ScienceDirect Alert: Cell, Vol. 133, Iss. 3, 2008

New Volume/Issue is now available on ScienceDirect

Cell Volume 133, Issue 3,  Pages 379-550 (2 May 2008)

Leading Edge

1.

In This Issue Pages 379, 381

2.

Molecular Medicine Select Pages 383, 385

Essay

3.

Xenohormesis: Sensing the Chemical Cues of Other Species Pages 387-391 Konrad T. Howitz and David A. Sinclair

Previews

4.

Death in the CNS: Six-Microns-Under Pages 393-395 Michael R. Elliott and Kodi S. Ravichandran

5.

Epigenome Sequencing Comes of Age Pages 395-397 Jian-Kang Zhu

6.

CaMKII: New Tricks for an Old Dog Pages 397-399 Leslie C. Griffith

7.

Substrate Selectivity APPLies to Akt Pages 399-400 Shimin Zhao and Kun-Liang Guan

8.

A Different TIPE of Immune Homeostasis Pages 401-402 Eric C. Freundt, Nicolas Bidere and Michael J. Lenardo

Review

9.

Tenets of PTEN Tumor Suppression Pages 403-414 Leonardo Salmena, Arkaitz Carracedo and Pier Paolo Pandolfi

Articles

10.

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis Pages 415-426 Honghong Sun, Shunyou Gong, Ruaidhri J. Carmody, Anja Hilliard, Li Li, Jing Sun, Li Kong, Lingyun Xu, Brendan Hilliard, Shimin Hu, Hao Shen, Xiaolu Yang and Youhai H. Chen

11.

Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex Pages 427-439 Claudio Ciferri, Sebastiano Pasqualato, Emanuela Screpanti, Gianluca Varetti, Stefano Santaguida, Gabriel Dos Reis, Alessio Maiolica, Jessica Polka, Jennifer G. De Luca, Peter De Wulf, Mogjiborahman Salek, Juri Rappsilber, Carolyn A. Moores, Edward D. Salmon and Andrea Musacchio

12.

SRP Keeps Polypeptides Translocation-Competent by Slowing Translation to Match Limiting ER-Targeting Sites Pages 440-451 Asvin K.K. Lakkaraju, Camille Mary, Anne Scherrer, Arthur E. Johnson and Katharina Strub

13.

Allosteric Regulation of Histidine Kinases by Their Cognate Response Regulator Determines Cell Fate Pages 452-461 Ralf Paul, Tina Jaeger, Sören Abel, Irene Wiederkehr, Marc Folcher, Emanuele G. Biondi, Michael T. Laub and Urs Jenal

14.

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation Pages 462-474 Jeffrey R. Erickson, Mei-ling A. Joiner, Xiaoqun Guan, William Kutschke, Jinying Yang, Carmine V. Oddis, Ryan K. Bartlett, John S. Lowe, Susan E. O'Donnell, Nukhet Aykin-Burns, Matthew C. Zimmerman, Kathy Zimmerman, Amy-Joan L. Ham, Robert M. Weiss, Douglas R. Spitz, Madeline A. Shea, Roger J. Colbran, Peter J. Mohler and Mark E. Anderson

15.

Pirt, a Phosphoinositide-Binding Protein, Functions as a Regulatory Subunit of TRPV1 Pages 475-485 Andrew Y. Kim, Zongxiang Tang, Qin Liu, Kush N. Patel, David Maag, Yixun Geng and Xinzhong Dong

16.

The Endosomal Protein Appl1 Mediates Akt Substrate Specificity and Cell Survival in Vertebrate Development Pages 486-497 Annette Schenck, Livia Goto-Silva, Claudio Collinet, Muriel Rhinn, Angelika Giner, Bianca Habermann, Michael Brand and Marino Zerial

17.

Six-Microns-Under Acts Upstream of Draper in the Glial Phagocytosis of Apoptotic Neurons Pages 498-509 Estee Kurant, Sofia Axelrod, Dan Leaman and Ulrike Gaul

18.

Identification of Positionally Distinct Astrocyte Subtypes whose Identities Are Specified by a Homeodomain Code Pages 510-522 Christian Hochstim, Benjamin Deneen, Agnès Lukaszewicz, Qiao Zhou and David J. Anderson

Resources

19.

Highly Integrated Single-Base Resolution Maps of the Epigenome in Arabidopsis Pages 523-536 Ryan Lister, Ronan C. O'Malley, Julian Tonti-Filippini, Brian D. Gregory, Charles C. Berry, A. Harvey Millar and Joseph R. Ecker

20.

Application of Active and Kinase-Deficient Kinome Collection for Identification of Kinases Regulating Hedgehog Signaling Pages 537-548 Markku Varjosalo, Mikael Björklund, Fang Cheng, Heidi Syvänen, Teemu Kivioja, Sami Kilpinen, Zairen Sun, Olli Kallioniemi, Hendrik G. Stunnenberg, Wei-Wu He, Päivi Ojala and Jussi Taipale

Errata

21.

MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks Page 549 Manuel Stucki, Julie A. Clapperton, Duaa Mohammad, Michael B. Yaffe, Stephen J. Smerdon and Stephen P. Jackson

SnapShot

22.

SnapShot: PTEN Signaling Pathways Pages 550-550.e1 Arkaitz Carracedo, Leonardo Salmena and Pier Paolo Pandolfi

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