Researchers they've taken a step forward in stem cell transplants
4 days ago
TORONTO - Scientists at Toronto's Hospital for Sick Children say
they've taken a step forward in stem cell transplant research.
They say they've discovered a gene with properties that allow for
successful transfer of stem cells from human bone marrow into mice.
They also identified the type of cell that expresses the gene (called
SIRPalpha) and is responsible for either destroying or supporting
growth of human blood stem cells.
The researchers hope further studies will lead to the development of
a therapy so more children with blood diseases can receive bone
marrow transplantation.
It may also help provide a genetic test that could be applied to
blood stem cell donors and recipients to increase opportunities for
successful transplants.
The discovery was made by Dr. Jayne Danska in collaboration with Dr.
John Dick, a senior scientist at Ontario Cancer Institute.
Their research is reported in the Nov. 4 online issue of Nature
Immunology.
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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