May 2009 Volume 28 Number 19, pp 2005 - 2063
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Why not take a multifaceted look at your cancer genome?
Agilent offers a single microarray platform for CGH, miRNA, gene expression,
and DNA methylation, giving you a more complete view of the disease.
So why not use a research platform capable of meeting the complexity of cancer itself,
with DNA microarrays from Agilent. Learn more at
http://links.ealert.nature.com/ctt?kn=5&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
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Attending the ASCO Annual Meeting in Orlando, FL this month?
Visit us at Booth 1563 to meet the Editors and pick up your
complimentary copy of Nature Reviews Clinical Oncology and other
related journals from Nature Publishing Group.
We hope to see you there!
http://links.ealert.nature.com/ctt?kn=27&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
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Call for papers!
Submit your best work in the field oncogenes, including mechanism of
activation, structure and function of encoded proteins; DNA and
RNA tumor viruses and all other aspects of structure and function.
Our online submission process is easy and can assist you in becoming
part of this distinguished journal. To learn about the benefits of
submitting your paper to Oncogene, visit
http://links.ealert.nature.com/ctt?kn=7&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
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ORIGINAL ARTICLES
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p53, secreted by K-Ras-Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker
S-H Lee, S-J Lee, J-Y Chung, Y-S Jung, S-Y Choi, S H Hwang, D Choi, N-C Ha and B-J Park
Abstract: http://links.ealert.nature.com/ctt?kn=16&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=12&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Galectin-1 is a major effector of TrkB-mediated neuroblastoma aggressiveness
F Cimmino, J H Schulte, M Zollo, J Koster, R Versteeg, A Iolascon, A Eggert and A Schramm
Abstract: http://links.ealert.nature.com/ctt?kn=50&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=20&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma
L M S Lau, J K Wolter, J T M L Lau, L S Cheng, K M Smith, L M Hansford, L Zhang, S Baruchel, F Robinson and M S Irwin
Abstract: http://links.ealert.nature.com/ctt?kn=10&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=6&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Artemin is oncogenic for human mammary carcinoma cells
J Kang, J K Perry, V Pandey, G C Fielder, B Mei, P X Qian, Z S Wu, T Zhu, D X Liu and P E Lobie
Abstract: http://links.ealert.nature.com/ctt?kn=42&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=51&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
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SHORT COMMUNICATION
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DNA methylation inhibits p53-mediated survivin repression
N H Nabilsi, R R Broaddus and D S Loose
Abstract: http://links.ealert.nature.com/ctt?kn=30&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=25&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
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ONCOGENOMICS
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Microarray coupled to quantitative RT-PCR analysis of androgen-regulated genes in human LNCaP prostate cancer cells
S Ngan, E A Stronach, A Photiou, J Waxman, S Ali and L Buluwela
Abstract: http://links.ealert.nature.com/ctt?kn=52&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=53&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
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Special Issue on Gene Therapy for Chronic Pain
Guest Editors: Joseph Glorioso and David Fink
Volume 16 Number 4
Chronic pain is a significant medical problem. Recent studies suggest that
employing gene transfer to release neuroactive peptides at targeted sites in
the pain pathway may be an effective means to reduce pain, while avoiding
off-target side effects that limit pharmacologic treatment. This issue surveys
results from preclinical animal studies using several different vector
technologies, and describes the first clinical trial of gene transfer for the
treatment of pain using an HSV-based vector that began enrolling patients in
December 2008.
Free content available now at http://links.ealert.nature.com/ctt?kn=37&m=32935849&r=MTc2ODI0Mjc1MwS2&b=2&j=NDk0OTU2NTQS1&mt=1&rt=0
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