13 December 2007 Volume 450 Number 7172, pp 921 - 1126
Visit Nature online to browse the journal.
Now available at http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0d4W0EE
Please note that you need to be a subscriber to enjoy full text
access to Nature online. To purchase a subscription, please visit:
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0Z4L0Er
Alternatively, to recommend a subscription to your library,
please visit
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BRQi0En
======================================================================
Finnzymes' High Performance PCR
===============================
Our integrated solution provides high-fidelity PCR with 2 to 4-fold
greater yields in under half the time as compared with conventional PCR.
Come see why Finnzymes' reagents, instruments and vessels provide a
winning combination every time.
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjK50EF
======================================================================
Nature Reviews Molecular Cell Biology
Poster - Readout of chromatin marks by histone-binding modules
The poster illustrates well-known histone marks and the 3D structures
of representative histone-binding modules, and outlines emerging theme
s in the molecular recognition of modified histones.
Visit www.nature.com/nrm/posters/histonemarks for free online access.
Produced with support from:
abcam
======================================================================
Nature Insights Proteins to proteomes
Biochemists began by taking cells apart, and have worked hard to
isolate cellular components from each other in order to understand
elementary functions. After close to two centuries of intense labour,
and now that full part lists (genomes) have been completed, they are
faced with the problem of understanding how all those parts work
together as a coherent ensemble. This Insight highlights some of the
most exciting new discoveries involving the protein world.
Read the Insight in this issue of Nature or access the Insight free
online at: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB04uA0E8
Produced with support from Pfizer
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0Bed60Ea
======================================================================
----------------------
EDITORIALS
----------------------
Directive action required p921
Europe's handling of applications to grow genetically modified crops
amounts to bad governance.
doi:10.1038/450921a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLs0EI
Hollow victory pp921 - 922
More benign global AIDS statistics do not mean that the battle against
HIV is being won.
doi:10.1038/450921b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLt0EJ
Venezuela's way ahead p922
The opportunities currently opening up for Venezuelan science should
not be squandered.
doi:10.1038/450922a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLu0EK
----------------------
RESEARCH HIGHLIGHTS
----------------------
Research highlights pp924 - 925
doi:10.1038/450924a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLv0EL
----------------------
JOURNAL CLUB
----------------------
Journal club p925
Paul Mulvaney
doi:10.1038/450925a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLw0EM
----------------------
NEWS
----------------------
London to host ambitious research hub pp926 - 927
UK Medical Research Council heads for King's Cross.
Andrea Chipman
doi:10.1038/450926a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLx0EN
Nuclear-reactor closure hits cancer tests pp926 - 927
Shortage of radioisotopes reaches US patients.
Hannah Hoag
doi:10.1038/450926b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLy0EO
Enigmatic clouds illuminated p927
Satellite data shed light on twilight skies.
Alexandra Witze
doi:10.1038/450927a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjLz0EP
Showdown for Europe pp928 - 929
The European Union is set to make a landmark decision on genetically
modified crops, as Alison Abbott and Quirin Schiermeier report.
doi:10.1038/450928a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL10EC
Sidelines pp929 - 929
Scribbles on the margins of science.
doi:10.1038/450929a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL20ED
Moonlighting missions pp931 - 931
Where next for NASA?
doi:10.1038/450931a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL30EE
=====================================================================
PREFERRED BY OVER 200,000 RESEARCHERS!
======================================
SigmaPlot 10 produces publication-quality graphs and solves simple and
advanced curve fitting problems.
Get a FREE and FULLY FUNCTIONAL 30-day trial of SigmaPlot at:
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL40EF
E-mail us and mention this mail to get FREE SHIPPING on new or upgrade
purchases.
=====================================================================
Poor nations claim victory at climate talks pp932 - 932
doi:10.1038/450932a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL50EG
'Heated bidding' for rocket scientist's thesis pp932 - 932
doi:10.1038/450932b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL60EH
Switzerland launches systems-biology initiative pp932 - 933
doi:10.1038/450932c
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL70EI
US politicians push for food-safety funding boost pp933 - 933
doi:10.1038/450933a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjL80EJ
Private funds raise hopes for giant telescope pp933 - 933
doi:10.1038/450933b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMA0ET
Hackers steal personal data from US laboratories pp933 - 933
doi:10.1038/450933c
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMB0EU
----------------------
CORRECTION
----------------------
Correction pp933 - 933
doi:10.1038/450933d
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMC0EV
----------------------
BUSINESS
----------------------
Promise boiling over p934
Geothermal power is one of the hottest prospects in the burgeoning
clean-energy market. But, as Kurt Kleiner reports, it's not close
enough to home for many uses.
Kurt Kleiner
doi:10.1038/450934a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjPn0EH
Euro tie-up pp935 - 935
doi:10.1038/450935a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMD0EW
Mutual mouse pp935 - 935
doi:10.1038/450935b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjME0EX
No approval pp935 - 935
doi:10.1038/450935c
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMF0EY
Market watch pp935 - 935
Colin Macilwain
doi:10.1038/450935d
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMG0EZ
----------------------
NEWS FEATURES
----------------------
Gardening: A garden for all climates pp937 - 939
Accustomed to adapting to nature's whims, gardeners are more prepared
than most to take on the challenge of climate change.
Emma Marris asks them what to grow in a greenhouse world.
doi:10.1038/450937a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMH0Ea
Archaeology: Pieces of the puzzle pp940 - 941
After decades of war, looting and destruction, Afghanistan's
archaeologists are scrambling to restore their country's cultural
heritage. Rex Dalton visited Kabul to see how they are faring.
doi:10.1038/450940a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMI0Eb
Abnormal neuroscience: Scanning psychopaths pp942 - 944
Are their brains not wired to feel what others feel, or do they just
not care? Alison Abbott joins researchers looking into normal
neurobiology through the scope of psychopathy.
doi:10.1038/450942a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMJ0Ec
----------------------
CORRESPONDENCE
----------------------
All fishing nations must unite to cut subsidies p945
U. Rashid Sumaila and Daniel Pauly
doi:10.1038/450945a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMK0Ed
Debate over flood-proofing effects of planting forests p945
Ian R. Calder, James Smyle and Bruce Aylward
doi:10.1038/450945b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjML0Ee
Motivation needed to cure lifestyle diseases p945
Werner Waldhausl
doi:10.1038/450945c
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMM0Ef
Educational success must start in Pakistan's schools p945
Masroor Bangesh
doi:10.1038/450945d
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMN0Eg
----------------------
BOOKS AND ARTS
----------------------
Children's Books: Small matters, big issues pp946 - 947
Science books for children are thriving, partly because of the
competition from new media.
Harriet Coles reviews Why is Snot Green? by Glenn Murphy, The Gooey
Chewy Rumble Plop Book by Steve Alton and Nick Sharratt, Horrible
Science Annual 2008 by Nick Arnold, Famously Foul Experiments by
Nick Arnold, What's Eating You? by Nicola Davies and Neal Layton,
The Global Garden by Kate Petty and Jennie Maizels and Germ Stories by
Authur Kornberg and Adam Alanz
doi:10.1038/450946a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMO0Eh
Children's books: Young planet-savers pp947 - 948
Tom Standage and Ella (7 1/2) reviews Is That a Butterfly by
Claire Llewellyn and Ant Parker, George Saves the World by Lunchtime
by Jo and Ley Honor Roberts, Spud Goes Green by Giles 101 Ways to Save
the Earth by David Bellamy and Penny Dann, Superkids: 250 Incredible
Ways for Kids to Save the Planet by Sasha Norris and An Inconvenient
Truth: The Crisis of Global Warming by Al Gore
doi:10.1038/450947a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMP0Ei
Children's Books: Hawking's fact and fiction p949
George F. R. Ellis and Ruby (10) reviews George's Secret Key to the
Universe by Lucy and Stephen Hawking
doi:10.1038/450949a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMQ0Ej
Children's Books: Stones, bones and stories pp949 - 950
Henry Gee, Phoebe (9) and Rachel (7) reviews Life Story by
Eric Maddern and Leo Duff, The Story of Everything by Neal Layton,
The Pebble In My Pocket by Meredith Hooper and Chris Coady, Ask Dr K
Fisher about Dinosaurs by Claire Llewellyn and Kate Sheppard,
Prehistoric Actual Size by Steve Jenkins, The Fossil Girl by
Catherine Brighton, Stone Girl Bone Girl by Laurence Anholt and
Sheila Moxley and The Human Story by Charles Lockwood
doi:10.1038/450949b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMR0Ek
Children's Books: Star tales p950
Mark Brake reviews Earth Story by Eric Maddern and Leo Duff,
Stardust from Space by Monica Grady and Lucia deLeiris,
Zoo in the Sky by Jacqueline Mitton and Christina Balit,
Kingdom of the Sun by Jacqueline Mitton and Christina Balit,
Galileo: Scientist and Star Gazer by Jacqueline Mitton and Gerry Ball
and Moon Man by David Donohue
doi:10.1038/450950a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMS0El
Children's books: To bodily go ... p951
Ian Jones reviews Inside You: How Your Body Makes it Through Every Day
by Mark Hamilton
doi:10.1038/450951a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMT0Em
Children's books: Mathematics not shopping pp951 - 952
Joanna Sabatino-Hernandez reviews Math Doesn't Suck by Danica McKellar
doi:10.1038/450951b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMU0En
Children's Books: The scene is set p952
Glenn Murphy reviews Wow! Inventions That Changed the World by
Phillip Ardagh, Natural History Museum Animal Records by Mark Carwardine,
Actual Size by Steve Jenkins and How To Be A Brain Surgeon by Amanda Li
doi:10.1038/450952a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMV0Eo
----------------------
NEWS AND VIEWS
----------------------
Photonics: Rogue waves surface in light pp953 - 954
How do the freak waves that haunt seafarers' nightmares arise? We
don't know, is the short answer -- but the discovery of a similar
phenomenon in optical waves might assist in getting to the bottom of
the mystery.
Dong-Il Yeom and Benjamin J. Eggleton
doi:10.1038/450953a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMW0Ep
50 & 100 Years Ago p954
doi:10.1038/450954a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMX0Eq
Malaria: Differential parasite drive pp955 - 956
Our knowledge of the inner workings of malaria parasites comes largely
from lab-based studies. But parasites growing in humans may have
greater metabolic flexibility than those growing in Petri dishes.
Giel G. van Dooren and Geoffrey I. McFadden
doi:10.1038/450955a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMY0Er
Astronomy: Dim view of past clashes pp956 - 957
Simulations indicate that faint galaxies of a seemingly tranquil
class were born in violent cosmic encounters. This would be good news
for the prevailing model of how the Universe is constructed.
Curtis Struck
doi:10.1038/450956a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMZ0Es
Structural biology: Ion pumps made crystal clear pp957 - 959
The function of every cell in our bodies depends on the work of
proteins known as ion pumps. Several new crystal structures cast
fresh light on how three different pumps deal with their distinct
cargoes of ions.
David C. Gadsby
doi:10.1038/450957a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMa0Ez
Molecular biology: Genome under surveillance pp959 - 960
Decoding the information stored in DNA requires an intricate balance
between processes that turn gene expression on or off. A protein that
influences the packaging of DNA regulates this balance genome-wide.
Karen M. Arndt
doi:10.1038/450959a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMb0E1
Materials chemistry: Cool conditions for mobile ions pp960 - 961
A complex iron oxide has been made that has an unusual crystal
structure suggesting that the oxide ions are surprisingly mobile. This
finding could pave the way to other metal-oxide materials with useful
properties.
Michael A. Hayward and Matthew J. Rosseinsky
doi:10.1038/450960a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMc0E2
Correction p961
doi:10.1038/450961a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMd0E3
Obituary: Gene H. Golub (1932-2007) p962
Mathematician and godfather of numerical analysis.
Lloyd N. Trefethen
doi:10.1038/450962a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMe0E4
----------------------
INSIGHT
----------------------
INTRODUCTION
Proteins to proteomes p963
Tanguy Chouard and Joshua Finkelstein
doi:10.1038/450963a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMf0E5
REVIEW ARTICLE
Dynamic personalities of proteins pp964 - 972
Katherine Henzler-Wildman and Dorothee Kern
doi:10.1038/nature06522
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMg0E6
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMh0E7
The molecular sociology of the cell pp973 - 982
Carol V. Robinson, Andrej Sali and Wolfgang Baumeister
doi:10.1038/nature06523
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMi0E8
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMj0EA
The origin of protein interactions and allostery in colocalization pp983 - 990
John Kuriyan and David Eisenberg
doi:10.1038/nature06524
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMk0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMl0EC
The biological impact of mass-spectrometry-based proteomics pp991 - 1000
Benjamin F. Cravatt, Gabriel M. Simon and John R. Yates III
doi:10.1038/nature06525
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMm0ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMn0EE
Reaching for high-hanging fruit in drug discovery at protein-protein
interfaces pp1001 - 1009
James A. Wells and Christopher L. McClendon
doi:10.1038/nature06526
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMo0EF
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMp0EG
----------------------
REVIEW
----------------------
Transformation and diversification in early mammal evolution pp1011 - 1019
A host of recently discovered fossils shows that mammal evolution was
less a linear tale than a complex bush, in which mammalian feature
evolved repeatedly in separate lineages, and were sometimes lost.
Zhe-Xi Luo
doi:10.1038/nature06277
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMq0EH
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMr0EI
----------------------
BRIEF COMMUNICATIONS ARISING
----------------------
Kimberlite ascent and eruption pE21
R. S. J. Sparks, R. J. Brown, M. Field and M. Gilbertson
doi:10.1038/nature06435
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMs0EJ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMt0EK
Wilson & Head reply pE22
Lionel Wilson and James W. Head III
doi:10.1038/nature06436
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMu0EL
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMv0EM
----------------------
ARTICLES
----------------------
Two stellar components in the halo of the Milky Way pp1020 - 1025
The halo of the Milky Way is clearly divisible into two broadly
overlapping structural components, an inner and an outer halo. While
the inner halo has a modest net prograde rotation, the outer halo
exhibits a net retrograde rotation and a peak metallicity one third
that of the inner.
Daniela Carollo et al.
doi:10.1038/nature06460
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMw0EN
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMx0EO
Molecular code for transmembrane-helix recognition by the Sec61 translocon pp1026 - 1030
How the Sec translocon recognises transmembrane alpha-helices in newly
synthesised proteins is revealed by the analysis of a large number of
hydrophobic segments and presentation of a quantitative analysis of
the position-dependent contribution of efficiency of membrane
insertion for all amino acids. The results support the idea that
recognition of transmembrane helices by the Sec translocon is a
lipid-partitioning process.
Tara Hessa et al.
doi:10.1038/nature06387
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMy0EP
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjMz0EQ
Chromatin remodelling at promoters suppresses antisense transcription pp1031 - 1035
The yeast chromatin remodelling complex Isw2 repositions nucleosomes
that are adjacent to promoter regions and enforces directionality on
transcription by preventing inappropriate transcription initiation
from cryptic sites.
Iestyn Whitehouse, Oliver J. Rando, Jeff Delrow and Toshio Tsukiyama
doi:10.1038/nature06391
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM10ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM20EE
The structural basis of calcium transport by the calcium pump pp1036 - 1042
In plants and fungi, cellular ion homeostasis is powered by the proton
pump, a member of the P-type ATPase family. The first X-ray structure
of the H+-ATPase is presented, and insight into the mechanism by which
protons are transported against an electrochemical gradient is provided
Claus Olesen et al.
doi:10.1038/nature06418
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM30EF
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM40EG
Crystal structure of the sodium-potassium pump pp1043 - 1049
Relatively little is known about the mechanisms that underlie the
active transport of ions by Na+,K+-ATPase. A 3.5 A X-ray structure
of this fundamental protein is presented, revealing the two binding
sites for potassium.
J. Preben Morth et al.
doi:10.1038/nature06419
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM50EH
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM60EI
----------------------
LETTERS
----------------------
A dynamic, rotating ring current around Saturn pp1050 - 1053
S. M. Krimigis et al.
doi:10.1038/nature06425
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM70EJ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjM80EK
Optical rogue waves pp1054 - 1057
The concept of rogue waves in an optical system is investigated by
utilizing a new real-time detection technique to study a system that
exposes extremely steep, large optical waves as rare outcomes from
injection of a population of almost-identical optical pulses. Analysis
of these results finds that the optical rogue waves arise when random
noise perturbs the initially smooth pulses with a certain frequency
shift and within a well-defined time window.
D. R. Solli, C. Ropers, P. Koonath and B. Jalali
doi:10.1038/nature06402
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNA0EU
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNB0EV
A distinct bosonic mode in an electron-doped high-transition-temperature
superconductor pp1058 - 1061
A bosonic excitation (mode) at energies 10.5 +- 2.5 meV in the
electron doped superconductor Pr0.88LaCe0.12CuO4 (PLCCO) is reported.
The analysis of this indicates an electronic origin of the mode
consistent with spin excitations rather than phonons.
F. C. Niestemski et al.
doi:10.1038/nature06430
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNC0EW
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjND0EX
Infinite-layer iron oxide with a square-planar coordination pp1062 - 1065
The synthesis of SrFeO2, a new compound bearing a square-planar oxygen
coordination around Fe2+, is shown. SrFeO2 is isostructural with
'infinite layer' cupric oxides, and exhibits a magnetic order far
above room temperature.
Y. Tsujimoto et al.
doi:10.1038/nature06382
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNE0EY
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNF0EZ
Effect of remote sea surface temperature change on tropical cyclone
potential intensity pp1066 - 1070
The relationship between changes in sea surface temperature and a
measure called 'tropical cyclone potential intensity', which provides
an upper bound on cyclone intensity, is explored. It is found that
changes in potential intensity are closely related to the regional
structure of warming, rather than local sea surface temperature --
regions that warm more than the tropical average are characterized by
increased potential intensity, and vice versa.
Gabriel A. Vecchi and Brian J. Soden
doi:10.1038/nature06423
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNG0Ea
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNH0Eb
Dynamics of Mid-Palaeocene North Atlantic rifting linked with European
intra-plate deformations pp1071 - 1074
Soren B. Nielsen, Randell Stephenson and Erik Thomsen
doi:10.1038/nature06379
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNI0Ec
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNJ0Ed
Fetal load and the evolution of lumbar lordosis in bipedal hominins pp1075 - 1078
Pregnancy makes the instability of upright walking even worse by its
constant shifting the centre of gravity. The anatomical adaptations
peculiar to female spines that balance the fetal load are detailed,
and show that our australopithecine ancestors had much the same
adaptations.
Katherine K. Whitcome, Liza J. Shapiro and Daniel E. Lieberman
doi:10.1038/nature06342
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNK0Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNL0Ef
Coevolution with viruses drives the evolution of bacterial mutation rates p1079 - 1081
Bacterial cultures experiencing changes in environmental conditions
accumulate mutator strains, presumably to enhance their capability
for adaptive evolution. The presence of bacterial viruses is
demonstrated to have a similar effect, as during co evolution of
Pseudomonas fluorescens and its lytic DNA phage, bacterial mutation
rates significantly increase, resulting in a higher probability of
phage extinction.
Csaba Pal, María D. Maciá, Antonio Oliver, Ira Schachar & Angus Buckling
doi:10.1038/nature06350
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNM0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNN0Eh
Initiation of zebrafish haematopoiesis by the TATA-box-binding
protein-related factor Trf3 p1082 - 1085
It is shown for the first time that a vertebrate specific member of
the TATA box binding protein (TBP) family, called TRF3, controls
haematopoiesis in zebrafish embryogenesis.
Daniel O. Hart, Tamal Raha, Nathan D. Lawson & Michael R. Green
doi:10.1038/nature06349
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNO0Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNP0Ej
CLOCK-mediated acetylation of BMAL1 controls circadian function pp1086 - 1090
The circadian regulator CLOCK has histone acetyltransferase (HAT)
activity that contributes to chromatin-remodelling events during
circadian control of gene expression. Here, CLOCK is shown to acetylate
its heterodimerization partner BMAL1, a step which facilitates
recruitment of CRY1 and promotes transcriptional repression.
Jun Hirayama et al.
doi:10.1038/nature06394
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNQ0Ek
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNR0El
Distinct physiological states of Plasmodium falciparum in
malaria-infected patients p1091 - 1095
This study presents the first large scale transcriptional analysis of
malaria parasites isolated from human patients, and defines three
distinct transcriptional patterns that can be described as active
growth, response to starvation and environmental stress response.
J. P. Daily et al.
doi:10.1038/nature06311
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNS0Em
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNT0En
A viral microRNA functions as an orthologue of cellular miR-155 pp1096 - 1099
Viral microRNAs have been shown to downregulate complementary viral
mRNA targets and to bind to 3prime untranslated regions of host cell
mRNAs to prevent their translation or induce their degradation. This
paper shows that viral miRNAs can also function as orthologues of
cellular miRNAs and downregulate the expression of cellular mRNAs via
target sites that may be evolutionary conserved.
Eva Gottwein et al.
doi:10.1038/nature05992
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNU0Eo
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNV0Ep
Reconstitution of a microtubule plus-end tracking system in vitro p1100 - 1105
A combination of novel surface chemistry and fluorescence microscopy
allows visualization of dynamic microtubules and plus end tracking
proteins in real time. Three microtubule binding proteins from fission
yeast in the in vitro reconstitution system are used, and the results
presented yield new insights into the mechanism of plus end binding
proteins in microtubule dynamics.
Peter Bieling et al.
doi:10.1038/nature06386
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNW0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNX0Er
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J
recombination p1106 - 1110
Adam G. W. Matthews et al.
RAG2, a component of the V(D)J recombinase, has a plant homeodomain
(PHD) domain which specifically recognizes histone H3 trimethylated at
lysine 4 (H3K4me3). A crystal structure of the complex is presented,
and the interaction between RAG2 and H3K4me3 shown to be important for
V(D)J recombination in vivo.
doi:10.1038/nature06431
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNW0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNX0Er
Crystal structure of the plasma membrane proton pump pp1111 - 1114
In plants and fungi, cellular ion homeostasis is powered by the proton
pump, a member of the P-type ATPase family. The first X-ray structure
of the H+-ATPase is presented, and insight into the mechanism by which
protons are transported against an electrochemical gradient is provided.
Bjorn P. Pedersen et al.
doi:10.1038/nature06417
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNY0Es
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNZ0Et
----------------------
TECHNOLOGY FEATURES
----------------------
Small RNAs: Delivering the future pp1117 - 1120
Drugs to treat diseases from cancer to AIDS could soon rely on short
strands of RNA for their effects. But scientists must first work out
how to navigate these fragments around the body.
Nathan Blow reports.
doi:10.1038/4501117a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNa0E1
Small RNAs: The Vehicle Laboratory p1117
doi:10.1038/4501117b
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNb0E2
Small RNAs: The Inside Track p1118
doi:10.1038/4501118a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNc0E3
Small RNAs: Thinking Small p1119
doi:10.1038/4501119a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNd0E4
CORRESPONDENCE
Correction p1120
doi:10.1038/4501120a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNe0E5
Small RNAs: Table of suppliers pp1121 - 1122
doi:10.1038/4501121a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNf0E6
----------------------
NATURE JOBS
----------------------
Prospect
Prospects p1123
Taking ownership of your degree may be the key to a satisfying science
career.
Gene Russo
doi:10.1038/nj7172-1123a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNg0E7
----------------------
FUTURES
----------------------
Recoper p1126
Breathing life into the revolution.
Neal Asher
doi:10.1038/4501126a
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNh0E8
------------------------------
ADVANCE ONLINE PUBLICATION
------------------------------
12 December 2007
Letter
Crude-oil biodegradation via methanogenesis in subsurface petroleum
reservoirs
D. M. Jones et al.
doi:10.1038/nature06484
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNi0EA
09 December 2007
Article
A receptor that mediates the post-mating switch in Drosophila
reproductive behaviour
Nilay Yapici, Young-Joon Kim, Carlos Ribeiro & Barry J. Dickson
doi:10.1038/nature06483
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNj0EB
Letter
Three-dimensional atomic-scale structure of size-selected gold
nanoclusters
Z. Y. Li et al.
doi:10.1038/nature06470
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNk0EC
======================================================================
ADVERTISEMENT
Children's Books Focus
Books for young readers are the focus of a special six-page holiday
season issue of the Books & Arts section of this week's Nature, and
an accompanying podcast. Expert reviewers, their children and their
grandchildren weigh up the different approaches publishers are taking
to communicating science to tomorrow's lab heads and policy makers.
Click below to find out how books are trying to hold their own against
the myriad other information sources now available to budding scientists.
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0BjNl0ED
======================================================================
You have been sent this Table of Contents Alert because you have opted
in to receive it. You can change or discontinue your e-mail alerts at
any time, by modifying your preferences on your nature.com account at:
http://ealerts.nature.com/cgi-bin24/DM/y/eiBe0Xztnp0HjB0Zzu0Ei
(You will need to log in to be recognised as a nature.com registrant).
For further technical assistance, please contact our registration
department: registration@nature.com
For print subscription enquiries, please contact our subscription
department: subscriptions@nature.com
For other enquiries, please contact our customer feedback department:
feedback@nature.com
Nature Publishing Group | 75 Varick Street, 9th Floor | New York |
NY 10013-1917 | USA
Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne -
San Diego - San Francisco - Washington - New York - Boston
(c) Copyright 2007 Nature Publishing Group
=====================================================================
