November 2009 Volume 28 Number 45, pp 3949 - 4040
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JHG Editor's Choice:
Innovative genetic advancement
Journal of Human Genetics (JHG) is proud to feature Editor's Choice:
Innovative genetic advancement - an original collection of articles and
reviews on the most recent, important developments in the field. This
web focus features a variety of articles covering:
- The first genome-wide association study
- Disease susceptibility genes
- Towards personalized medicine
- Population specificity and genome diversity
Access this limited-time web focus today!
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Call for papers!
Submit your best work in the field of oncogenes, including mechanism
of activation, structure and function of encoded proteins; DNA
and RNA tumor viruses and all other aspects of structure and
function.
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ORIGINAL ARTICLES
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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1[alpha]
A Soeda, M Park, D Lee, A Mintz, A Androutsellis-Theotokis, R D McKay, J Engh, T Iwama, T Kunisada, A B Kassam, I F Pollack and D M Park
Abstract: http://links.ealert.nature.com/ctt?kn=36&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=51&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway
A C Hoover, G L Strand, P N Nowicki, M E Anderson, P D Vermeer, A J Klingelhutz, A D Bossler, J V Pottala, WJAJ Hendriks and J H Lee
Abstract: http://links.ealert.nature.com/ctt?kn=52&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=49&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Leupaxin acts as a mediator in prostate carcinoma progression through deregulation of p120catenin expression
S Kaulfusz, S von Hardenberg, S Schweyer, A M Herr, F Laccone, S Wolf and P Burfeind
Abstract: http://links.ealert.nature.com/ctt?kn=50&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=47&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
A Arlt, I Bauer, C Schafmayer, J Tepel, S Sebens Muerkoster, M Brosch, C Roder, H Kalthoff, J Hampe, M P Moyer, U R Folsch and H Schafer
Abstract: http://links.ealert.nature.com/ctt?kn=48&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=42&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints
B Gruhne, R Sompallae and M G Masucci
Abstract: http://links.ealert.nature.com/ctt?kn=44&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=54&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death
D A Tennant, C Frezza, E D MacKenzie, Q D Nguyen, L Zheng, M A Selak, D L Roberts, C Dive, D G Watson, E O Aboagye and E Gottlieb
Abstract: http://links.ealert.nature.com/ctt?kn=11&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=12&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
F van Zijl, M Mair, A Csiszar, D Schneller, G Zulehner, H Huber, R Eferl, H Beug, H Dolznig and W Mikulits
Abstract: http://links.ealert.nature.com/ctt?kn=14&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=16&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
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SHORT COMMUNICATION
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A restricted signature of miRNAs distinguishes APL blasts from normal promyelocytes
S Careccia, S Mainardi, A Pelosi, A Gurtner, D Diverio, R Riccioni, U Testa, E Pelosi, G Piaggio, A Sacchi, S Lavorgna, F Lo-Coco, G Blandino, M Levrero and M G Rizzo
Abstract: http://links.ealert.nature.com/ctt?kn=18&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=20&m=34409589&r=MTc2ODI0Mjc1MwS2&b=2&j=NjA4NDY2NTkS1&mt=1&rt=0
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Launching in 2010: Cell Death & Disease
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