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| Leading Edge |
| 1. | In This Issue Pages 369, 371 |
| 2. | Neurobiology Select Pages 373, 375 |
| Essays |
| 3. | Autism: Many Genes, Common Pathways? Pages 391-395 Daniel H. Geschwind |
| 4. | Autism and Brain Development Pages 396-400 Christopher A. Walsh, Eric M. Morrow and John L.R. Rubenstein |
| 5. | The Autistic Neuron: Troubled Translation? Pages 401-406 Raymond J. Kelleher III and Mark F. Bear |
| Previews |
| 6. | It Takes a (Dysfunctional) Village to Raise a Tumor Pages 408-410 Karlyne M. Reilly and Terry Van Dyke |
| 7. | Dormant Spores Receive an Unexpected Wake-up Call Pages 410-412 Peter Setlow |
| 8. | A Protein-Only RNase P in Human Mitochondria Pages 412-414 Scott C. Walker and David R. Engelke |
| 9. | Myosin Learns to Recruit AMPA Receptors Pages 414-415 Eran Perlson and Erika L.F. Holzbaur |
| Minireview |
| 10. | Knockdown Screens to Knockout HIV-1 Pages 417-420 Stephen P. Goff |
| Review |
| 11. | The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses Pages 422-435 Gina G. Turrigiano |
| Articles |
| 12. | Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/−- and c-kit-Dependent Bone Marrow Pages 437-448 Feng-Chun Yang, David A. Ingram, Shi Chen, Yuan Zhu, Jin Yuan, Xiaohong Li, Xianlin Yang, Scott Knowles, Whitney Horn, Yan Li, Shaobo Zhang, Yanzhu Yang, Saeed T. Vakili, Menggang Yu, Dennis Burns, Kent Robertson, Gary Hutchins, Luis F. Parada and D. Wade Clapp |
| 13. | The Growth Factor Environment Defines Distinct Pluripotent Ground States in Novel Blastocyst-Derived Stem Cells Pages 449-461 Yu-Fen Chou, Hsu-Hsin Chen, Maureen Eijpe, Akiko Yabuuchi, Joshua G. Chenoweth, Paul Tesar, Jun Lu, Ronald D.G. McKay and Niels Geijsen |
| 14. | RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme Pages 462-474 Johann Holzmann, Peter Frank, Esther Löffler, Keiryn L. Bennett, Christopher Gerner and Walter Rossmanith |
| 15. | The MatP/matS Site-Specific System Organizes the Terminus Region of the E. coli Chromosome into a Macrodomain Pages 475-485 Romain Mercier, Marie-Agnès Petit, Sophie Schbath, Stéphane Robin, Meriem El Karoui, Frédéric Boccard and Olivier Espéli |
| 16. | A Eukaryotic-like Ser/Thr Kinase Signals Bacteria to Exit Dormancy in Response to Peptidoglycan Fragments Pages 486-496 Ishita M. Shah, Maria-Halima Laaberki, David L. Popham and Jonathan Dworkin |
| 17. | An Assembly Chaperone Collaborates with the SMN Complex to Generate Spliceosomal SnRNPs Pages 497-509 Ashwin Chari, Monika M. Golas, Michael Klingenhäger, Nils Neuenkirchen, Bjoern Sander, Clemens Englbrecht, Albert Sickmann, Holger Stark and Utz Fischer |
| 18. | Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement Pages 510-523 Victoria Sanz-Moreno, Gilles Gadea, Jessica Ahn, Hugh Paterson, Pierfrancesco Marra, Sophie Pinner, Erik Sahai and Christopher J. Marshall |
| 19. | Undertaker, a Drosophila Junctophilin, Links Draper-Mediated Phagocytosis and Calcium Homeostasis Pages 524-534 Leigh Cuttell, Andrew Vaughan, Elizabeth Silva, Claire J. Escaron, Mark Lavine, Emeline Van Goethem, Jean-Pierre Eid, Magali Quirin and Nathalie C. Franc |
| 20. | Myosin Vb Mobilizes Recycling Endosomes and AMPA Receptors for Postsynaptic Plasticity Pages 535-548 Zhiping Wang, Jeffrey G. Edwards, Nathan Riley, D. William Provance Jr., Ryan Karcher, Xiang-dong Li, Ian G. Davison, Mitsuo Ikebe, John A. Mercer, Julie A. Kauer and Michael D. Ehlers |
| 21. | Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning Pages 549-560 Yijun Cui, Rui M. Costa, Geoffrey G. Murphy, Ype Elgersma, Yuan Zhu, David H. Gutmann, Luis F. Parada, Istvan Mody and Alcino J. Silva |
| Resource |
| 22. | Anatomical Profiling of G Protein-Coupled Receptor Expression Pages 561-571 Jean B. Regard, Isaac T. Sato and Shaun R. Coughlin |
| SnapShot |
| 23. | SnapShot: The Hormonal Control of Food Intake Pages 572.e1-572.e2 Anthony P. Coll, Giles S.H. Yeo, I. Sadaf Farooqi and Stephen O'Rahilly |
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