World Stem Cell Summit 2010
Monday, November 3, 2008
Latest PhD Studentships - 4 November 2008
Welcome to the FindAPhD weekly Newsletter. Listed below are the latest research projects to be advertised on FindAPhD.com.
University of Glasgow
Functional Genomic Analysis of Positional and Functional Candidate Genes for Hypertension in the SHRSP
University of Glasgow
Male predominance of gastric adenocarcinomas: Is chronic gastric inflammation leading to immunosenescence in a gender-specific manner?
University of Glasgow
Investigation of interacting blood pressure loci by congenic breeding strategies in the SHRSP rat.
University of Bath
Educational and Social Psychology
University of Glasgow
Multimarker approach for diagnosis of cardiovascular disease
University of Bath
Social-emotional processing in typical controls and psychiatric populations.
University of Glasgow
Implementation of novel contrast-enhanced cardiac magnetic resonance imaging techniques in small animal models of cardiovascular disease.
University of Glasgow
Cellular electrophysiological mechanisms of atrial fibrillation: a "dynamic-clamp" study of human atrial cells.
University of Edinburgh
DNA repair: How do cells deal with dead-end protein-DNA complexes?
University of East Anglia
Air-sea OVOC fluxes: seawater sources, sinks and role of the microlayer
University of Warwick
The impact of innovative early interventions on infant and family wellbeing
University of Durham
Communicating the Gospel in a Digital Age orBiblical Literacy in a Digital Age
University of Nottingham
Department of Mechanical, Materials & Manufacturing EngineeringPhD StudentshipAdvanced Composite Materials
University of Warwick
The impact of new generation visualisation technology on professional and lay perceptions of health
Swansea University
Development of Evolutionary based Techniques with Applications to Engineering Optimization
Many more projects have been added this week! Click here to view them all!
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The FindAPhD.com Team
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HSC Support: Blueberries and MSC
Nature Cell Biology contents: November 2008 Volume 10 Number 11, pp 1233 - 1371
NATURE CELL BIOLOGY
November 2008 Volume 10 Number 11, pp 1233 - 1371
Visit Nature Cell Biology online to browse the journal.
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----------------------
EDITORIAL
----------------------
Colouring in cells p1233
This year's Nobel Prizes mark the most significant technological advance
in cell biology, GFP et al., as well as two discoveries in virology with major
health implications.
doi:10.1038/ncb1108-1233
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXX0EW
----------------------
BOOK REVIEW
----------------------
Gray's Anatomy for worms p1234
Jonathan Hodgkin reviews C. elegans Atlas by David H. Hall and Zeynep F. Altun
doi:10.1038/ncb1108-1234
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXY0EX
----------------------
CORRESPONDENCE
----------------------
UCPs - unlikely calcium porters pp1235 - 1237
Paul S. Brookes et al.
doi:10.1038/ncb1108-1235
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXZ0EY
UCP2/3 - likely to be fundamental for mitochondrial Ca2+
uniport pp1237 - 1240
Michael Trenker, Ismene Fertschai, Roland Malli and Wolfgang F. Graier
doi:10.1038/ncb1108-1237
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXa0Ef
----------------------
REVIEW
----------------------
DNA damage and ageing: new-age ideas for an age-old problem
pp1241 - 1247
George A. Garinis, Gijsbertus T.J. van der Horst, Jan Vijg and
Jan H.J. Hoeijmakers
doi:10.1038/ncb1108-1241
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXb0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXc0Eh
----------------------
NEWS AND VIEWS
----------------------
On your MARKS, get SET, METHYLATE! pp1249 - 1250
Trans-tail regulation is the linked post-translational modification
of tails on different histones. Two important studies implicate Swd2
as the link between H2B ubiquitylation and H3 methylation. Swd2
is a component of both the SET1 methyltransferase complex and
the cleavage and polyadenylation factor CPF, implicating trans-tail
regulation in differentiating events at the beginning and end of genes.
Jane Mellor
doi:10.1038/ncb1108-1249
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXd0Ei
Bad hair days for mouse PCP mutants pp1251 - 1253
Mammalian hairs have characteristic patterns of orientation, with a
predominantly rostral to caudal direction, occasional swirls and a high
level of local correlation between hairs. A detailed new study
demonstrates that the polarity of hairs derives from an underlying planar
polarity of the basal epidermal cells from which hair follicles arise.
Jeffrey D. Axelrod
doi:10.1038/ncb1108-1251
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXe0Ej
A new dawn for Aurora? pp1253 - 1254
The balance between proliferation and differentiation is essential not
only for the generation and maintenance of tissues, but also to prevent
uncontrolled cell division and tumorigenesis. The mitotic kinase Aurora A
coordinates cell-cycle events and asymmetric division by regulating
localization of the cell fate determinant Numb through remodelling of
the conserved PAR polarity complex.
Andrea H. Brand
doi:10.1038/ncb1108-1253
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXf0Ek
----------------------
RESEARCH HIGHLIGHTS
----------------------
Research highlights p1255
Nathalie Le Bot, Silvia Grisendi, Christina Karlsson Rosenthal and
Sowmya Swaminathan
doi:10.1038/ncb1108-1255
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXg0El
----------------------
ARTICLES
----------------------
Planar polarization in embryonic epidermis orchestrates global asymmetric
morphogenesis of hair follicles pp1257 - 1268
Mammalian hair follicles are aligned along the anterior-posterior axis.
The planar cell polarity genes Vangl2 and Celsr1 are essential for hair
follicle polarization and orientation.
Danelle Devenport and Elaine Fuchs
doi:10.1038/ncb1784
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXh0Em
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXi0En
KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator
Rab3 occurs in a GTP-dependent manner through DENN/MADD pp1269 - 1279
The large, multi-functional protein DENN/MADD is an important linker
between Rab3 and the kinesin-3 motor proteins KIF1Bbeta and KIF1A in
the transport of synaptic vesicle precursors.
Shinsuke Niwa, Yosuke Tanaka and Nobutaka Hirokawa
doi:10.1038/ncb1785
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXj0Eo
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXk0Ep
Epigenetic restriction of embryonic cell lineage fate by methylation
of Elf5 pp1280 - 1290
A genome-wide screen reveals that the transcription factor Elf5 is
epigenetically silenced in the embryonic cell lineage and that its
expression is restricted to the trophoblast, where it creates a
positive-feedback loop with Cdx2 and Eomes.
Ray Kit Ng et al.
doi:10.1038/ncb1786
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXl0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXm0Er
A model for transmission of the H3K27me3 epigenetic mark
pp1291 - 1300
The chromatin mark H3K27me3 is transmitted during cell division
by recruitment and binding of the PRC2 complex, which maintains
the mark and leads to methylation of H3K27 on newly incorporated histones.
Klaus H. Hansen et al.
doi:10.1038/ncb1787
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXn0Es
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXo0Et
----------------------
LETTERS
----------------------
Actin-driven chromosomal motility leads to symmetry breaking in mammalian
meiotic oocytes pp1301 - 1308
In mammalian oocytes, cell polarity is established when meiosis I
chromosomes move from the egg centre to the cortex. This translocation
is dependent on actin filaments trailing behind the chromosomes, and on
the actin-nucleating activity of the formin Fmn2.
Hongbin Li, Fengli Guo, Boris Rubinstein and Rong Li
doi:10.1038/ncb1788
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXp0Eu
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXq0Ev
IAPs contain an evolutionarily conserved ubiquitin-binding domain that
regulates NF-kappaB as well as cell survival and oncogenesis
pp1309 - 1317
A ubiquitin binding domain in the IAP proteins binds Lys 63-linked
poly-ubiquitin chains and is essential for the oncogenic potential of
cIAP. This domain is also required for activating NF-kappaB, possibly
by binding poly-ubiquitinated NEMO.
Mads Gyrd-Hansen et al.
doi:10.1038/ncb1789
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXr0Ew
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXs0Ex
The TBP-PP2A mitotic complex bookmarks genes by preventing condensin
action pp1318 - 1323
The general transcription factor TATA-binding protein (TBP) is retained at
gene promoters during mitosis, where it recruits PP2A to inactivate condensin.
Chromatin decondensation at promoters may be associated with gene
bookmarking, a mechanism to re-establish gene activity patterns in daughter cells.
Hongyan Xing, Nathan L. Vanderford and Kevin D. Sarge
doi:10.1038/ncb1790
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXt0Ey
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXu0Ez
Formation of stress granules inhibits apoptosis by suppressing
stress-responsive MAPK pathways pp1324 - 1332
Stress-induced MAPK-dependent apoptosis is inhibited by the formation
of stress granules, which sequester and inactivate the MTK1 activator RACK1.
Kyoko Arimoto et al.
doi:10.1038/ncb1791
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXv0E1
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXw0E2
Tethering by lamin A stabilizes and targets the ING1 tumour suppressor
pp1333 - 1340
ING proteins bind to lamin A. ING1 expression and localization is perturbed
in lamin A-null cells. Data from Hutchinson-Gilford progeria syndrome (HGPS)
cells, which carry mutations in lamin A, suggest that loss of lamin A-ING
interaction may contribute to the HGPS phenotype.
Xijing Han et al.
doi:10.1038/ncb1792
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXx0E3
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXy0E4
Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid
and epidermal progenitor hyperproliferation pp1341 - 1348
Abnormal relocalization of A-type lamins to the nuclear envelope in
LAP2alpha-deficient mice impairs pRb-mediated regulation of progenitor
cell proliferation and differentiation in highly regenerative tissues.
Nana Naetar et al.
doi:10.1038/ncb1793
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAXz0E5
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX10Er
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a
pre-metastatic phase pp1349 - 1355
The production of chemoattractants in the pre-metastatic lung can be induced
by distant primary tumours. The chemoattractants S100A8 and S100A9 induce
serum amyloid A3 and TLR4 activation and cause an inflammation-like state
that facilitates metastasis.
Sachie Hiratsuka et al.
doi:10.1038/ncb1794
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX20Es
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX30Et
Scaffolding function of PAK in the PDK1-Akt pathway pp1356 - 1364
In a kinase-independent manner, PAK1 serves as a scaffold that regulates
Akt recruitment to the membrane and its stimulation by PDK1, thus regulating
efficiency, localization and specificity of the PDK-Akt pathway.
Maiko Higuchi, Keisuke Onishi, Chikako Kikuchi and Yukiko Gotoh
doi:10.1038/ncb1795
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX40Eu
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX50Ev
Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation
to H3K4 trimethylation pp1365 - 1371
Mono-ubiquitylation of histone H2B is required for methylation of histone
H3K4. Ubiquitylation of H2B in turn promotes ubiquitylation of Swd2,
a component of the SET1/COMPASS methyltransferase. Inhibiting Swd2
ubiquitylation impairs recruitment of the COMPASS subunit, which is
essential for methylation, and results in reduced H3K4 methylation.
Adeline Vitaliano-Prunier et al.
doi:10.1038/ncb1796
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX60Ew
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX70Ex
----------------------
CORRIGENDUM
----------------------
Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport
p1371
Michael Trenker et al.
doi:10.1038/ncb1108-1371
http://ealerts.nature.com/cgi-bin24/DM/y/eobF0Xztnp0HjD0CAX80Ey
=====================================================================
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EMBO Reports Table of Contents November 2008 Volume 9, Number 11, pp 1055-1155
EMBO REPORTS TABLE OF CONTENTS
November 2008 Volume 9 Number 11, pp 1055-1155
(c) Copyright 2008 by the European Molecular Biology Organization
Now available at http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60rc0EO
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Contents: Volume 9, Number 11 (November 2008)
---------------------
EDITORIAL
---------------------
Energy and biologists.
Frank Gannon
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8wx0Eq
---------------------
SCIENCE AND SOCIETY
---------------------
VIEWPOINTS
Towards preventive medicine. High-throughput methods from molecular biology are about to change daily clinical practice.
Hrvojka Bosnjak, Kresimir Pavelic & Sandra Kraljevic Pavelic
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8wy0Er
The future of agriculture. Agricultural knowledge for economically, socially and environmentally sustainable development.
Marta G Rivera-Ferre
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8wz0Es
ANALYSES
It's life, but just as we know it.
Mark Greener
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w10Ef
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w20Eg
To sleep, perchance to live. Sleeping is vital for health, cognitive function, memory and long life.
Philip Hunter
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w30Eh
Healing beauty? More biotechnology cosmetic products that claim drug-like properties reach the market.
Andrea Rinaldi
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w40Ei
---------------------
REVIEWS
---------------------
MEETING REPORT
Invasion and metastasis: stem cells, screens and survival. Conference on Invasion and Metastasis.
Nicolas Tapon & Ulrike Ziebold
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w50Ej
LITERATURE REPORT
Yeast Pol II start-site selection: the long and the short of it.
Jeffry L Corden
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w60Ek
CONCEPT
The emerging role of splicing factors in cancer.
Ana Rita Grosso, Sandra Martins & Maria Carmo-Fonseca
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w70El
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8w80Em
REVIEW
The expanding field of poly(ADP-ribosyl)ation reactions. `Protein Modifications: Beyond the Usual Suspects' Review Series.
Antoinette Hakmé, Heng-Kuan Wong, Francoise Dantzer & Valérie Schreiber
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xA0Ew
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xB0Ex
---------------------
SCIENTIFIC REPORTS
---------------------
Structural insight into the inhibition of tubulin by vinca domain peptide ligands.
Anthony Cormier, Matthieu Marchand, Raimond B G Ravelli, Marcel Knossow & Benoit Gigant
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xC0Ey
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xD0Ez
The zinc-binding protein Hot13 promotes oxidation of the mitochondrial import receptor Mia40.
Nikola Mesecke, Karl Bihlmaier, Barbara Grumbt, Sebastian Longen, Nadia Terziyska, Kai Hell & Johannes M Herrmann
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xE0E1
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xF0E2
Plasticity of Drosophila Stat DNA binding shows an evolutionary basis for Stat transcription factor preferences.
María Luisa Rivas, Laura Cobreros, Martin P Zeidler & James Castelli-Gair Hombría
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xG0E3
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xH0E4
Processive kinesins require loose mechanical coupling for efficient collective motility.
Peter Bieling, Ivo A Telley, Jacob Piehler & Thomas Surrey
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xI0E5
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xJ0E6
Novel function of the class I bHLH protein Daughterless in the negative regulation of proneural gene expression in the Drosophila eye.
Janghoo Lim, Hamed Jafar-Nejad, Ya-Chieh Hsu & Kwang-Wook Choi
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xK0E7
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xL0E8
Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Jens Radzimanowski, Bernd Simon, Michael Sattler, Konrad Beyreuther, Irmgard Sinning & Klemens Wild
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xM0EA
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xN0EB
Selective role of calcineurin in haematopoiesis and lymphopoiesis.
Elena M Gallo, Lena Ho, Monte M Winslow, Tracy L Staton & Gerald R Crabtree
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xO0EC
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xP0ED
Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition.
Kovilen Sawmynaden, Savvas Saouros, Nikolas Friedrich, Jan Marchant, Peter Simpson, Boris Bleijlevens, Michael J Blackman, Dominique Soldati-Favre & Stephen Matthews
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xQ0EE
http://ealerts.nature.com/cgi-bin24/DM/y/eoUB0Xztnp0Hh60B8xR0EF
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Cell Research Table of Contents alert Volume 18 Issue 11
CELL RESEARCH
November 2008 Volume 18 Number 11, pp 1081 - 1156
----------------------------------------------------------------------
Special Focus on Glycobiology of the Immune System
brought to you by Immunology & Cell Biology
Bringing you the latest on the glycobiology of the immune system, this
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Published 12 times a year, Cell Research is an excellent source for
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----------------------
RESEARCH HIGHLIGHTS
----------------------
Towards a comprehensive catalog of chloroplast proteins and their
interactions
Dario Leister and Tatjana Kleine
http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaT0E8
Projection of an immunological self shadow to developing T cells via
macroautophagy
Christian Munz
http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaU0EA
----------------------
REVIEW
----------------------
FXR: a metabolic regulator and cell protector
Yan-Dong Wang, Wei-Dong Chen, David D Moore and Wendong Huang
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaV0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaW0EC
----------------------
ORIGINAL ARTICLES
----------------------
Negative feedback regulation of cellular antiviral signaling by
RBCK1-mediated degradation of IRF3
Min Zhang, Yang Tian, Rui-Peng Wang, Dong Gao, Yan Zhang, Fei-Ci Diao,
Dan-Ying Chen, Zhong-He Zhai and Hong-Bing Shu
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaX0ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaY0EE
PLP2, a potent deubiquitinase from murine hepatitis virus, strongly
inhibits cellular type I interferon production
Dahai Zheng, Gang Chen, Beichu Guo, Genhong Cheng and Hong Tang
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaZ0EF
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaa0EM
A large-scale functional approach to uncover human genes and pathways
in Drosophila
Rong Xu, Kejing Deng, Yi Zhu, Yue Wu, Jing Ren, Min Wan, Shouyuan
Zhao, Xiaohui Wu, Min Han, Yuan Zhuang and Tian Xu
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAab0EN
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAac0EO
Identification of novel sense and antisense transcription at the TRPM2
locus in cancer
Ugo Orfanelli, Ann-Kathrin Wenke, Claudio Doglioni, Vincenzo Russo,
Anja Katrin Bosserhoff and Giovanni Lavorgna
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAad0EP
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAae0EQ
Estrogen deficiency leads to telomerase inhibition, telomere
shortening and reduced cell proliferation in the adrenal gland of mice
Sharyn Bayne, Margaret EE Jones, He Li, Alex R Pinto, Evan R Simpson
and Jun-Ping Liu
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAaf0ER
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAag0ES
----------------------
LETTERS TO THE EDITOR
----------------------
Enhancement of memory function in aged mice by a novel derivative of
xanomeline
Yihui Cui, Dong Wang, Wen Si, Wen Lv, Yan Niu, Xiaoping Lei, Yinhe Hu
and Xiaohua Cao
http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAah0ET
Balance of adiponectin and leptin modulates breast cancer cell growth
Michael E Grossmann, Amitabha Ray, Soner Dogan, Nancy K Mizuno and
Margot P Cleary
http://ealerts.nature.com/cgi-bin24/DM/y/eobq0Xztnp0Hhw0CAai0EU
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Nature Clinical Practice Neurology - Table of Contents alert Volume 4 Issue 11
NATURE CLINICAL PRACTICE NEUROLOGY
November 2008 Volume 4 Number 11
Visit Nature Clinical Practice Neurology online to browse the journal.
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Nature Insights Neuropsychiatric disease
This Insight highlights recent progress made in our understanding of
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----------------------
EDITORIAL
----------------------
Cocaine-associated stroke: some new insights?
Sebastian Koch and Ralph L Sacco
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZi0EC
----------------------
RESEARCH HIGHLIGHTS
----------------------
A potential new drug target for the treatment of schizophrenia
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZj0ED
Fatty acids do not reduce cognitive decline but might protect against
stroke
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZk0EE
Response to antidepressants is linked to TrkB signaling in forebrain
progenitor neurons
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZl0EF
Is antifibrinolytic therapy beneficial after aneurysmal subarachnoid
hemorrhage?
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZm0EG
Stimulation of the subthalamic nucleus targets specific motor symptoms
in Parkinson disease
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZn0EH
Generation of motor neurons from skin fibroblasts of a patient with ALS
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZo0EI
Amyloid load has a role in dementia with Lewy bodies
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZp0EJ
AMPA receptor endocytosis is a potential target in heroin addiction
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZq0EK
In briefs
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZr0EL
----------------------
PRACTICE POINTS
----------------------
Pitfalls of diagnostic criteria for small fiber neuropathy
Stephan A Botez and David N Herrmann
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZs0EM
How effective is intravenous immunoglobulin for the treatment of
relapsing-remitting multiple sclerosis?
Jeffrey A Cohen
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZt0EN
Long-term outcome in Parkinson disease: no advantage to initiating
therapy with dopamine agonists
Kathleen M Shannon
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZu0EO
The Boston Acute Stroke Imaging Scale: ready for use in clinical practice?
Jose G Merino and Lawrence L Latour
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZv0EP
Duloxetine and pregabalin: safe and effective for the long-term treatment
of fibromyalgia?
Eric Serra
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZw0EQ
Red flags to spot the parkinsonian variant of multiple system atrophy
Theresa A Zesiewicz, Kelly L Sullivan and Clifton L Gooch
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZx0ER
----------------------
VIEWPOINT
----------------------
Withdrawal of antiepileptic drugs in seizure-free patients: chance or
jeopardy?
Alla B Guekht
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZy0ES
----------------------
REVIEWS
----------------------
Mitochondrial biology and oxidative stress in Parkinson disease
pathogenesis
Claire Henchcliffe and M Flint Beal
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZz0ET
The mortality and morbidity of febrile seizures
Manoj Chungath and Simon Shorvon
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZ10EG
----------------------
CASE STUDIES
----------------------
A case of cocaine-induced basilar artery thrombosis
Clare MacEwen, Mike Ward and Alastair Buchan
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZ20EH
BOLD-MRI cerebrovascular reactivity findings in cocaine-induced cerebral
vasculitis
Jay S Han, Daniel M Mandell, Julien Poublanc, Alexandra Mardimae,
Marat Slessarev, Cheryl Jaigobin, Joseph A Fisher and David J Mikulis
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZ30EI
----------------------
TRAINING MATTERS
----------------------
The new pain curriculum: a guide for neurologists who teach
Beth Murinson and Jason Rosenberg
http://ealerts.nature.com/cgi-bin24/DM/y/eobS0Xztnp0HjL0CAZ40EJ
=====================================================================
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Each month, join us as we delve into the latest research on the brain,
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Sunday, November 2, 2008
Nature Clinical Practice Gastroenterology & Hepatology - Table of Contents alert Volume 5 Issue 11
NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY
November 2008 Volume 5 Number 11
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----------------------
EDITORIAL
----------------------
Conflicts
Stephen B Hanauer
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQm0EO
----------------------
RESEARCH HIGHLIGHTS
----------------------
Risks associated with MRSA and VRE colonization of a liver transplant
population
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQn0EP
Liver transplantation: treating recurrent hepatitis C after steroid-free
immunosuppression
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQo0EQ
A multimedia-based information program enhances the informed consent
process
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQp0ER
Increased risk of new onset IBS in individuals with a history of a biliary
event
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQq0ES
Role for pH-impedance tests in patients with GERD symptoms but no evidence
of acid reflux
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQr0ET
Accuracy of prognostic models for cirrhosis is improved by use 48 h after
admission
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQs0EU
Inlet patch: prevalence and associated upper gastrointestinal endoscopic
findings
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQt0EV
Green tea extract improves glycated hemoglobin levels
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQu0EW
Nonalcoholic fatty liver disease is a risk factor for CKD in patients
with type 2 diabetes
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQv0EX
----------------------
PRACTICE POINTS
----------------------
Who should receive antibiotic prophylaxis before ERCP?
Jacques Deviere
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQw0EY
Is once-daily dosing of mesalazine effective for maintenance of remission
in patients with ulcerative colitis?
Chris SJ Probert
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQx0EZ
Is surgery required for patients with intraductal papillary mucinous
neoplasms without mural nodules?
Ralph H Hruban and Richard D Schulick
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQy0Ea
How effective is the low-pressure adjustable gastric band for long-term
treatment of obesity?
Franz Aigner
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQz0Eb
Is probiotic prophylaxis worthwhile in patients with predicted severe
acute pancreatitis?
Stig Bengmark
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ10EO
Does long-term PPI use result in vitamin B12 deficiency in elderly
individuals?
TS Dharmarajan and Edward P Norkus
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ20EP
----------------------
VIEWPOINTS
----------------------
What is the best first-line therapy for Helicobacter pylori infection?
Xavier Calvet
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ30EQ
What is the best salvage therapy for patients with Helicobacter pylori
infection?
Lorenzo Fuccio, Rocco Maurizio Zagari and Franco Bazzoli
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ40ER
----------------------
REVIEWS
----------------------
Interferon-based therapy for chronic hepatitis C: current and future
perspectives
Stefan Zeuzem
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ50ES
Complementary and alternative medicine for IBS in adults: mind-body
interventions
David J Kearney and Janelle Brown-Chang
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ60ET
Mechanisms of infectious diarrhea
Udayakumar Navaneethan and Ralph A Giannella
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ70EU
The current role of laparoscopic liver resection for the treatment of
liver tumors
Carlo Pulitano and Luca Aldrighetti
http://ealerts.nature.com/cgi-bin24/DM/y/eoYo0Xztnp0HjJ0CAQ80EV
=====================================================================
Metabolic Syndrome - now affecting over 25% of the world's population
The 'Metabolic Syndrome 2008' web focus showcases a collection of
original research articles from our Academic and Clinical Practice
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8 distinguished titles, 16 insightful articles, one growing epidemic.
View 'Metabolic Syndrome 2008' online FREE of charge at
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