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World Stem Cell Summit 2010

Wednesday, July 18, 2007

[StemCells] Peptides for skin regeneration - no transplant needed

Peptide targets skin cell growth

By Simon Pitman

Get the latest Market Reports on
Azure Cosmeceuticals
cosmetics
anti-aging

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6/28/2007 - Azure Cosmeceuticals believes it has raised the bar for
peptides with the launch of its new Hydropeptide Transformation
Growth Serum, a product that is said to stimulate skin cell growth.

The company says that it is tapping into recent research that shows
growth factors - human proteins found naturally in the body - are the
best means of fighting the battle against skin wrinkling.

This research has outlined that a variety of growth factors exist,
including epidermal, transforming and vascular endothelial. Indeed,
Azure Cosmeceuticals claims that a number of these growth factors
have been combined in its new serum together with peptide.

Recent scientific research into growth factors has been awarded the
Nobel Prize in medicine for work that created new treatments for skin
burn victims, but now the company says it has furthered that
research, taking into the anti-aging field.

Its new serum contains Transforming Growth Factor- â1 (TGF- â1),
which is said to stimulate cells within damaged skin to 'multiply,
migrate, and differentiate into normal, fully developed cells'.

"They (stem cells) can be stimulated by growth factors without the
need for transplanting; instead, we've just stimulated the cells that
are already there," say James Fallon, professor of anatomy and
neurobiology at UC Irvine and researcher at Stem Cell
Pharmaceuticals, a Seattle-based firm.

The company says that the natural growth factors help to target
photoaging damage when it is so bad the skin cells are beyond repair.
Put basically, the growth factors contained in the formulations step
in to help stimulate the skin's natural repair mechanism, resulting
in the production of new skin tissue and a reduction in fine lines.

Likewise, the serum assists in stimulating new blood vessel formation
with the use of a polypeptide caked Vascular Endothelial Growth
Factor (VEGF).

VEGF is helpful in allowing crucial blood vessel permeability, in
turn enhancing the penetration of topical ingredients, thus making
the serum far more effective.

A recent study by Kline & Company valued the global market for what
it terms 'nutricosmetics' at $1bn. The company forecasts that the
market is set to double over the next five years.

To date, the trend has been more marked in Europe and Japan, with the
North American market not catching on at the same pace.

However, the number of skin care launches within the cosmeceutical or
nutricosmetics category is increasing on virtually a daily basis,
with many of the new launches listing peptides as a key ingredient in
the fight against wrinkles.

In particular Janson Beckett has been one of the leading players in
the US cosmeceuticals field. It currently markets a peptide-based
anti-wrinkle product and more recently extended its market from the
confines of the North American market, to make it available on a
global basis.
http://www.cosmeticsdesign.com/news/ng.asp?n=77762-azure-
cosmeceuticals-cosmetics-anti-aging

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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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