell treatments, and the Company's performance, are only predictions and are subject to certain risks, uncertainties and assumptions. Additional risks are identified and described in the Company's public filings with the Securities and Exchange Commission. Statements made herein are as of the date of this press release and should not be relied upon as of any subsequent date. The Company's past performance is not necessarily indicative of its future performance. The Company does not undertake, and the Company specifically disclaims any obligation to update any forward-looking statements to reflect occurrences, developments, events, or circumstances after the date of such statement.

     CONTACT: Paul Knopick E & E Communications 949/707-5365 pknopick@eandecommunications.com

Source: Cord Blood America, Inc.

My EANDE

More Information

Kidney International Table of Contents alert Volume 73 Issue 4

NEW from KI: the Kidney Podcast! Visit www.nature.com/ki/podcast today!
To listen as top researchers discuss their work with KI Editors, visit www.nature.com/ki/podcast/index.html#Episodes.

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If you are unable to access the articles in this Table of Contents e-alert,
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KIDNEY INTERNATIONAL

February 2008 Volume 73 Number 4, pp 371 - 518

----------------------
IN THIS ISSUE
----------------------
In this Issue
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPi0Ec

----------------------
EDITORIAL
----------------------
The third World Kidney Day: Looking back and thinking forward
Sudhir V Shah and John Feehally
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPj0Ed

----------------------
COMMENTARIES
----------------------
Unraveling the role of connective tissue growth factor in diabetic nephropathy
K M Schmidt-Ott
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPk0Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPl0Ef

Metabolic acidosis and vascular calcification: Using blueprints from bone to map a new venue for vascular research
Z Al-Aly
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPm0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPn0Eh

Peeking into the black box: New biomarkers for acute kidney injury
J M Thurman and C R Parikh
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPo0Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPp0Ej

----------------------
JOURNAL CLUB
----------------------
Journal Club
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPq0Ek

----------------------
TRANSLATIONAL NEPHROLOGY
----------------------
Exploring the biology of vascular calcification in chronic kidney disease: What's circulating?
M Schoppet, R C Shroff, L C Hofbauer and C M Shanahan
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPr0El
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPs0Em

----------------------
MEETING REPORT
----------------------
A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease
D Fouque, K Kalantar-Zadeh, J Kopple, N Cano, P Chauveau, L Cuppari, H Franch, G Guarnieri, T A Ikizler, G Kaysen, B Lindholm, Z Massy, W Mitch, E Pineda, P Stenvinkel, A Trevinho-Becerra and C Wanner
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPt0En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPu0Eo

----------------------
MINIREVIEW
----------------------
Podocyte injury in focal segmental glomerulosclerosis: Lessons from animal models (a play in five acts)
V D D'Agati
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPv0Ep
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPw0Eq

----------------------
ORIGINAL ARTICLES
----------------------
Metabolic acidosis inhibits soft tissue calcification in uremic rats
F J Mendoza, I Lopez, A Montes de Oca, J Perez, M Rodriguez and E Aguilera-Tejero
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPx0Er
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPy0Es

Expression and role of connexins in the rat renal vasculature
T Takenaka, T Inoue, Y Kanno, H Okada, K R Meaney, C E Hill and H Suzuki
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmPz0Et
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP10Eg

Effect of bolus and divided feeding on urine ions and supersaturation in genetic hypercalciuric stone-forming rats
D A Bushinsky, A C Michalenka, K L Strutz, S Donahue and J R Asplin
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP20Eh
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP30Ei

The phosphoinositide-3 kinase [gamma]-Akt pathway mediates renal tubular injury in cisplatin nephrotoxicity
H Kuwana, Y Terada, T Kobayashi, T Okado, J M Penninger, J Irie-Sasaki, T Sasaki and S Sasaki
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP40Ej
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP50Ek

Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice
H Yokoi, M Mukoyama, K Mori, M Kasahara, T Suganami, K Sawai, T Yoshioka, Y Saito, Y Ogawa, T Kuwabara, A Sugawara and K Nakao
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP60El
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP70Em

Interactions of the growth-related, type IIc renal sodium//phosphate cotransporter with PDZ proteins
R Villa-Bellosta, M Barac-Nieto, S Y Breusegem, N P Barry, M Levi and V Sorribas
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmP80En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQA0Ex

Liver fatty acid-binding protein as a biomarker of acute kidney injury after cardiac surgery
D Portilla, C Dent, T Sugaya, K K Nagothu, I Kundi, P Moore, E Noiri and P Devarajan
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQB0Ey
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQC0Ez

High prevalence of chronic kidney disease in Thailand
V Perkovic, A Cass, A A Patel, P Suriyawongpaisal, F Barzi, S Chadban, S MacMahon and B Neal
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQD0E1
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQE0E2

Automated and continuous ambulatory peritoneal dialysis have similar outcomes
S V Badve, C M Hawley, S P Mcdonald, D W Mudge, J B Rosman, F G Brown and D W Johnson
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQF0E3
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQG0E4

24-h uric acid excretion and the risk of kidney stones
G C Curhan and E N Taylor
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQH0E5
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQI0E6

----------------------
TECHNICAL NOTE
----------------------
A wearable hemofilter for continuous ambulatory ultrafiltration
V Gura, C Ronco, F Nalesso, A Brendolan, M Beizai, C Ezon, A Davenport and E Rambod
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQJ0E7
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQK0E8

----------------------
THE RENAL CONSULT
----------------------
Acute onset of hematuria and proteinuria associated with multiorgan involvement of the heart, liver, pancreas, kidneys, and skin in a patient with Henoch-Schonlein purpura
M Zaidi, N Singh, M Kamran, N Ansari, S H Nasr and A Acharya
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQL0EA

----------------------
LETTERS TO THE EDITOR
----------------------
Chronically decreased GFR and cardiovascular risk in living kidney donors
N Seyahi
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQM0EB

Response to /`Chronically decreased GFR and cardiovascular risk in living kidney donors/'
C C Geddes and R Wan
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQN0EC

Response to /`Chronically decreased GFR and cardiovascular risk in living kidney donors/'
A X Garg
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQO0ED

Block randomized trial evidencing lower mortality with sevelamer compared with calcium phosphate binder in incident dialysis patients
J Mansour, I Shahapuni, N El Esper and A Fournier
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQP0EE

/`Too-early/' initiation of dialysis?
S Hirsch
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQQ0EF

Response to /`[thinsp]/`Too-early/' initiation of dialysis?/'
A Asif and B Bhimani
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQR0EG

Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease
B L Jaber
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQS0EH

Response to /`Bertram Jaber's letter to the editor/'
R Agarwal
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQT0EI

Gabapentin as a therapeutic option in uremic pruritus
L Manenti, A Vaglio and P P Borgatti
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQU0EJ

Response to /`Gabapentin as a therapeutic option in uremic pruritus/'
S R Keithi-Reddy and A K Singh
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQV0EK

----------------------
MAKE YOUR DIAGNOSIS
----------------------
The Case [mid] Full moon and new moon
K-L Liu, S-C Chueh, W-J Lee, K-H Huang and S-J Chen
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQW0EL

----------------------
NEPHROLOGY IMAGE
----------------------
Myeloma cast nephropathy, direct renal infiltration by myeloma, and renal extramedullary hematopoiesis
S H Nasr, B B Alobeid, J A Otrakji and G S Markowitz
http://ealerts.nature.com/cgi-bin24/DM/y/eitP0Xztnp0Hiy0BmQX0EM

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Wednesday, January 30, 2008

ABC SCIENCE UPDATES, January 31 2008

== ABC SCIENCE UPDATES, January 31 2008 ==

Science Updates is a weekly email alert from the Australian Broadcasting Corporation (ABC)

==SUMMER FLOOD AND STORM PHOTOS WANTED ==
Did you home town get hit by one of the many summer storms? Were you stranded on holidays because of flooding? Got some great photos of the experience? Send us your pics and we'll put the best ones in our online photo gallery.
http://www.abc.net.au/science/scribblygum/yourphotos/submit.htm

== TOP STORIES FROM NEWS IN SCIENCE == http://www.abc.net.au/science/news/

EXPERTS WARN OF CANNABIS CANCER EPIDEMIC
Smoking a joint is equivalent to 20 cigarettes in terms of lung cancer risk, say researchers, warning of an "epidemic" of lung cancers linked to cannabis.
http://www.abc.net.au/science/articles/2008/01/30/2150087.htm

MIDDLE AGE IS TRULY DEPRESSING, SAYS STUDY
A global study on happiness shows middle age is truly miserable, although an Australian researcher says this is not necessarily so.
http://www.abc.net.au/science/articles/2008/01/30/2149965.htm

PERSONALITY-BREAST CANCER LINK DEBUNKED
The idea that a woman's personality traits can make her more prone to breast cancer appears nothing more than a myth, say Dutch researchers
http://www.abc.net.au/science/articles/2008/01/30/2150284.htm

THICK CLOUDS CAST SHADOWS OVER MARS
Martian clouds are thick enough to cast dense shadows on the ground below and have a noticeable effect on the planet's ground temperature, say researchers.
http://www.abc.net.au/science/articles/2008/01/30/2150360.htm

== IN THE SKY THIS WEEK == http://home.mira.net/~reynella/skywatch/ssky.htm
The New Moon is Thursday February 7. There is a lot of action in the eastern morning sky. Between the 31st and Feb 2nd Venus and Jupiter come very close, and are closest on Saturday Feb 2. The morning of Saturday Feb 2, between 2-3 am, is when the waning Moon passes in front of the bright star Antares, so Saturday is a good day to rise early. The line up is joined by the crescent Moon on Monday 4 Feb and Tuesday Feb 5, making a fantastic sight. On Thursday Feb 7 there is a partial solar eclipse at around 1:30 pm. It is best seen in the eastern states, and only about 20-30% of the Sun is covered. NEVER look at the Sun with unprotected eyes, as severe eye damage may occur, use safe solar projection techniques instead. Comets Holmes can be seen with binoculars near the star Algol and comet Tuttle can be seen with binoculars not far from the star achenar. Both look like fuzzy dots.

== ABC HEALTH & WELLBEING == http://www.abc.net.au/health/

FEATURE: HELPING KIDS COPE WITH STRESS
The kids are going back to school, which for some of them will be stressful. But rather than being a cause of anxiety, many primary schools are leading the way in teaching kids to deal with life's ups and downs. And the experts say that when schools and parents work together, even sensitive kids can learn to bounce back.

http://www.abc.net.au/health/features/stories/2008/01/29/2148045.htm

== TRANSCRIPTS NOW ONLINE

SHARA BAILEY (In Conversation: 24/01/2008)

http://www.abc.net.au/rn/inconversation/stories/2008/2138910.htm

THE NEUROBIOLOGY OF SUICIDE (All In The Mind: 26/01/2008)

http://www.abc.net.au/rn/allinthemind/stories/2008/2096877.htm

HOT AND COLD ECHIDNAS (Science Show: 26/01/2008)

http://www.abc.net.au/rn/scienceshow/stories/2008/2146816.htm

BALANCING NATURE: AUSTRALIA (Science Show: 26/01/2008)

http://www.abc.net.au/rn/scienceshow/stories/2008/2121571.htm

WIPING OUT AUSTRALIAN SPECIES (Science Show: 26/01/2008)

http://www.abc.net.au/rn/scienceshow/stories/2008/2145445.htm

TROPICAL GLACIERS AND GLOBAL WARMING (Science Show: 26/01/2008)

http://www.abc.net.au/rn/scienceshow/stories/2008/2145406.htm

== COMING UP ON ABC RADIO == http://www.abc.net.au/science/programs/

SCIENCE SHOW - Balancing Nature - Part 2 Vietnam
Saturday 2 February, 12.05pm & Monday 4 February, 7.05pm RN
Lynne Malcolm visits the remote mountainous jungles of the Annamites in the heart of Vietnam. Aside from recent discoveries of new orchids, butterflies, and snakes several new mammal species have been discovered such as the antelope-like saola , the large antlered muntjac and several doucs or 5 coloured monkeys. Yet this population of threatened species is at risk from illegal logging, hunting and conflicting development as the country pushes to become a civilised society by 2020. We hear how local forest communities are working with the Forest Protection Department and NGOs to sustainably manage forest resources.

http://www.abc.net.au/rn/scienceshow/

ALL IN THE MIND - The psychological power of forgiveness in South Africa
Saturday 2 February, 1.05pm, & Monday 4 February, 1.05pm RN
Psychologist Pumla Gobodo-Madikizela was on South Africa's historic Truth and Reconciliation Commission, chairing many of its torturous public hearings about apartheid era atrocities. In an unprecedented dialogue she met with one of apartheid's most abhorrent killers, in jail, to explore forgiveness, psychological redemption and the symbolic language of trauma. She joins Natasha Mitchell in a feature interview.
http://www.abc.net.au/rn/allinthemind/

THE PHILOSOPHER'S ZONE - The emergence of science
Saturday 2 February, 1.30pm, & Monday 4 February, 1.35pm RN
In the twenty-first century, science doesn't just explain the world: it dominates the world. Religion, art, human relationships, history - we expect them all to be explained in scientific terms. How did science acquire this dominance over our way of thinking? Today, in the first episode of a two-part special, we examine the rise of science in the western mind.

http://www.abc.net.au/rn/philosopherszone/default.htm

OCKHAM'S RAZOR - Is the book dead?
Sunday 3 February, 8.45am RN
Many people have predicted the death of the book as we know it as text will be stored in digital form for us to carry around and download at whim. Sydney textbook and general science writer Peter Macinnis, having just published another book says, no. He used technology to help him research and create it but maintains the printed page is still a very important tool in schools and absolutely essential for teaching reading and writing skills.

http://www.abc.net.au/rn/ockhamsrazor/

INNOVATIONS
Sunday 3 February (0830hrs UT), Monday 4 February (1330 & 1705hrs UT), Wednesday 6 February (0430hrs UT), Radio Australia
A helmet designed to reduce motorcycle fatalities and injuries; a device that changes the way we use media and, we meet one of Australia's most celebrated medical scientists and humanitarians.
http://www.abc.net.au/ra/innovations/

HEALTH REPORT - The knee files - part one
Monday 4 February, 8.30am and 8.05pm RN
This week on The Health Report part one of two special reports on your knees and the most common form of arthritis, osteoarthritis. Are you worried that your exercise program is hurting your knees? Ever wondered what happens to knees that have run 150,000 kilometres? In program one of this series we sort the myths from the evidence about what causes knee arthritis and which of the common treatments really work. There's all the information you need to know about the effects of lifestyle factors and the latest drug treatments.
http://www.abc.net.au/rn/healthreport/

IN CONVERSATION - Don's possums
Thursday 7 February, 7.35pm RN
Professor of Zoology Don Bradshaw is now retired but continues his lifelong study of the thumb sized Honey Possum - the tiny native marsupial which depends entirely on the nectar of specific wildflowers of Western Australia. As he explains to Lynne Malcolm at his field site in Scott National Park, his passion, beyond the possum is to protect the unique Western Australian habitats which support some of the most biodiverse natural life on the planet.

http://www.abc.net.au/rn/inconversation/

== HIGHLIGHTS ON ABC TV == http://www.abc.net.au/science/programs/

KILLER ICE
Tuesday 5 February, 8.30pm
This documentary investigates the varied ways in which ice creates problems - and spawns disaster. It takes us into icy realms to survey the splendours and unlocks the mysteries of ice, and tells stories of ice's destructive and sometimes deadly nature.

NEW INVENTORS - Returns!
Wednesday 6 February, 8pm
ABC TV's highly popular The New Inventors returns for a fifth spectacular season of uncovering the brightest ideas from new and young Australian inventors
http://www.abc.net.au/tv/newinventors/

SLEEK GEEKS - Water
Thursday 7 February, 8pm
Karl and Adam look at the fundamental nature of ice and how it's unusual properties enabled life to begin. More important still is discovering the best way to keep beer cool in an esky and savouring the exotic delights of Adam's urine and bathwater
http://www.abc.net.au/science/sleekgeeks/

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