March 2010 Volume 17 Number 3, pp 295 - 438
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Gene Therapy
Editors:
J Glorioso, USA
N Lemoine, UK
At the forefront of medicine, Gene Therapy brings you the latest research
into genetic and cell-based technologies to treat disease.
Submit a paper to Gene Therapy
http://links.ealert.nature.com/ctt?kn=14&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
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REVIEW
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Progress and prospects: immune responses to viral vectors
S Nayak and R W Herzog
Abstract: http://links.ealert.nature.com/ctt?kn=4&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=47&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
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ORIGINAL ARTICLES
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Intramyocardial transplantation of fibroblasts expressing vascular
endothelial growth factor attenuates cardiac dysfunction
G A Goncalves, P F Vassallo, L dos Santos, I T Schettert, J S Nakamuta,
C Becker, P J F Tucci and J E Krieger
Abstract: http://links.ealert.nature.com/ctt?kn=46&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=45&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
The HSV-2 mutant [Delta]PK induces melanoma oncolysis through nonredundant
death programs and associated with autophagy and pyroptosis proteins
A G Colunga, J M Laing and L Aurelian
Abstract: http://links.ealert.nature.com/ctt?kn=55&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=53&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Functional assessment of skeletal muscle in intact mice lacking myostatin
by concurrent NMR imaging and spectroscopy
C Baligand, H Gilson, J C Menard, O Schakman, C Wary, J-P Thissen and
P G Carlier
Abstract: http://links.ealert.nature.com/ctt?kn=52&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=49&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Inhibitory efficacy of hypoxia-inducible factor 1[alpha] short hairpin RNA
plasmid DNA-loaded poly (D, L-lactide-co-glycolide) nanoparticles on
choroidal neovascularization in a laser-induced rat model
C Zhang, Y-S Wang, H Wu, Z-X Zhang, Y Cai, H-Y Hou, W Zhao, X-M Yang and J-X Ma
Abstract: http://links.ealert.nature.com/ctt?kn=59&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=58&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
RNAi-mediated knockdown of AURKB and EGFR shows enhanced therapeutic
efficacy in prostate tumor regression
M K Addepalli, K B Ray, B Kumar, R L Ramnath, S Chile and H Rao
Abstract: http://links.ealert.nature.com/ctt?kn=62&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=63&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Phase-I clinical trial of IL-12 plasmid/lipopolymer complexes for the
treatment of recurrent ovarian cancer
K Anwer, M N Barnes, J Fewell, D H Lewis and R D Alvarez
Abstract: http://links.ealert.nature.com/ctt?kn=64&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=65&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Non-virus-mediated transfer of siRNAs against Runx2 and Smad4 inhibit
heterotopic ossification in rats
T Xue, Z Mao, L Lin, Y Hou, X Wei, X Fu, J Zhang and C Yu
Abstract: http://links.ealert.nature.com/ctt?kn=66&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=68&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Dual transgene expression by foamy virus vectors carrying an endogenous
bidirectional promoter
A Andrianaki, E K Siapati, R K Hirata, D W Russell and G Vassilopoulos
Abstract: http://links.ealert.nature.com/ctt?kn=67&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=71&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Chemoprotection of human hematopoietic stem cells by simultaneous
lentiviral overexpression of multidrug resistance 1 and O6-
methylguanine-DNA methyltransferaseP140K
P Maier, I Spier, S Laufs, M R Veldwijk, S Fruehauf, F Wenz and
W J Zeller
Abstract: http://links.ealert.nature.com/ctt?kn=70&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=72&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Mechanisms controlling titer and expression of bidirectional lentiviral
and gammaretroviral vectors
T Maetzig, M Galla, M H Brugman, R Loew, C Baum and A Schambach
Abstract: http://links.ealert.nature.com/ctt?kn=34&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=35&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
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SHORT COMMUNICATIONS
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SLAM-enriched hematopoietic stem cells maintain long-term repopulating
capacity after lentiviral transduction using an abbreviated protocol
P Laje, P W Zoltick and A W Flake
Abstract: http://links.ealert.nature.com/ctt?kn=38&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=39&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Electroporation-mediated delivery of a naked DNA plasmid expressing VEGF
to the porcine heart enhances protein expression
W G Marshall, B A Boone, J D Burgos, S I Gografe, M K Baldwin, M L
Danielson, M J Larson, D R Caretto, Y Cruz, B Ferraro, L C Heller,
K E Ugen, M J Jaroszeski and R Heller
Abstract: http://links.ealert.nature.com/ctt?kn=36&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=37&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Extending the transposable payload limit of Sleeping Beauty (SB) using
the Herpes Simplex Virus (HSV)/SB amplicon-vector platform
S de Silva, M A Mastrangelo, L T Lotta, C A Burris, H J Federoff and
W J Bowers
Abstract: http://links.ealert.nature.com/ctt?kn=44&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=43&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Dystrophin restoration in skeletal, heart and skin arrector pili smooth
muscle of mdx mice by ZM2 NP-AON complexes
A Ferlini, P Sabatelli, M Fabris, E Bassi, S Falzarano, G Vattemi,
D Perrone, F Gualandi, N M Maraldi, L Merlini, K Sparnacci, M Laus,
A Caputo, P Bonaldo, P Braghetta and P Rimessi
Abstract: http://links.ealert.nature.com/ctt?kn=42&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=40&m=34693735&r=MTc2MTA1MzIyNwS2&b=2&j=Njg3ODMwMzUS1&mt=1&rt=0
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