Genetically Modified Stem Cells

View this message online Hello manoj kumar valluru, A paper was published last week in which adult bone marrow mesenchymal stem cells were transfected with the IGF-1 gene and used to treat animals after cardiac infarction.  Animals treated with the genetically modified stem cells exhibited better recovery as compared to controls recieving sham transfected cells.  Most interestingly, the authors demonstrated that the protective effect was associated with mobilization of endogenous stem cells.  2 patents of interest to our field were recently issued.  The first #7,439,332 teaches a new polypeptide that stimulates erythropoiesis.  Perhaps most interesting about this patent was how they discovered the compound.  The second #7,439,064 is another one of Jamie Thomson's masterpieces, this time disclosing a serum-free, feeder-free method of maintaining embryonic stem cells in culture without spontaneous differentation.  The broadness of the first claim will strike you.   Potentiating Mesenchymal Stem Cells for Cardiac Regeneration Sunday October 26th, 2008 @ 12:13:01 EST Cincinnati, Ohio - Mesenchymal stem cells are attractive for therapeutics development because they can theoretically be used as a "one size fits all".  Additionally, their ability to home to area of tissue injury, in part by [Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News       RMSC 2008 World Congress (2-4 December 2008) The 3rd Annual Stem Cells World Congress (20-22 January 2009) The Stem Cell Meeting (March 2009)     RECENTLY ADDED PATENTS     Cultivation of human embryonic stem cells in the absence of feeder cells or without conditioned medium (7,439,064) Assignee | Inventor | Ask a question OR leave your comments     Polypeptide having an activity to support proliferation or survival of hematopoietic stem or progenitor cells (7,439,332) Assignee | Inventor | Ask a question OR leave your comments     Compositions for allogeneic cell therapy (7,435,592) Assignee | Inventor | Ask a question OR leave your comments     CXCR4 antagonist treatment of hematopoietic cells (7,435,718) Assignee | Inventor | Ask a question OR leave your comments     Methods for the culture of human embryonic stem cells on human feeder cells (7,432,104) Assignee | Inventor | Ask a question OR leave your comments     Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions (7,431,932) Assignee | Inventor | Ask a question OR leave your comments     Vasostatin as marrow protectant (7,432,236) Assignee | Inventor | Ask a question OR leave your comments     Unactivated oocytes as cytoplast recipients for nonprimate mammalian and pig nuclear transfer (7,432,415) Assignee | Inventor | Ask a question OR leave your comments     Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion (7,429,383) Assignee | Inventor | Ask a question OR leave your comments     Methods of controlling proliferation and differentiation of stem and progenitor cells (7,429,489) Assignee | Inventor | Ask a question OR leave your comments     View all 1347 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     Potentiating Mesenchymal Stem Cells for Cardiac Regeneration 1 day ago     Sensitizing CML Precursors to GVL October 19th     Making stem cells find apoptotic cells October 8th     ES cells as immune modulators: look out MSCs !! October 5th     Cancer Vaccine Against Aurora Kinase October 2nd     Read more news on StemCellPatents.com     LATEST JOBS POSTS     Attorney- Patent Litigation Associate Crescent Strategic Resources     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com. We welcome your comments and suggestions! Tell us here. Media Partnerships (NEW) ------------------------------------------------------------ To unsubscribe, click here. Delivered: Monday October 27th, 2008 @ 15:15:08 EST