ScienceDirect Alert: Cell, Vol. 132, Iss. 1, 2008

New Volume/Issue is now available on ScienceDirect

Cell Volume 132, Issue 1,  Pages 1-162 (11 January 2008)

Leading Edge

1.

In This Issue Pages 1, 3

2.

Molecular Medicine Select Pages 5, 7

Essay

3.

Getting to the Root of miRNA-Mediated Gene Silencing Pages 9-14 Ana Eulalio, Eric Huntzinger and Elisa Izaurralde

Correspondence

4.

Re-examining the Stability of the Bicoid Morphogen Gradient Pages 15-17 Sven Bergmann, Zvi Tamari, Eyal Schejter, Ben-Zion Shilo and Naama Barkai

5.

Response: Can We Fit All of the Data Pages 17-18 William Bialek, Thomas Gregor, David W. Tank and Eric F. Wieschaus

Previews

6.

XMAP215: A Tip Tracker that Really Moves Pages 19-20 Charles L. Asbury

7.

Protons as Intercellular Messengers Pages 21-22 Joanne S.M. Kim and Mei Zhen

8.

PTRF Triggers a Cave In Pages 23-24 Rahul Chadda and Satyajit Mayor

9.

How IRE1 Reacts to ER Stress Pages 24-26 David Ron and Stevan R. Hubbard

Review

10.

Autophagy in the Pathogenesis of Disease Pages 27-42 Beth Levine and Guido Kroemer

Articles

11.

Structure of a Sliding Clamp on DNA Pages 43-54 Roxana E. Georgescu, Seung-Sup Kim, Olga Yurieva, John Kuriyan, Xiang-Peng Kong and Mike O'Donnell

12.

Global Twisting Motion of Single Molecular KcsA Potassium Channel upon Gating Pages 67-78 Hirofumi Shimizu, Masayuki Iwamoto, Takashi Konno, Amiko Nihei, Yuji C. Sasaki and Shigetoshi Oiki

13.

XMAP215 Is a Processive Microtubule Polymerase Pages 79-88 Gary J. Brouhard, Jeffrey H. Stear, Tim L. Noetzel, Jawdat Al-Bassam, Kazuhisa Kinoshita, Stephen C. Harrison, Jonathon Howard and Anthony A. Hyman

14.

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing Pages 89-100 Kenneth P.K. Lee, Madhusudan Dey, Dante Neculai, Chune Cao, Thomas E. Dever and Frank Sicheri

15.

Dissecting the ER-Associated Degradation of a Misfolded Polytopic Membrane Protein Pages 101-112 Kunio Nakatsukasa, Gregory Huyer, Susan Michaelis and Jeffrey L. Brodsky

16.

PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function Pages 113-124 Michelle M. Hill, Michele Bastiani, Robert Luetterforst, Matthew Kirkham, Annika Kirkham, Susan J. Nixon, Piers Walser, Daniel Abankwa, Viola M.J. Oorschot, Sally Martin, John F. Hancock and Robert G. Parton

17.

A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior Pages 125-136 Jean-Martin Beaulieu, Sébastien Marion, Ramona M. Rodriguiz, Ivan O. Medvedev, Tatyana D. Sotnikova, Valentina Ghisi, William C. Wetsel, Robert J. Lefkowitz, Raul R. Gainetdinov and Marc G. Caron

18.

Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation Pages 137-148 Jian-Sheng Kang, Jin-Hua Tian, Ping-Yue Pan, Philip Zald, Cuiling Li, Chuxia Deng and Zu-Hang Sheng

19.

Protons Act as a Transmitter for Muscle Contraction in C. elegans Pages 149-160 Asim A. Beg, Glen G. Ernstrom, Paola Nix, M. Wayne Davis and Erik M. Jorgensen

SnapShot

20.

SnapShot: Macroautophagy Pages 162.e1-162.e3 Beth Levine and Guido Kroemer

21.

MazF, an mRNA Interferase, Mediates Programmed Cell Death during Multicellular Myxococcus Development Pages 55-66 Hirofumi Nariya and Masayori Inouye

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