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| Leading Edge |
| 1. | In This Issue Pages 383, 385 |
| 2. | Neurobiology Select Pages 387, 389 |
| Essay |
| 3. | Commonality but Diversity in Cancer Gene Fusions Pages 391-395 Terence H. Rabbitts |
| Previews |
| 4. | Rfu1: Stimulus for the Ubiquitin Economy Pages 397-398 Dieter A. Wolf, Matthew D. Petroski |
| 5. | Specifying Mouse Embryonic Germ Cells Pages 398-400 Patrick P.L. Tam, David A.F. Loebel |
| 6. | Opening Windows to the Genome Pages 400-402 Iestyn Whitehouse, Toshio Tsukiyama |
| 7. | HIV Entry Revisited Pages 402-404 Pradeep D. Uchil, Walther Mothes |
| 8. | Ure(k)a! Sirtuins Regulate Mitochondria Pages 404-406 William C. Hallows, Brian C. Smith, Susan Lee, John M. Denu |
| Minireview |
| 9. | Frodos Found: Behold the CENP-A “Ring” Bearers Pages 409-412 Barbara G. Mellone, Weiguo Zhang, Gary H. Karpen |
| Review |
| 10. | Blinded by the Light: The Growing Complexity of p53 Pages 413-431 Karen H. Vousden, Carol Prives |
| Articles |
| 11. | HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes Pages 433-444 Kosuke Miyauchi, Yuri Kim, Olga Latinovic, Vladimir Morozov, Gregory B. Melikyan |
| 12. | Mechanisms that Specify Promoter Nucleosome Location and Identity Pages 445-458 Paul D. Hartley, Hiten D. Madhani |
| 13. | RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells Pages 459-471 Jaehoon Kim, Mohamed Guermah, Robert K. McGinty, Jung-Shin Lee, Zhanyun Tang, Thomas A. Milne, Ali Shilatifard, Tom W. Muir, Robert G. Roeder |
| 14. | Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP Pages 472-484 Daniel R. Foltz, Lars E.T. Jansen, Aaron O. Bailey, John R. Yates III, Emily A. Bassett, Stacey Wood, Ben E. Black, Don W. Cleveland |
| 15. | HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres Pages 485-497 Elaine M. Dunleavy, Danièle Roche, Hideaki Tagami, Nicolas Lacoste, Dominique Ray-Gallet, Yusuke Nakamura, Yataro Daigo, Yoshihiro Nakatani, Geneviève Almouzni-Pettinotti |
| 16. | An Effector of RNA-Directed DNA Methylation in Arabidopsis Is an ARGONAUTE 4- and RNA-Binding Protein Pages 498-508 Xin-Jian He, Yi-Feng Hsu, Shihua Zhu, Andrzej T. Wierzbicki, Olga Pontes, Craig S. Pikaard, Hai-Liang Liu, Co-Shine Wang, Hailing Jin, Jian-Kang Zhu |
| 17. | Collapse of Germline piRNAs in the Absence of Argonaute3 Reveals Somatic piRNAs in Flies Pages 509-521 Chengjian Li, Vasily V. Vagin, Soohyun Lee, Jia Xu, Shengmei Ma, Hualin Xi, Hervé Seitz, Michael D. Horwich, Monika Syrzycka, Barry M. Honda, Ellen L.W. Kittler, Maria L. Zapp, Carla Klattenhoff, Nadine Schulz, William E. Theurkauf, Zhiping Weng, Phillip D. Zamore |
| 18. | Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary Pages 522-535 Colin D. Malone, Julius Brennecke, Monica Dus, Alexander Stark, W. Richard McCombie, Ravi Sachidanandam, Gregory J. Hannon |
| 19. | Disassembly of Exon Junction Complexes by PYM Pages 536-548 Niels H. Gehring, Styliani Lamprinaki, Andreas E. Kulozik, Matthias W. Hentze |
| 20. | An Inhibitor of a Deubiquitinating Enzyme Regulates Ubiquitin Homeostasis Pages 549-559 Yoko Kimura, Hideki Yashiroda, Tai Kudo, Sumiko Koitabashi, Shigeo Murata, Akira Kakizuka, Keiji Tanaka |
| 21. | SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle Pages 560-570 Takashi Nakagawa, David J. Lomb, Marcia C. Haigis, Leonard Guarente |
| 22. | A Signaling Principle for the Specification of the Germ Cell Lineage in Mice Pages 571-584 Yasuhide Ohinata, Hiroshi Ohta, Mayo Shigeta, Kaori Yamanaka, Teruhiko Wakayama, Mitinori Saitou |
| SnapShot |
| 23. | SnapShot: MicroRNAs in Cancer Pages 586-586.e1 Riccardo Spizzo, Milena S. Nicoloso, Carlo M. Croce, George A. Calin |
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