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http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yp0EE
The EMBO Journal
Table of contents
Volume 27, Number 15 (06 August 2008)
In this issue...
The Tat system proofreads FeS protein substrates and directly
initiates the disposal of rejected molecules
Only fully folded proteins are thought to be transported by the Tat
translocation system. New results from Colin Robinson's group now show
that Tat's quality control mechanism does not stop at the rejection of
misfolded substrates, but also triggers their degradation in the
cytoplasm.
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yq0EF
The DEAD-box helicase DDX3X is a critical component of the
TANK-binding kinase 1-dependent innate immune response
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yr0EG
Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKK[epsilon]
-mediated IRF activation
Setting out from different angles, these two papers by the labs of
Superti-Furga, Decker and Bowie converge on the identification of
DDX3X as a novel player in the TBK1-dependent interferon response,
thus putting forward a novel function for a DEAD box helicase in
innate immunity.
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Ys0EH
Articles
Reconstituted membrane fusion requires regulatory lipids, SNAREs and
synergistic SNARE chaperones.
Joji Mima, Christopher M Hickey, Hao Xu, Youngsoo Jun and William
Wickner
The EMBO Journal (2008) 27, 15, 2031-2042
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yt0EI
Published online: 24 July 2008
Adaptation of endoplasmic reticulum exit sites to acute and chronic
increases in cargo load.
Hesso Farhan, Matthias Weiss, Katsuko Tani, Randal J Kaufman and
Hans-Peter Hauri
The EMBO Journal (2008) 27, 15, 2043-2054
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yu0EJ
Published online: 24 July 2008
The Tat system proofreads FeS protein substrates and directly
initiates the disposal of rejected molecules.
Cristina F R O Matos, Colin Robinson and Alessandra Di Cola
The EMBO Journal (2008) 27, 15, 2055-2063
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yq0EF
Published online: 10 July 2008
Regulation of contractile vacuole formation and activity in
Dictyostelium.
Fei Du, Kimberly Edwards, Zhouxin Shen, Binggang Sun, Arturo De
Lozanne, Steven Briggs and Richard A Firtel
The EMBO Journal (2008) 27, 15, 2064-2076
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yv0EK
Published online: 17 July 2008
Extracellular Alix regulates integrin-mediated cell adhesions and
extracellular matrix assembly.
Shujuan Pan, Ruoning Wang, Xi Zhou, Joe Corvera, Malgorzata Kloc,
Richard Sifers, Gary E Gallick, Sue-Hwa Lin and Jian Kuang
The EMBO Journal (2008) 27, 15, 2077-2090
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yw0EL
Published online: 17 July 2008
Epidermal insulin/IGF-1 signalling control interfollicular
morphogenesis and proliferative potential through Rac activation.
Heike Stachelscheid, Hady Ibrahim, Linda Koch, Annika Schmitz,
Michael Tscharntke, F Thomas Wunderlich, Jeanie Scott, Christian
Michels, Claudia Wickenhauser, Ingo Haase, Jens C Brüning and Carien
M Niessen
The EMBO Journal (2008) 27, 15, 2091-2101
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yx0EM
Published online: 24 July 2008
Nuclear import of CaMV P6 is required for infection and suppression
of the RNA silencing factor DRB4.
Gabrielle Haas, Jacinthe Azevedo, Guillaume Moissiard, Angèle
Geldreich, Christophe Himber, Marina Bureau, Toshiyuki Fukuhara,
Mario Keller and Olivier Voinnet
The EMBO Journal (2008) 27, 15, 2102-2112
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yy0EN
Published online: 10 July 2008
Domain-swapped dimerization of ZO-1 PDZ2 generates specific and
regulatory connexin43-binding sites.
Jia Chen, Lifeng Pan, Zhiyi Wei, Yanxiang Zhao and Mingjie Zhang
The EMBO Journal (2008) 27, 15, 2113-2123
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yz0EO
Published online: 17 July 2008
Huntingtin phosphorylation acts as a molecular switch for
anterograde/retrograde transport in neurons.
Emilie Colin, Diana Zala, Géraldine Liot, Hélène Rangone, Maria
Borrell-Pagès, Xiao-Jiang Li, Frédéric Saudou and Sandrine Humbert
The EMBO Journal (2008) 27, 15, 2124-2134
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Y10EB
Published online: 10 July 2008
The DEAD-box helicase DDX3X is a critical component of the
TANK-binding kinase 1-dependent innate immune response.
Didier Soulat, Tilmann Bürckstümmer, Sandra Westermayer, Adriana
Goncalves, Angela Bauch, Adrijana Stefanovic, Oliver Hantschel,
Keiryn L Bennett, Thomas Decker and Giulio Superti-Furga
The EMBO Journal (2008) 27, 15, 2135-2146
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Yr0EG
Published online: 26 June 2008
Viral targeting of DEAD box protein 3 reveals its role in
TBK1/IKKepsiv-mediated IRF activation.
Martina Schroder, Marcin Baran and Andrew G Bowie
The EMBO Journal (2008) 27, 15, 2147-2157
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Ys0EH
Published online: 17 July 2008
Molecular mechanism of ligand recognition by NR3 subtype glutamate
receptors.
Yongneng Yao, Chris B Harrison, Peter L Freddolino, Klaus Schulten
and Mark L Mayer
The EMBO Journal (2008) 27, 15, 2158-2170
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Y20EC
Published online: 17 July 2008
Crystal structures of the OmpF porin: function in a colicin
translocon.
Eiki Yamashita, Mariya V Zhalnina, Stanislav D Zakharov, Onkar Sharma
and William A Cramer
The EMBO Journal (2008) 27, 15, 2171-2180
http://ealerts.nature.com/cgi-bin24/DM/y/emlp0Xztnp0Hh50B2Y30ED
Published online: 17 July 2008
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