World Stem Cell Summit 2010

Wednesday, December 16, 2009

Nature Reviews Microbiology contents January 2010 Volume 8 Number 1 pp 1-82


January 2010 Volume 8 Number 1

Visit Nature Reviews Microbiology online to browse the journal.

Now available at

Please note that you need to be a subscriber to enjoy full text access
to Nature Reviews Microbiology online. To purchase a subscription,
please visit:

Alternatively, to recommend a subscription to your library, please visit

Nature Reviews Microbiology Impact Factor: 14.310*
*2008 Journal Citation Report (Thomson Reuters, 2009)

=========================== ADVERTISEMENT ===========================

Find over 5,000 vacancies across scientific disciplines as well as the
latest job market news, career advice and more, only at...

ATTENTION EMPLOYERS! Stay up to date with Naturejobs advertising
deadlines and upcoming features: or

US: + 1 800 989 7718
EUR: +44 (0) 20 7843 4961

=========================== ADVERTISEMENT ===========================

Science education has just evolved

Nature Education's Scitable offers peer-reviewed readings, video-based
simulations, and much more. Scitable is a powerful free tool to immerse
your students in genetics.

Build a Scitable classroom today.


This month's FEATURED article:

Molecular mechanisms of Escherichia coli pathogenicity
Matthew A. Croxen and B. Brett Finlay
p26 | doi:10.1038/nrmicro2265


In this issue
p1 | doi:10.1038/nrmicro2292
Thanking all of our authors, referees and readers for their contributions
and interest throughout 2009.

Editorial: Eradicating infectious diseases in 2010
p2 | doi:10.1038/nrmicro2294
Disease eradication programmes are often slower than expected. Several
local and regional eradication programmes had targets for 2010, but
progress towards these goals has been variable.

Innate immunity: Bacteria ensure injury is only skin deep
p3 | doi:10.1038/nrmicro2287
Commensal staphylococci on the skin have a beneficial role in limiting
the activation of potentially harmful inflammation in response to injury.

Bacterial pathogenesis: Position effect of effectors
p4 | doi:10.1038/nrmicro2286
The subcellular localization of a bacterial effector determines its

Bacterial physiology: Bacillus does the two-step
p4 | doi:10.1038/nrmicro2288
The Bacillus subtilis DNA translocases SpoIIIE and SftA have different
but complementary roles at different points in the division cycle.

Immune evasion: Staying undetected
p4 | doi:10.1038/nrmicro2291
Two studies characterize the previously unknown cowpox virus protein
CPXV12, which, along with CPXV203, mediates immune evasion.

Environmental microbiology | Bacterial pathogenesis | Cellular microbiology
p5 | doi:10.1038/nrmicro2289

Environmental microbiology: Viral lipid in bloom
p6 | doi:10.1038/nrmicro2285
Marine viruses produce a glycosphingolipid that triggers programmed
cell death in phytoplankton blooms.

Bacterial secretion: Respiratory remnants
p6 | doi:10.1038/nrmicro2290
The N-tail regions of NarG and BisC contain remnant Tat signal peptides
that can be reactivated into functional Tat export signals.

In the news
p7 | doi:10.1038/nrmicro2293
Our monthly round-up of infectious diseases news, which this month
includes a new model for Entamoeba histolytica infection and the effects
of globalization on pathogen emergence and evolution.

The molecular basis of the host response to lipopolysaccharide
Clare E. Bryant, David R. Spring, Monique Gangloff and Nicholas J. Gay
p8 | doi:10.1038/nrmicro2266
Lipopolysaccharide (LPS) from Gram-negative bacteria is a potent activator
of the innate immune response. Clare Bryant and colleagues discuss recent
exciting data that have revealed the structural basis of the recognition
of LPS by the Toll-like receptor 4-MD2 complex.

Bacterial competition: surviving and thriving in the microbial jungle
Michael E. Hibbing, Clay Fuqua, Matthew R. Parsek and S. Brook Peterson
p15 | doi:10.1038/nrmicro2259
In the diverse microbial communities that are found in most natural
environments, bacteria compete with their neighbours for space and
resources. Here, the authors review the many active mechanisms that
bacteria use to kill or impair their intra- and interspecies competitors.

Molecular mechanisms of Escherichia coli pathogenicity
Matthew A. Croxen and B. Brett Finlay
p26 | doi:10.1038/nrmicro2265
Eight Escherichia coli pathovars have been well characterized to date.
In this Review Matthew Croxen and Brett Finlay discuss recent advances
in our understanding of the virulence of these pathovars that cause
diseases affecting hundreds of millions of people worldwide annually.

Compartmentalized function through cell differentiation in filamentous
Enrique Flores and Antonia Herrero
p39 | doi:10.1038/nrmicro2242
In this Review, Flores and Herrero describe how some cyanobacteria form
multicellular filaments containing cells that are differentiated to
carry out specialized functions. This compartmentalization allows
the bacteria to overcome the problems that are associated with
incompatible metabolic functions such as oxygenic photosynthesis
and N2 fixation.

The cell biology of rabies virus: using stealth to reach the brain
Matthias J. Schnell, James P. McGettigan, Christoph Wirblich and
Amy Papaneri
p51 | doi:10.1038/nrmicro2260
Rabies virus is a neurotropic virus that travels between neurons to
reach the brain. Schnell and colleagues describe the viral life cycle,
from entry into the cell to budding of new virions and spread to neighbouring
cells, and explain how it interferes with the host immune response.

Viruses as vaccine vectors for infectious diseases and cancer
Simon J. Draper and Jonathan L. Heeney
p62 | doi:10.1038/nrmicro2240
Recombinant viruses can act as vaccine vectors by mediating the delivery
of antigens from other infectious agents to a host. In this Review, Draper
and Heeney describe how a better understanding of the relationship between
viruses and the immune system has benefited the use of such viral vectors
in a range of human and veterinary applications.

Mass spectrometry tools for the classification and identification of bacteria
Sascha Sauer and Magdalena Kliem
p74 | doi:10.1038/nrmicro2243
A range of techniques can be used for the identification and classification
of bacteria. However, traditional biochemical and sequence-based approaches
can be labour-intensive and slow. In this Review, Sauer and Kliem discuss
the advantages of mass spectrometry-based procedures for fast and
efficient bacterial identification.

Correspondence: Are correctional facilities amplifying the epidemic of
community-acquired methicillin-resistant Staphylococcus aureus?
Justin T. Okano and Sally Blower
p82 | doi:10.1038/nrmicro2200-c1

=========================== ADVERTISEMENT ===========================

An Emergence & Convergence mini-symposium
Epigenetic Dynamics in the Immune System

San Antonio, TX, USA - February 19, 2010

This mini-symposium aims to foster interdisciplinary discussion, and to
advance our understanding of the ways in which epigenetic factors exert
broad influence over the immune system.

Application deadline: January 4, 2010
To apply today and for more information visit:


You have been sent this Table of Contents Alert because you have opted in to
receive it. You can change or discontinue your e-mail alerts at any time,
by modifying your preferences on your account at:
(You will need to log in to be recognised as a registrant).

For further technical assistance, please contact our registration department:

For print subscription enquiries, please contact our subscription department:

For other enquiries, please contact our customer feedback department:

Nature Publishing Group | 75 Varick Street, 9th Floor | New York |
NY 10013-1917 | USA

Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne -
San Diego - San Francisco - Washington - New York - Boston

(c) Copyright 2010 Nature Publishing Group



Any Comments ?.......


World Time