Volume 101 Number 2
Published online 14 July 2009 (209 - 378)
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What if you could gain a clear view of the genomic aberrations that matter?
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British Journal of Cancer publishes high quality original papers and
reviews that make a significant contribution to increasing understanding
of the causes of cancer and to improving the treatment and survival of
patients.
Visit the journal online at
http://links.ealert.nature.com/ctt?kn=75&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
to view the latest research and access selected articles FREE of charge.
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Announcing the NEW British Journal of Cancer impact factor: 4.846
Journal Citation Reports, Thomson, 2008.
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REVIEW
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The opposing roles of Wnt-5a in cancer
S L McDonald and A Silver
Abstract: http://links.ealert.nature.com/ctt?kn=51&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=52&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
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CLINICAL STUDIES
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Management and prognosis of pancreatic cancer over a 30-year period
M David, C Lepage, J-L Jouve, V Jooste, M Chauvenet, J Faivre and A-M Bouvier
Abstract: http://links.ealert.nature.com/ctt?kn=98&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=105&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours
V Gregorc, A Santoro, E Bennicelli, C J A Punt, G Citterio, J N H Timmer-Bonte, F Caligaris Cappio, A Lambiase, C Bordignon and C M L van Herpen
Abstract: http://links.ealert.nature.com/ctt?kn=104&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=28&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Phase II trial of S-1 and cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer
F Ohyanagi, N Yamamoto, A Horiike, H Harada, T Kozuka, H Murakami, K Gomi, T Takahashi, M Morota, T Nishimura, M Endo, Y Nakamura, A Tsuya, T Horai and M Nishio
Abstract: http://links.ealert.nature.com/ctt?kn=15&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=117&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
All-oral combination of oral vinorelbine and capecitabine as first-line chemotherapy in HER2-negative metastatic breast cancer: an International Phase II Trial
N Tubiana-Mathieu, P Bougnoux, D Becquart, A Chan, P-F Conte, F Majois, M Espie, M Morand, N Vaissiere and G Villanova
Abstract: http://links.ealert.nature.com/ctt?kn=116&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=11&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Sunitinib and bevacizumab for first-line treatment of metastatic renal cell carcinoma: a systematic review and indirect comparison of clinical effectiveness
J S Thompson Coon, Z Liu, M Hoyle, G Rogers, C Green, T Moxham, K Welch and K Stein
Abstract: http://links.ealert.nature.com/ctt?kn=99&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=78&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Neoadjuvant chemotherapy followed by interval debulking surgery in patients with serous endometrial cancer with transperitoneal spread (stage IV): a new preferred treatment[quest]
I Vandenput, B Van Calster, A Capoen, K Leunen, P Berteloot, P Neven, Ph Moerman, I Vergote and F Amant
Abstract: http://links.ealert.nature.com/ctt?kn=40&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=8&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Factors affecting attitudes toward colorectal cancer screening in the primary care population
T Taskila, S Wilson, S Damery, A Roalfe, V Redman, T Ismail and R Hobbs
Abstract: http://links.ealert.nature.com/ctt?kn=45&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=68&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
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TRANSLATIONAL THERAPEUTICS
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Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines
T Zaremba, P Ketzer, M Cole, S Coulthard, E R Plummer and N J Curtin
Abstract: http://links.ealert.nature.com/ctt?kn=24&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=89&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis
T Koreckij, H Nguyen, L G Brown, E Y Yu, R L Vessella and E Corey
Abstract: http://links.ealert.nature.com/ctt?kn=57&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=25&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition
X Ding, A B Mohd, Z Huang, T Baba, M Q Bernardini, H K Lyerly, A Berchuck, S K Murphy, A B Buermeyer and G R Devi
Abstract: http://links.ealert.nature.com/ctt?kn=91&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=100&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
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MOLECULAR DIAGNOSTICS
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Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer
A J Ryan, S Napoletano, P A Fitzpatrick, C A Currid, N C O'Sullivan and J H Harmey
Abstract: http://links.ealert.nature.com/ctt?kn=27&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=92&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Annexin II represents metastatic potential in clear-cell renal cell carcinoma
Y Ohno, M Izumi, T Kawamura, T Nishimura, K Mukai and M Tachibana
Abstract: http://links.ealert.nature.com/ctt?kn=41&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=49&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Identification of macrophage migration inhibitory factor and human neutrophil peptides 1-3 as potential biomarkers for gastric cancer
Y Mohri, T Mohri, W Wei, Y-J Qi, A Martin, C Miki, M Kusunoki, D G Ward and P J Johnson
Abstract: http://links.ealert.nature.com/ctt?kn=87&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=5&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Isolation of tumour stem-like cells from benign tumours
Q Xu, X Yuan, P Tunici, G Liu, X Fan, M Xu, J Hu, J Y Hwang, D L Farkas, K L Black and J S Yu
Abstract: http://links.ealert.nature.com/ctt?kn=19&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=6&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Episodic Src activation in uveal melanoma revealed by kinase activity profiling
W Maat, M el Filali, A Dirks- Mulder, G P M Luyten, N A Gruis, L Desjardins, P Boender, M J Jager and P A van der Velden
Abstract: http://links.ealert.nature.com/ctt?kn=108&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=23&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells
S C Kirkland
Abstract: http://links.ealert.nature.com/ctt?kn=37&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=111&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion
X N Meng, Y Jin, Y Yu, J Bai, G Y Liu, J Zhu, Y Z Zhao, Z Wang, F Chen, K-Y Lee and S B Fu
Abstract: http://links.ealert.nature.com/ctt?kn=38&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=10&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Serum amyloid A (SAA): a novel biomarker for uterine serous papillary cancer
E Cocco, S Bellone, K El-Sahwi, M Cargnelutti, F Casagrande, N Buza, F A Tavassoli, E R Siegel, I Visintin, E Ratner, D-A Silasi, M Azodi, P E Schwartz, T J Rutherford, S Pecorelli and A D Santin
Abstract: http://links.ealert.nature.com/ctt?kn=16&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=69&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Inhibition of Akt sensitises neuroblastoma cells to gold(III) porphyrin 1a, a novel antitumour drug induced apoptosis and growth inhibition
W Li, Y Xie, R W-Y Sun, Q Liu, J Young, W-Y Yu, C-M Che, P K Tam and Y Ren
Abstract: http://links.ealert.nature.com/ctt?kn=115&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=120&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
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GENETICS AND GENOMICS
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The association between the T309G polymorphism of the MDM2 gene and sensitivity to anticancer drug is dependent on the p53 mutational status in cellular models
N Faur, L Araud, A Laroche-Clary, J Kanno, J Toutain, T Yamori, J Robert and V Le Morvan
Abstract: http://links.ealert.nature.com/ctt?kn=20&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=109&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array
D M Kweekel, N F Antonini, J W R Nortier, C J A Punt, H Gelderblom and H-J Guchelaar
Abstract: http://links.ealert.nature.com/ctt?kn=59&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=34&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Implication of replicative stress-related stem cell ageing in radiation-induced murine leukaemia
N Ban and M Kai
Abstract: http://links.ealert.nature.com/ctt?kn=29&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=56&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
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LETTERS TO THE EDITOR
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Expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer
P N Span, I D Nagtegaal and J Bussink
http://links.ealert.nature.com/ctt?kn=14&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Reply: expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer
E Korkeila, K Talvinen, P M Jaakkola, H Minn, K Syrjanen, J Sundstrom and S Pyrhonen
http://links.ealert.nature.com/ctt?kn=73&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Do we need biopsies of metastases for colorectal cancer patients[quest]
I Floriani, D Santini, V Torri, C Cremolini, A Falcone and F Loupakis
http://links.ealert.nature.com/ctt?kn=33&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
Reply: Do we need biopsies of metastases for colorectal cancer patients[quest]
M Frattini, F Molinari, P Saletti and L Mazzucchelli
http://links.ealert.nature.com/ctt?kn=58&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
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CORRIGENDUM
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Expression of the inhibitor of DNA-binding (ID)-1 protein as an angiogenic mediator in tumour advancement of uterine cervical cancers
M K Maw, J Fujimoto and T Tamaya
http://links.ealert.nature.com/ctt?kn=17&m=33632711&r=MTc2MDAwMTgxNgS2&b=2&j=NTMzODA0ODES1&mt=1&rt=0
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