Volume 100 Number 6
Published online 17 March 2009 (865 - 1020)
---------------------------------------------------------------------
Why not take a multifaceted look at your cancer genome?
Agilent offers a single microarray platform for CGH, miRNA,
gene expression, and DNA methylation, giving you a more complete
view of the disease. So why not use a research platform capable of
meeting the complexity of cancer itself, with DNA microarrays from Agilent.
Learn more at OpenGenomics.com
http://links.ealert.nature.com/ctt?kn=3&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
---------------------------------------------------------------------
British Journal of Cancer publishes high quality original papers and reviews
that make a significant contribution to increasing understanding of the causes
of cancer and to improving the treatment and survival of patients.
Visit the journal online at http://links.ealert.nature.com/ctt?kn=93&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
to view the latest research and access selected articles FREE of charge.
---------------------------------------------------------------------
British Journal of Cancer has an impact factor 4.635*
*2007 Journal Citation Report (Thomson Reuters, 2008)
----------------------
MINIREVIEW
----------------------
Why are tumour blood vessels abnormal and why is it important to know[quest]
J A Nagy, S-H Chang, A M Dvorak and H F Dvorak
Abstract: http://links.ealert.nature.com/ctt?kn=57&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=50&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
----------------------
CLINICAL STUDIES
----------------------
Homozygous CDA[ast]3 is a major cause of life-threatening toxicities in gemcitabine-treated Japanese cancer patients
H Ueno, N Kaniwa, T Okusaka, M Ikeda, C Morizane, S Kondo, E Sugiyama, S R Kim, R Hasegawa, Y Saito, T Yoshida, N Saijo and J Sawada
Abstract: http://links.ealert.nature.com/ctt?kn=44&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=35&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer
E Korkeila, K Talvinen, P M Jaakkola, H Minn, K Syrjanen, J Sundstrom and S Pyrhonen
Abstract: http://links.ealert.nature.com/ctt?kn=141&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=86&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Mucinous histology predicts for poor response rate and overall survival of patients with colorectal cancer and treated with first-line oxaliplatin- and//or irinotecan-based chemotherapy
V Catalano, F Loupakis, F Graziano, U Torresi, R Bisonni, D Mari, L Fornaro, A M Baldelli, P Giordani, D Rossi, P Alessandroni, L Giustini, R R Silva, A Falcone, S D'Emidio and S L Fedeli
Abstract: http://links.ealert.nature.com/ctt?kn=4&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=107&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Ki-67 and outcome in clinically localised prostate cancer: analysis of conservatively treated prostate cancer patients from the Trans-Atlantic Prostate Group study
D M Berney, A Gopalan, S Kudahetti, G Fisher, L Ambroisine, C S Foster, V Reuter, J Eastham, H Moller, M W Kattan, W Gerald, C Cooper, P Scardino and J Cuzick
Abstract: http://links.ealert.nature.com/ctt?kn=37&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=11&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients
Y H Park, M J Park, S H Ji, S Y Yi, D H Lim, D H Nam, J-I Lee, W Park, D H Choi, S J Huh, J S Ahn, W K Kang, K Park and Y-H Im
Abstract: http://links.ealert.nature.com/ctt?kn=68&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=79&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Inter-observer variability in mammography screening and effect of type and number of readers on screening outcome
L E M Duijm, M W J Louwman, J H Groenewoud, L V van de Poll-Franse, J Fracheboud and J W Coebergh
Abstract: http://links.ealert.nature.com/ctt?kn=81&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=146&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Hospital anxiety and depression scale cutoff scores for cancer patients in acute care
S Singer, S Kuhnt, H Gotze, J Hauss, A Hinz, A Liebmann, O Krausz, A Lehmann and R Schwarz
Abstract: http://links.ealert.nature.com/ctt?kn=122&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=52&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
A tool to balance benefit and harm when deciding about adjuvant therapy
A M Knops, A Goossens, M P M Burger, L J A Stalpers and D T Ubbink
Abstract: http://links.ealert.nature.com/ctt?kn=105&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=103&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
----------------------
TRANSLATIONAL THERAPEUTICS
----------------------
CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts
E Marangoni, N Lecomte, L Durand, G de Pinieux, D Decaudin, C Chomienne, F Smadja-Joffe and M-F Poupon
Abstract: http://links.ealert.nature.com/ctt?kn=88&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=116&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study
J Klawitter, N Anderson, J Klawitter, U Christians, D Leibfritz, S G Eckhardt and N J Serkova
Abstract: http://links.ealert.nature.com/ctt?kn=101&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=28&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
The novel Akt inhibitor Palomid 529 (P529) enhances the effect of radiotherapy in prostate cancer
R Diaz, P A Nguewa, J A Diaz-Gonzalez, E Hamel, O Gonzalez-Moreno, R Catena, D Serrano, M Redrado, D Sherris and A Calvo
Abstract: http://links.ealert.nature.com/ctt?kn=71&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=133&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR//Her2 inhibitor in non-small-cell lung cancer cells
S Agarwal, C Zerillo, J Kolmakova, J G Christensen, L N Harris, D L Rimm, M P DiGiovanna and D F Stern
Abstract: http://links.ealert.nature.com/ctt?kn=49&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=120&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies
A Diaz Miqueli, J Rolff, M Lemm, I Fichtner, R Perez and E Montero
Abstract: http://links.ealert.nature.com/ctt?kn=2&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=140&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
----------------------
MOLECULAR DIAGNOSTICS
----------------------
Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer
M Loddo, S R Kingsbury, M Rashid, I Proctor, C Holt, J Young, S El-Sheikh, M Falzon, K L Eward, T Prevost, R Sainsbury, K Stoeber and G H Williams
Abstract: http://links.ealert.nature.com/ctt?kn=19&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=82&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
The VEGF pathway and the AKT//mTOR//p70S6K1 signalling pathway in human epithelial ovarian cancer
X B Trinh, W A A Tjalma, P B Vermeulen, G Van den Eynden, I Van der Auwera, S J Van Laere, J Helleman, E M J J Berns, L Y Dirix and P A van Dam
Abstract: http://links.ealert.nature.com/ctt?kn=136&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=64&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
External validation of serum hCG cutoff levels for prediction of resistance to single-agent chemotherapy in patients with persistent trophoblastic disease
L G Kerkmeijer, C M Thomas, R Harvey, F C Sweep, H Mitchell, L F Massuger and M J Seckl
Abstract: http://links.ealert.nature.com/ctt?kn=123&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=10&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Detection of K-Ras mutations in tumour samples of patients with non-small cell lung cancer using PNA-mediated PCR clamping
M Beau-Faller, M Legrain, A-C Voegeli, E Guerin, T Lavaux, A-M Ruppert, A Neuville, G Massard, J-M Wihlm, E Quoix, P Oudet and M P Gaub
Abstract: http://links.ealert.nature.com/ctt?kn=46&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=70&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
----------------------
GENETICS AND GENOMICS
----------------------
Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer
L Quaye, H Song, S J Ramus, A Gentry-Maharaj, E Hogdall, R A DiCioccio, V McGuire, A H Wu, D J Van Den Berg, M C Pike, E Wozniak, J A Doherty, M A Rossing, R B Ness, K B Moysich, C Hogdall, J Blaakaer, D F Easton, B A J Ponder, I J Jacobs, U Menon, A S Whittemore, S Kruger-Kjaer, C L Pearce, P D P Pharoah and S A Gayther
Abstract: http://links.ealert.nature.com/ctt?kn=104&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=30&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma
H-C Chen, G-H Chen, Y-H Chen, W-L Liao, C-Y Liu, K-P Chang, Y-S Chang and S-J Chen
Abstract: http://links.ealert.nature.com/ctt?kn=100&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=87&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
----------------------
CORRIGENDA
----------------------
In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and//or chemotherapy drugs
D M Ashley, C D Riffkin, M M Lovric, T Mikeska, A Dobrovic, J A Maxwell, H S Friedman, K J Drummond, A H Kaye, H K Gan, T G Johns and C J Hawkins
http://links.ealert.nature.com/ctt?kn=32&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Human thyroid tumours, the puzzling lessons from E7 and RET//PTC3 transgenic mice
L Jin, A Burniat, J-E Dumont, F Miot, B Corvilain and B Franc
http://links.ealert.nature.com/ctt?kn=69&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Direct effects of doxorubicin on skeletal muscle contribute to fatigue
K van Norren, A van Helvoort, J M Argiles, S van Tuijl, K Arts, M Gorselink, A Laviano, D Kegler, H P Haagsman and E M van der Beek
http://links.ealert.nature.com/ctt?kn=144&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
----------------------
LETTERS TO THE EDITOR
----------------------
Hookah, opium and tobacco smoking in relation to oesophageal squamous cell carcinoma
K Chaouachi
http://links.ealert.nature.com/ctt?kn=108&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Reply: Hookah, opium, and tobacco smoking in relation to ESCC
R Malekzadeh, D Nasrollahzadeh and F Kamangar
http://links.ealert.nature.com/ctt?kn=132&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Irinotecan toxicity: genes or intestinal microflora[quest]
G Brandi, F de Rosa and G Biasco
http://links.ealert.nature.com/ctt?kn=23&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
----------------------
BOOK REVIEWS
----------------------
Gene Therapy Protocols
O Danos
http://links.ealert.nature.com/ctt?kn=40&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
Cancer neurology in clinical practice, neurological complications of cancer and its treatment (2nd Edn)
I Radovanovic and G Zadeh
http://links.ealert.nature.com/ctt?kn=92&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
---------------------------------------------------------------------
Ensure your access to British Journal of Cancer
If you are unable to access the articles in this Table of Contents e-alert,
your library may not subscribe to this journal. Our online recommendation form
is a simple way to make your librarian aware that this journal is valuable to your research.
Recommend now at http://links.ealert.nature.com/ctt?kn=59&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
=====================================================================
You have been sent this Table of Contents Alert because you have opted in to receive it.
You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at:
http://links.ealert.nature.com/ctt?kn=24&m=32035034&r=MTc2MDAwMTgxNgS2&b=2&j=NDY2MTc0NjkS1&mt=1&rt=0
(You will need to log in to be recognised as a nature.com registrant).
For further technical assistance, please contact our registration department:
registration@nature.com
For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com
For other enquiries, please contact customer feedback department:
feedback@nature.com
Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA
Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne - San Diego - San Francisco - Washington - New York - Boston
Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS.
© Copyright 2009 Nature Publishing Group
=====================================================================
