April 2010 Volume 17 Number 4, pp 565 - 732
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EDITORIAL
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Granzymes in disease: bench to bedside
D J Granville
http://links.ealert.nature.com/ctt?kn=35&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
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REVIEWS
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Granzymes and perforin in solid organ transplant rejection
J C Choy
Abstract: http://links.ealert.nature.com/ctt?kn=32&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=29&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
The role of perforin and granzymes in diabetes
H E Thomas, J A Trapani and T W H Kay
Abstract: http://links.ealert.nature.com/ctt?kn=47&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=44&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Control of granzymes by serpins
D Kaiserman and P I Bird
Abstract: http://links.ealert.nature.com/ctt?kn=41&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=39&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Granzymes in age-related cardiovascular and pulmonary diseases
A Hendel, P R Hiebert, W A Boivin, S J Williams and D J Granville
Abstract: http://links.ealert.nature.com/ctt?kn=52&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=50&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Perforin deficiency and susceptibility to cancer
A J Brennan, J Chia, J A Trapani and I Voskoboinik
Abstract: http://links.ealert.nature.com/ctt?kn=88&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=16&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Granzymes in cancer and immunity
S P Cullen, M Brunet and S J Martin
Abstract: http://links.ealert.nature.com/ctt?kn=15&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=14&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Granzyme B cleavage of autoantigens in autoimmunity
E Darrah and A Rosen
Abstract: http://links.ealert.nature.com/ctt?kn=11&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=10&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
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ORIGINAL PAPERS
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Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo
I Lambertz, D Nittner, P Mestdagh, G Denecker, J Vandesompele, M A Dyer and J-C Marine
Abstract: http://links.ealert.nature.com/ctt?kn=8&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=5&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death
E Lafont, D Milhas, S Carpentier, V Garcia, Z-X Jin, H Umehara, T Okazaki, K Schulze-Osthoff, T Levade, H Benoist and B Segui
Abstract: http://links.ealert.nature.com/ctt?kn=1&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=22&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Cytomegaloviruses inhibit Bak- and Bax-mediated apoptosis with two separate viral proteins
M Cam, W Handke, M Picard-Maureau and W Brune
Abstract: http://links.ealert.nature.com/ctt?kn=25&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=26&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
R Kang, D Tang, N E Schapiro, K M Livesey, A Farkas, P Loughran, A Bierhaus, M T Lotze and H J Zeh
Abstract: http://links.ealert.nature.com/ctt?kn=40&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=38&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
PI3K p110[alpha] and p110[beta] have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblasts
R W Matheny and M L Adamo
Abstract: http://links.ealert.nature.com/ctt?kn=46&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=42&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Pim-1 controls NF-[kappa]B signalling by stabilizing RelA/p65
K Nihira, Y Ando, T Yamaguchi, Y Kagami, Y Miki and K Yoshida
Abstract: http://links.ealert.nature.com/ctt?kn=30&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=28&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells
J Gao, M Senthil, B Ren, J Yan, Q Xing, J Yu, L Zhang and J H Yim
Abstract: http://links.ealert.nature.com/ctt?kn=37&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=34&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Studies of the molecular mechanism of caspase-8 activation by solution NMR
N Keller, M G Grutter and O Zerbe
Abstract: http://links.ealert.nature.com/ctt?kn=56&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=57&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
NF45 functions as an IRES trans-acting factor that is required for translation of cIAP1 during the unfolded protein response
T E Graber, S D Baird, P N Kao, M B Mathews and M Holcik
Abstract: http://links.ealert.nature.com/ctt?kn=59&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=64&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
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BOOK REVIEW
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Cell Death
J P Medema, H Walczak, M Hahne and V de Laurenzi
http://links.ealert.nature.com/ctt?kn=62&m=34701488&r=MTc2MDI3ODg3MwS2&b=2&j=Njg5ODE2NTAS1&mt=1&rt=0
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