6 March 2008 Volume 452 Number 7183, pp1-126
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----------------------
EDITORIALS
----------------------
No more scavenger hunts p1
The recent media flap over antidepressants highlights the need for
data to be transparent -- and for a mandatory database of all clinical
trials.
doi:10.1038/452001a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOg0EC
Time to connect pp1-2
More than ever, academics in Iran and in nations hostile to it should
communicate with each other.
doi:10.1038/452001b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOh0ED
The EPA's tailspin p2
The director of the Environmental Protection Agency is sabotaging both
himself and his agency.
doi:10.1038/452002a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOi0EE
----------------------
RESEARCH HIGHLIGHTS
----------------------
Research highlights p4-5
doi:10.1038/452004a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOj0EF
----------------------
JOURNAL CLUB
----------------------
Journal club p5
Keith Devlin
doi:10.1038/452005a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOk0EG
----------------------
NEWS
----------------------
Crunch time for peer review in lawsuit p6-7
Ruling imminent on Pfizer's challenge to journal confidentiality.
Meredith Wadman
doi:10.1038/452006a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOl0EH
Bright hopes pervade dark matter p6-7
Physicists unperturbed as Soudain mine detector draws a blank.
Geoff Brumfiel
doi:10.1038/452006b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOm0EI
Entomologists stifled by Indian bureaucracy p7
'Biopiracy' concerns thwart insect hunters.
K. S. Jayaraman
doi:10.1038/452007a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOn0EJ
Save the trees p8-9
Scientists and policy-makers will meet in Bonn this June to discuss
one of the most pressing concerns to come out of December's United
Nations climate meeting — how to manage the world's tropical forests.
Jeff Tollefson examines some of the proposals.
doi:10.1038/452008a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOo0EK
Magnets touted as fix for fusion reactor p11
ITER experiment faces up to effects of chaotic eruptions.
Eric Hand
doi:10.1038/452011a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOp0EL
Sidelines p12
Scribbles on the margins of science.
doi:10.1038/452012a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOq0EM
Hobbit was 'a cretin' p12
Fossil may be early example of hypothyroidism.
Rex Dalton
doi:10.1038/452012b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOr0EN
Nobel prizewinner's paper retracted p13
Failure to reproduce results deals blow to work on olfactory networks.
Heidi Ledford
doi:10.1038/452013a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOs0EO
UK scientists keep access to the Gemini telescopes p15
doi:10.1038/452015a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOt0EP
Massachusetts gears up to boost cash for life sciences p15
doi:10.1038/452015b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOu0EQ
First of three contested stem-cell patents upheld p15
doi:10.1038/452015c
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOv0ER
India to propose regulatory body to curb misconduct p15
doi:10.1038/452015d
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOw0ES
US$50 billion agreed for Bush's global AIDS plan p15
doi:10.1038/452015e
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOx0ET
Lunar pole is revealed in high resolution p15
doi:10.1038/452015f
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOy0EU
----------------------
CORRECTION
----------------------
Correction p15
doi:10.1038/452015g
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpOz0EV
----------------------
COLUMN
----------------------
The scientist delusion p17
Religious resistance to science is often exaggerated, but fresh
problems may lie ahead, says David Goldston.
doi:10.1038/452017a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO10EI
----------------------
NEWS FEATURES
----------------------
Astronomy: Hearing the heavens p18-21
The cosmos is thought to be awash with gravitational waves to which
humanity is, as yet, deaf.
Trudy E. Bell reports on LISA, an experiment on an unprecedented scale
designed to put that right.
doi:10.1038/452018a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO20EJ
Archaeology: Facing up to the past p22-23
New York University is trying to establish a world-class
archaeological institute - with funds from a philanthropist who has
been linked to looted artefacts.
Rex Dalton reports.
doi:10.1038/452022a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO30EK
Oceanography: Red tide rising p24-26
Algal blooms can make life miserable for coastal dwellers and wreak
havoc on marine ecosystems.
Mark Schrope reports on Florida's efforts to predict these red tides.
doi:10.1038/452024a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO40EL
----------------------
CORRESPONDENCE
----------------------
Who stands to lose from double-blind review? p28
Boyan K. Garvalov
doi:10.1038/452028a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO50EM
Double-blind review: the paw print is a giveaway p28
K. Razi Naqvi
doi:10.1038/452028b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO60EN
Double-blind review: easy to guess in specialist fields p28
David Lane
doi:10.1038/452028c
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO70EO
Double-blind review: let diversity reign p28
Bob O'Hara
doi:10.1038/452028d
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpO80EP
Tibet's seeds must be stored as climate changes p28
W. John Cram, Yang Zhong, Tashi Tersing and Jie Cai
doi:10.1038/452028e
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPA0EZ
Duplication: stop favouring applicant with longest list p29
Martin Fenner
doi:10.1038/452029a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPB0Ea
Duplication spreads the word to a wider audience p29
Daniel David
doi:10.1038/452029b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPC0Eb
Duplication and plagiarism increasing among students p29
Brian Derby
doi:10.1038/452029c
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPD0Ec
Duplication: most cases on database are innocent p29
Paul Brennan
doi:10.1038/452029d
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPE0Ed
----------------------
BOOKS AND ARTS
----------------------
Physics to Bragg about p30
The first joint biography of the father and son who developed X-ray
crystallography.
Jeff Hughes reviews William and Lawrence Bragg, Father and Son: The
Most Extraordinary Collaboration in Science by John Jenkin
doi:10.1038/452030a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPF0Ee
Climate change for the masses p31
David S. Reay reviews The Hot Topic by Gabrielle Walker and David King
doi:10.1038/452031a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPG0Ef
Hacking: Crafters tinker with technology p32
Krista Zala
doi:10.1038/452032a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPH0Eg
Hacking: Home cooking with a twist p32-33
Jascha Hoffman
doi:10.1038/452032b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPI0Eh
Hacking: Toys, bugs and rock 'n' roll p33
Joanne Baker reviews Stranger On A Train
doi:10.1038/452033a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPJ0Ei
In Retrospect: The book that began invasion ecology p34
Charles Elton's 50-year-old text founded a field and is now cited more
than ever.
Anthony Ricciardi and Hugh J. MacIsaac reviews The Ecology of
Invasions by Animals and Plants by Charles S. Elton
doi:10.1038/452034a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPK0Ej
----------------------
NEWS AND VIEWS
----------------------
Physiology: Keeping it regular with protons p35-36
Muscle coordination is mostly governed by motor programs built into
the nervous system. But one program -- the defecation cycle in a
worm -- has a mechanism that avoids nerves completely and uses protons
as signals.
Laura M. Prolo and Miriam B. Goodman
doi:10.1038/452035a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPL0Ek
Quantum physics: Tangled memories p37-38
The latest quantum trick -- mapping two entangled photon states onto
two separate regions of an atomic cloud, and then retrieving them --
could be a fillip for applications, among them quantum cryptography.
Lene Vestergaard Hau
doi:10.1038/452037a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPM0El
50 & 100 Years Ago p37
doi:10.1038/452037b
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPN0Em
Neuroscience: A complex in psychosis p38-39
The molecular basis of psychoses such as schizophrenia remains largely
mysterious. The interaction between two of the brain receptors
involved adds to evidence that will help in the search for
explanations.
Solomon H. Snyder
doi:10.1038/452038a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPO0En
Ageing: Rushed decisions p39
Sadaf Shadan
doi:10.1038/452039a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPP0Eo
Palaeontology: Modern life in ancient mats p40-41
Microbial communities seem to have inhabited tidal sediments 2.9
billion years ago much as they do today -- but what organisms were
involved, and how they made their living, remain intriguing questions.
Michael M. Tice
doi:10.1038/452040a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPQ0Ep
Magnetospheric physics: Hiss from the chorus p41-42
What is the origin of the broadband, low-intensity radio waves thought
to control the radiation belts that surround Earth? The latest
suggestion sees this 'hiss' emerging from an unsuspected quarter.
Craig J. Rodger and Mark A. Clilverd
doi:10.1038/452041a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPR0Eq
Genomics: Fungal symbiosis unearthed p42-43
Associations between plant roots and fungi are a feature of many
terrestrial ecosystems. The genome sequence of a prominent fungal
partner opens new avenues for studying such mycorrhizal interactions.
Dan Cullen
doi:10.1038/452042a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPS0Er
Solid-state physics: How does your quasicrystal grow? p43-44
Somewhere between the amorphous glasses and the rigidly regimented
periodic crystals lie the quasicrystals: ordered, predictable, yet
non-periodic arrangements of atoms. How do these strange structures
form?
Paul J. Steinhardt
doi:10.1038/452043a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPT0Es
----------------------
BRIEF COMMUNICATIONS ARISING
----------------------
Arousal by stimulation of deep-brain nuclei pE1
Hugh Staunton
doi:10.1038/nature06574
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPU0Et
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPV0Eu
Schiff et al. reply pE1-E2
N. D. Schiff et al.
doi:10.1038/nature06575
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPW0Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPX0Ew
----------------------
ARTICLES
----------------------
Cyclical DNA methylation of a transcriptionally active promoter p45-50
Cycles of DNA methylation and demethylation are observed at the pS2
gene promoter during its activation by oestrogen, accompanied by
cycling of DNA methyltransferases and other factors; this contrasts
with the accepted view of DNA methylation as a stable epigenetic mark.
Raphael Metivier et al.
doi:10.1038/nature06544
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPY0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPZ0Ey
The MC-Fold and MC-Sym pipeline infers RNA structure from sequence
data p51-55
A series of algorithms representing a significant technical advance in
determining RNA structure from sequence alone is presented; the
algorithms take into account all base pairing interactions to yield
three dimensional structure.
Marc Parisien and Francois Major
doi:10.1038/nature06684
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPa0E6
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPb0E7
Structure and metal exchange in the cadmium carbonic anhydrase of
marine diatoms p56-61
The X ray crystal structures of the cadmium bound, zinc bound, metal
free and acetate bound forms of cadmium carbonic anhydrase are solved;
the enzyme can incorporate either zinc or cadmium as its metal centre
and can easily exchange one metal for the other.
Yan Xu et al.
doi:10.1038/nature06636
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPc0E8
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPd0EA
----------------------
LETTERS
----------------------
The unexpected origin of plasmaspheric hiss from discrete chorus
emissions p62-66
An electromagnetic wave called chorus, previously thought to be
unrelated to plasmaspheric hiss, has been shown to propagate into the
plasmasphere and subsequently evolve into hiss.
Jacob Bortnik, Richard M. Thorne and Nigel P. Meredith
doi:10.1038/nature06741
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPe0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPf0EC
Mapping photonic entanglement into and out of a quantum memory p67-71
A protocol where entanglement between two atomic ensembles is created
by coherent mapping of an entangled state of light, effectively
separating the generation of entanglement and its storage, is
reported.
K. S. Choi, H. Deng, J. Laurat and H. J. Kimble
doi:10.1038/nature06670
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPg0ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPh0EE
Strong dispersive coupling of a high-finesse cavity to a
micromechanical membrane p72-75
A report on an improved design of an optomechanical system in which
a movable membrane is placed between two rigid high quality mirrors,
as opposed to previous designs where one of the mirrors has a double
function as the microresonator; it's claimed that it is feasible to
reach the quantum-limited ground state with this new design.
J. D. Thompson et al.
doi:10.1038/nature06715
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPi0EF
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPj0EG
Multi-membrane hydrogels p76-79
A multi step interrupted gelation process to generate complex
hydrogels with multi membrane 'onion like' and tubular architectures
has been developed. The method allows the formation of free
'inter membrane' spaces well suited for an easy cell or drug
introduction.
Sebastien Ladet, Laurent David and Alain Domard
doi:10.1038/nature06619
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPk0EH
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPl0EI
Near-isothermal conditions in the middle and lower crust induced by
melt migration p80-83
Simple one-dimensional thermal models that include the effects of melt
migration have been developed. The models show that long lived
plutonism results in a quasi steady state geotherm with a rapid
temperature increase in the upper crust and nearly isothermal
conditions in the middle and lower crust.
Gabriela V. Depine, Christopher L. Andronicos and Jason Phipps-Morgan
doi:10.1038/nature06689
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPm0EJ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPn0EK
High-amplitude fluctuations and alternative dynamical states of midges
in Lake Myvatn p84-87
An example of complex population dynamics (the midge Tanytarsus
gracilentus in Lake Myvatn, Iceland) is described and modelled.
Anthony R. Ives, Arni Einarsson, Vincent A. A. Jansen and Arnthor Gardarsson
doi:10.1038/nature06610
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPo0EL
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPp0EM
The genome of Laccaria bicolor provides insights into mycorrhizal
symbiosis p88-92
F. Martin et al.
The genome of the fungus Laccaria bicolor is described; it is of keen
interest to evolutionary and plant biologists for its revelations
about plant–fungus interactions shaping genomes over time.
doi:10.1038/nature06556
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPq0EN
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPr0EO
Identification of a serotonin/glutamate receptor complex implicated
in psychosis p93
Metabotropic glutamate receptors (downregulated in untreated
schizophrenics) interact with the serotonin 2A receptor to form a
functional complex in the brain; this complex triggers unique
responses when activated by hallucinogenic drugs, and may represent a
new target for the treatment of psychosis.
Javier González-Maeso et al.
doi:10.1038/nature06612
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPs0EP
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPt0EQ
Hax1-mediated processing of HtrA2 by Parl allows survival of
lymphocytes and neurons p98
Insights into the function of Hax1 are provided by a study showing that
Hax1 facilitates the processing of the mitochondrial protease HtrA2 by
the mitochondrial rhomboid protease Parl. It is the protease activity
of HtrA2 that is essential to suppress apoptosis in both lymphocytes
and striatal neurons.
Jyh-Rong Chao, Evan Parganas, Kelli Boyd, Cheol Yi Hong,
Joseph T. Opferman & James N. Ihle
doi:10.1038/nature06604
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPu0ER
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPv0ES
The inflammasome recognizes cytosolic microbial and host DNA and
triggers an innate immune response p103
Activation of inflammasomes leads to maturation of the pro
inflammatory cytokine IL 1beta; this study adds DNA to the growing
list of exogenous and endogenous inflammasome activators.
Daniel A. Muruve et al.
doi:10.1038/nature06664
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPw0ET
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPx0EU
A peptide deformylase–ribosome complex reveals mechanism of nascent
chain processing p108
This study determines how peptide deformylase interacts with the
ribosome and how protein synthesis is coupled to processing of newly
made proteins.
Rouven Bingel-Erlenmeyer et al.
doi:10.1038/nature06683
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPy0EV
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpPz0EW
Transient cyclical methylation of promoter DNA p112-115
One of two papers this issue reporting cycles of DNA methylation and
demethylation of CpG dinucleotides at gene promoters. Here, cyclical
DNA methylation is reported at five active promoters; this contrasts
with the accepted view of DNA methylation as a stable epigenetic mark.
Sara Kangaspeska et al.
doi:10.1038/nature06640
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP10EJ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP20EK
Structure of the DNA deaminase domain of the HIV-1 restriction factor
APOBEC3G p116
The cellular cytosine deaminase APOBEC3G inhibits replication of HIV
lacking the viral protein Vif; here the NMR structure of a mutant form
of the catalytic domain of APOBEC3G is reported, and a model for the
APOBEC–DNA interaction is proposed.
Kuan-Ming Chen et al.
doi:10.1038/nature06638
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP30EL
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP40EM
----------------------
CORRIGENDUM
----------------------
Behavioural improvements with thalamic stimulation after severe
traumatic brain injury p120
N. D. Schiff et al.
doi:10.1038/nature06818
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP50EN
----------------------
RETRACTION
----------------------
Genetic tracing reveals a stereotyped sensory map in the olfactory
cortex p120
Zhihua Zou et al.
doi:10.1038/nature06819
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP60EO
----------------------
NATURE JOBS
----------------------
Prospect
Prospects p121
Are animal-rights attacks affecting career paths?
Gene Russo
doi:10.1038/nj7183-121a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP70EP
Region
Almost in bloom p122
St Louis wants to become a hub of agricultural biotechnology. All it
needs, says Emma Marris, is more start-ups and funds.
doi:10.1038/nj7183-122a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpP80EQ
----------------------
FUTURES
----------------------
From Alice to everywhere, with love p126
A leap into the unknown.
Chaz Brenchley
doi:10.1038/452126a
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQA0Ea
------------------------------
ADVANCE ONLINE PUBLICATION
------------------------------
05 March 2008
Article
Isolation of an active step I spliceosome and composition of its RNP core
Sergey Bessonov, Maria Anokhina, Cindy L. Will, Henning Urlaub
& Reinhard Lührmann
doi:10.1038/nature06842
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQB0Eb
Letters
Broad phylogenomic sampling improves resolution of the animal tree
of life
Casey W. Dunn et al.
doi:10.1038/nature06614
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQC0Ec
Memory CD4 T cells emerge from effector T-cell progenitors
Laurie E. Harrington, Karen M. Janowski, James R. Oliver,
Allan J. Zajac & Casey T. Weaver
doi:10.1038/nature06672
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQD0Ed
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
Ricarda J. C. Hilf & Raimund Dutzler
doi:10.1038/nature06717
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQE0Ee
Identifying natural images from human brain activity
Kendrick N. Kay, Thomas Naselaris, Ryan J. Prenger & Jack L. Gallant
doi:10.1038/nature06713
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQF0Ef
02 March 2008
Letters
Biodiversity and biogeography of phages in modern stromatolites
and thrombolites
Christelle Desnues et al.
doi:10.1038/nature06735
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQG0Eg
Localization and functionality of microsporidian iron–sulphur cluster
assembly proteins
Alina V. Goldberg et al.
doi:10.1038/nature06606
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQH0Eh
A skin microRNA promotes differentiation by repressing 'stemness'
Rui Yi, Matthew N. Poy, Markus Stoffel & Elaine Fuchs
doi:10.1038/nature06642
http://ealerts.nature.com/cgi-bin24/DM/y/ejYJ0Xztnp0HjB0BpQI0Ei
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