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| Leading Edge |
| 1. | In This Issue Pages 1199, 1201 |
| Analyses |
| 2. | H1N1: A Mexican Perspective Pages 1203-1205 Laura Vargas-Parada |
| 3. | Overhaul or Overload for French Science? Pages 1206-1208 Karen Dente |
| Commentaries |
| 4. | New Routes into the Human Brain Pages 1209-1211 Martin Raff |
| 5. | Molecules of Madness Pages 1212-1215 Solomon H. Snyder |
| Correspondence |
| 6. | Right-Handed Nucleosome: Myth or Reality? Pages 1216-1217 Christophe Lavelle, Pierre Recouvreux, Hua Wong, Aurélien Bancaud, Jean-Louis Viovy, Ariel Prunell, Jean-Marc Victor |
| 7. | Response: Right-Handed Half-Nucleosomes at Centromeres Pages 1217-1218 Takehito Furuyama, Steven Henikoff |
| Book Review |
| 8. | Microbes Go Manga Page 1219 Zoltan Fehervari |
| Previews |
| 9. | Integrins and Mutant p53 on the Road to Metastasis Pages 1220-1222 Galina Selivanova, Johanna Ivaska |
| 10. | FANCD2 Hurdles the DNA Interstrand Crosslink Pages 1222-1224 George-Lucian Moldovan, Alan D. D'Andrea |
| 11. | Itching for Insight Pages 1224-1226 Michael Bandell, Ardem Patapoutian |
| 12. | Tumor Self-Seeding: Bidirectional Flow of Tumor Cells Pages 1226-1228 Cheuk T. Leung, Joan S. Brugge |
| Review |
| 13. | Metabolism, Cell Surface Organization, and Disease Pages 1229-1241 James W. Dennis, Ivan R. Nabi, Michael Demetriou |
| Articles |
| 14. | The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus Pages 1243-1254 Abraham L. Brass, I-Chueh Huang, Yair Benita, Sinu P. John, Manoj N. Krishnan, Eric M. Feeley, Bethany J. Ryan, Jessica L. Weyer, Louise van der Weyden, Erol Fikrig, David J. Adams, Ramnik J. Xavier, Michael Farzan, Stephen J. Elledge |
| 15. | A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection Pages 1255-1267 Sagi D. Shapira, Irit Gat-Viks, Bennett O.V. Shum, Amelie Dricot, Marciela M. de Grace, Liguo Wu, Piyush B. Gupta, Tong Hao, Serena J. Silver, David E. Root, David E. Hill, Aviv Regev, Nir Hacohen |
| 16. | A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium Pages 1268-1278 Luciano A. Moreira, Iñaki Iturbe-Ormaetxe, Jason A. Jeffery, Guangjin Lu, Alyssa T. Pyke, Lauren M. Hedges, Bruno C. Rocha, Sonja Hall-Mendelin, Andrew Day, Markus Riegler, Leon E. Hugo, Karyn N. Johnson, Brian H. Kay, Elizabeth A. McGraw, Andrew F. van den Hurk, Peter A. Ryan, Scott L. O'Neill |
| 17. | Structural Insight into Translesion Synthesis by DNA Pol II Pages 1279-1289 Feng Wang, Wei Yang |
| 18. | Jarid2/Jumonji Coordinates Control of PRC2 Enzymatic Activity and Target Gene Occupancy in Pluripotent Cells Pages 1290-1302 Jamy C. Peng, Anton Valouev, Tomek Swigut, Junmei Zhang, Yingming Zhao, Arend Sidow, Joanna Wysocka |
| 19. | Jumonji Modulates Polycomb Activity and Self-Renewal versus Differentiation of Stem Cells Pages 1303-1314 Xiaohua Shen, Woojin Kim, Yuko Fujiwara, Matthew D. Simon, Yingchun Liu, Matthew R. Mysliwiec, Guo-Cheng Yuan, Youngsook Lee, Stuart H. Orkin |
| 20. | Tumor Self-Seeding by Circulating Cancer Cells Pages 1315-1326 Mi-Young Kim, Thordur Oskarsson, Swarnali Acharyya, Don X. Nguyen, Xiang H.-F. Zhang, Larry Norton, Joan Massagué |
| 21. | Mutant p53 Drives Invasion by Promoting Integrin Recycling Pages 1327-1341 Patricia A.J. Muller, Patrick T. Caswell, Brendan Doyle, Marcin P. Iwanicki, Ee H. Tan, Saadia Karim, Natalia Lukashchuk, David A. Gillespie, Robert L. Ludwig, Pauline Gosselin, Anne Cromer, Joan S. Brugge, Owen J. Sansom, Jim C. Norman, Karen H. Vousden |
| 22. | Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a Mechanism For Assembly and Membrane Curving Pages 1342-1352 Harry H. Low, Carsten Sachse, Linda A. Amos, Jan Löwe |
| 23. | Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus Pages 1353-1365 Qin Liu, Zongxiang Tang, Lenka Surdenikova, Seungil Kim, Kush N. Patel, Andrew Kim, Fei Ru, Yun Guan, Hao-Jui Weng, Yixun Geng, Bradley J. Undem, Marian Kollarik, Zhou-Feng Chen, David J. Anderson, Xinzhong Dong |
| Theory |
| 24. | Growth Rate-Dependent Global Effects on Gene Expression in Bacteria Pages 1366-1375 Stefan Klumpp, Zhongge Zhang, Terence Hwa |
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