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The EMBO Journal
Table of contents
Volume 27, Number 22 (19 November 2008)
In this issue...
Clustering of VASP actively drives processive, WH2 domain-mediated
actin filament elongation
Ena/VASP proteins are key regulators of actin dynamics, yet
conflicting models on their mode of action have been put forward in
the literature. The Faix lab now reports the first evidence that VASP
delivers actin monomers to the growing barbed end, and thus possesses
processive filament elongation activity.
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnJ0Ey
A novel disulphide switch mechanism in Ero1[alpha] balances ER
oxidation in human cells
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnK0Ez
Low reduction potential of Ero1[alpha] regulatory disulphides ensures
tight control of substrate oxidation
Ero1 family members play an essential role in disulphide bond
formation in the endoplasmic reticulum (ER), but little is know about
the regulation of Ero1 activity in mammalian cells. Two studies from
the Ellgaard and Bulleid labs provide new insight into the regulation
of human Ero1[alpha], revealing a novel regulatory feedback loop in ER
redox control.
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnL0E1
Articles
Clustering of VASP actively drives processive, WH2 domain-mediated
actin filament elongation.
Dennis Breitsprecher, Antje K Kiesewetter, Joern Linkner, Claus
Urbanke, Guenter P Resch, J Victor Small and Jan Faix
The EMBO Journal (2008) 27, 22, 2943-2954
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnJ0Ey
Published online: 16 October 2008
An Id-like molecule, HHM, is a synexpression group-restricted
regulator of TGF-beta signalling.
Hiroaki Ikushima, Akiyoshi Komuro, Kazunobu Isogaya, Masahiko
Shinozaki, Ulf Hellman, Keiji Miyazawa and Kohei Miyazono
The EMBO Journal (2008) 27, 22, 2955-2965
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnM0E2
Published online: 16 October 2008
Regulation of ARE transcript 3prime end processing by the yeast Cth2
mRNA decay factor.
Manoel Prouteau, Marie-Claire Daugeron and Bertrand Séraphin
The EMBO Journal (2008) 27, 22, 2966-2976
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnN0E3
Published online: 16 October 2008
A novel disulphide switch mechanism in Ero1alpha balances ER
oxidation in human cells.
Christian Appenzeller-Herzog, Jan Riemer, Brian Christensen, Esben S
Sorensen and Lars Ellgaard
The EMBO Journal (2008) 27, 22, 2977-2987
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnK0Ez
Published online: 2 October 2008
Low reduction potential of Ero1alpha regulatory disulphides ensures
tight control of substrate oxidation.
Karl M Baker, Seema Chakravarthi, Kevin P Langton, Alyson M Sheppard,
Hui Lu and Neil J Bulleid
The EMBO Journal (2008) 27, 22, 2988-2997
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnL0E1
Published online: 30 October 2008
The IQGAP Iqg1 is a regulatory target of CDK for cytokinesis in
Candida albicans.
Chang-Run Li, Yan-Ming Wang and Yue Wang
The EMBO Journal (2008) 27, 22, 2998-3010
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnO0E4
Published online: 16 October 2008
Localization of Smc5/6 to centromeres and telomeres requires
heterochromatin and SUMO, respectively.
Stephanie Pebernard, Lana Schaffer, Daniel Campbell, Steven R Head
and Michael N Boddy
The EMBO Journal (2008) 27, 22, 3011-3023
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnP0E5
Published online: 16 October 2008
RNA-dependent recruitment of the origin recognition complex.
Julie Norseen, Andreas Thomae, Venkatesh Sridharan, Ashok Aiyar,
Aloys Schepers and Paul M Lieberman
The EMBO Journal (2008) 27, 22, 3024-3035
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnQ0E6
Published online: 23 October 2008
Rad51 suppresses gross chromosomal rearrangement at centromere in
Schizosaccharomyces pombe.
Ken-ichi Nakamura, Aya Okamoto, Yuki Katou, Chie Yadani, Takeshi
Shitanda, Chitrada Kaweeteerawat, Tatsuro S Takahashi, Takehiko Itoh,
Katsuhiko Shirahige, Hisao Masukata and Takuro Nakagawa
The EMBO Journal (2008) 27, 22, 3036-3046
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnR0E7
Published online: 16 October 2008
ASIC3, a sensor of acidic and primary inflammatory pain.
Emmanuel Deval, Jacques Noel, Nadège Lay, Abdelkrim Alloui, Sylvie
Diochot, Valérie Friend, Martine Jodar, Michel Lazdunski and Eric
Lingueglia
The EMBO Journal (2008) 27, 22, 3047-3055
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnS0E8
Published online: 16 October 2008
Gating motions underlie AMPA receptor secretion from the endoplasmic
reticulum.
Andrew C Penn, Stephen R Williams and Ingo H Greger
The EMBO Journal (2008) 27, 22, 3056-3068
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnT0EA
Published online: 16 October 2008
Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in
postnatal neuronal migration.
Sophia M Blake, Vera Strasser, Nuno Andrade, Sarah Duit, Reinhold
Hofbauer, Wolfgang J Schneider and Johannes Nimpf
The EMBO Journal (2008) 27, 22, 3069-3080
http://ealerts.nature.com/cgi-bin24/DM/y/eouW0Xztnp0Hh50CBnU0EB
Published online: 23 October 2008
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