October 2009 Volume 23 Number 10, pp 1689 - 1938
---------------------------------------------------------------------
Cellular & Molecular Immunology
Accepting article submissions
As one of China's premier research journals, Cellular & Molecular
Immunology
http://links.ealert.nature.com/ctt?kn=190&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
benefits communities worldwide by publishing both basic
research and clinical applications in all areas of cellular and
molecular immunology.
Articles that explore novel ideas or unorthodox approaches are
welcome, as long as they are underpinned by conventional scientific
practice and present falsifiable hypotheses that are tested with
empirical methods
and evidence.
Review the Benefits to Authors and Submit your next paper today!
http://links.ealert.nature.com/ctt?kn=189&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
---------------------------------------------------------------------
Why Publish in Leukemia?
Efficient peer-review, hassle-free submission, recognition...
Papers benefit from wide readership through hosting on nature.com
and inclusion in the leading abstracting and indexing services.
Rapid publication is also assured through Advance Online
Publication. To read the full Guide to Authors for Leukemia, visit
http://links.ealert.nature.com/ctt?kn=48&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
----------------------
EDITORIAL
----------------------
Stem-cell collection before high-dose therapy for multiple myeloma:
time has come to raise the standards!
M Mohty
http://links.ealert.nature.com/ctt?kn=40&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
----------------------
SPOTLIGHT REVIEWS
----------------------
Patterns of monoclonal gammopathy of undetermined significance and
multiple myeloma in various ethnic/racial groups: support for
genetic factors in pathogenesis
O Landgren and B M Weiss
Abstract: http://links.ealert.nature.com/ctt?kn=44&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=43&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Class effects of tyrosine kinase inhibitors in the treatment of
chronic myeloid leukemia
F J Giles, M O'Dwyer and R Swords
Abstract: http://links.ealert.nature.com/ctt?kn=36&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=34&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Chronic myeloproliferative diseases with and without the Ph
chromosome: some unresolved issues
J M Goldman, A R Green, T Holyoake, C Jamieson, R Mesa, T Mughal,
F Pellicano, D Perrotti, R Skoda and A M Vannucchi
Abstract: http://links.ealert.nature.com/ctt?kn=39&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=38&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
----------------------
REVIEWS
----------------------
International Myeloma Working Group guidelines for the management of
multiple myeloma patients ineligible for standard high-dose
chemotherapy with autologous stem cell transplantation
A Palumbo, O Sezer, R Kyle, J S Miguel, R Z Orlowski, P Moreau,
R Niesvizky, G Morgan, R Comenzo, P Sonneveld, S Kumar, R Hajek,
S Giralt, S Bringhen, K C Anderson, P G Richardson, M Cavo, F Davies,
J Blade, H Einsele, M A Dimopoulos, A Spencer, A Dispenzieri, T Reiman,
K Shimizu, J H Lee, M Attal, M Boccadoro, M Mateos, W Chen, H Ludwig,
D Joshua, J Chim, V Hungria, I Turesson, B G M Durie and S Lonial on
behalf of the IMWG
Abstract: http://links.ealert.nature.com/ctt?kn=33&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=20&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Altered nucleophosmin transport in acute myeloid leukaemia with mutated
NPM1: molecular basis and clinical implications
B Falini, N Bolli, A Liso, M P Martelli, R Mannucci, S Pileri and
I Nicoletti
Abstract: http://links.ealert.nature.com/ctt?kn=19&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=18&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
----------------------
ORIGINAL ARTICLES
----------------------
MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic
leukemia cells through the pro-apoptotic molecule BIM
A A Rambal, Z L G Panaguiton, L Kramer, S Grant and H Harada
Abstract: http://links.ealert.nature.com/ctt?kn=16&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=15&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Inhibition of KSP by ARRY-520 induces cell cycle block and cell death
via the mitochondrial pathway in AML cells
B Z Carter, D H Mak, R Woessner, S Gross, W D Schober, Z Estrov,
H Kantarjian and M Andreeff
Abstract: http://links.ealert.nature.com/ctt?kn=14&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=12&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Reduced-intensity conditioning allogeneic stem cell transplantation
is a potential therapeutic approach for adults with high-risk acute
lymphoblastic leukemia in remission: results of a prospective
phase 2 study
B-S Cho, S Lee, Y-J Kim, N-G Chung, K-S Eom, H-J Kim, C-K Min, S-G Cho,
D-W Kim, J-W Lee, W-S Min and C-C Kim
Abstract: http://links.ealert.nature.com/ctt?kn=10&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=8&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Thalidomide exerts distinct molecular antileukemic effects and combined
thalidomide/fludarabine therapy is clinically effective in high-risk
chronic lymphocytic leukemia
K Giannopoulos, A Dmoszynska, M Kowal, E Wasik-Szczepanek,
A Bojarska-Junak, J Rolinski, H Dohner, S Stilgenbauer and L Bullinger
Abstract: http://links.ealert.nature.com/ctt?kn=5&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=177&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Rituximab in combination with high-dose methylprednisolone for the
treatment of chronic lymphocytic leukemia
J E Castro, D F James, J D Sandoval-Sus, S Jain, J Bole, L Rassenti
and T J Kipps
Abstract: http://links.ealert.nature.com/ctt?kn=171&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=174&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Interferon-[gamma]-induced neuronal differentiation of human umbilical
cord blood-derived progenitors
H Arien-Zakay, S Lecht, M M Bercu, N Amariglio, G Rechavi, H Galski,
P Lazarovici and A Nagler
Abstract: http://links.ealert.nature.com/ctt?kn=182&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=184&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Cytogenetic profile of de novo acute myeloid leukemia: a study based
on 1432 patients in a single institution of China
Y Cheng, Y Wang, H Wang, Z Chen, J Lou, H Xu, H Wang, W Qian, H Meng,
M Lin and J Jin
Abstract: http://links.ealert.nature.com/ctt?kn=179&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=180&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
SDF-1 and PDGF enhance [alpha]v[beta]5-mediated ERK activation
and adhesion-independent growth of human pre-B cell lines
M Acharya, A L Edkins, B W Ozanne and W Cushley
Abstract: http://links.ealert.nature.com/ctt?kn=187&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=188&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Characterization of BAX inhibitor-1 as a novel leukemia-associated
antigen
S M Schmidt, T Konig, A Bringmann, S Held, K von Schwarzenberg,
A Heine, T A W Holderried, S Stevanovic, F Grunebach and P Brossart
Abstract: http://links.ealert.nature.com/ctt?kn=186&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=141&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Heritable T-cell malignancy models established in a zebrafish
phenotypic screen
J K Frazer, N D Meeker, L Rudner, D F Bradley, A C H Smith,
B Demarest, D Joshi, E E Locke, S A Hutchinson, S Tripp,
S L Perkins and N S Trede
Abstract: http://links.ealert.nature.com/ctt?kn=143&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=146&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Interleukin-21 effectively induces apoptosis in mantle cell lymphoma
through a STAT1-dependent mechanism
P Gelebart, Z Zak, M Anand, J Dien-Bard, H M Amin and R Lai
Abstract: http://links.ealert.nature.com/ctt?kn=147&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=148&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Identification of MNDA as a new marker for nodal marginal zone
lymphoma
G Kanellis, G Roncador, A Arribas, M Mollejo, S Montes-Moreno,
L Maestre, Y Campos-Martin, J L Rios Gonzalez,
J L Martinez-Torrecuadrada, L Sanchez-Verde, R Pajares,
J C Cigudosa, M C Martin and M A Piris
Abstract: http://links.ealert.nature.com/ctt?kn=150&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=151&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Array-based DNA methylation profiling in follicular lymphoma
C O'Riain, D M O'Shea, Y Yang, R Le Dieu, J G Gribben, K Summers,
J Yeboah-Afari, L Bhaw-Rosun, C Fleischmann, C A Mein, T Crook,
P Smith, G Kelly, A Rosenwald, G Ott, E Campo, L M Rimsza,
E B Smeland, W C Chan, N Johnson, R D Gascoyne, S Reimer,
R M Braziel, G W Wright, L M Staudt, T A Lister and J Fitzgibbon
Abstract: http://links.ealert.nature.com/ctt?kn=153&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=155&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Targeting the mammalian target of Rapamycin to inhibit VEGF and
cytokines for the treatment of primary effusion lymphoma
P Gasperini and G Tosato
Abstract: http://links.ealert.nature.com/ctt?kn=156&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=27&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Chromosomal imbalances and partial uniparental disomies in primary
central nervous system lymphoma
H Schwindt, I Vater, M Kreuz, M Montesinos-Rongen, A Brunn, J Richter,
S Gesk, O Ammerpohl, O D Wiestler, D Hasenclever, M Deckert and
R Siebert
Abstract: http://links.ealert.nature.com/ctt?kn=29&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=30&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
STAT6 and STAT1 are essential antagonistic regulators of cell survival
in classical Hodgkin lymphoma cell line
D Baus, F Nonnenmacher, S Jankowski, C Doring, C Brautigam,
M Frank, M-L Hansmann and E Pfitzner
Abstract: http://links.ealert.nature.com/ctt?kn=31&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=21&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
The effects of JNJ-26481585, a novel hydroxamate-based histone
deacetylase inhibitor, on the development of multiple myeloma in
the 5T2MM and 5T33MM murine models
S Deleu, M Lemaire, J Arts, E Menu, E Van Valckenborgh, P King,
I Vande Broek, H De Raeve, B Van Camp, P Croucher and
K Vanderkerken
Abstract: http://links.ealert.nature.com/ctt?kn=22&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=24&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
International myeloma working group (IMWG) consensus statement and
guidelines regarding the current status of stem cell collection
and high-dose therapy for multiple myeloma and the role of
plerixafor (AMD 3100)
S Giralt, E A Stadtmauer, J L Harousseau, A Palumbo, W Bensinger,
R L Comenzo, S Kumar, N C Munshi, A Dispenzieri, R Kyle, G Merlini,
J San Miguel, H Ludwig, R Hajek, S Jagannath, J Blade, S Lonial,
M A Dimopoulos, H Einsele, B Barlogie, K C Anderson, M Gertz, M Attal,
P Tosi, P Sonneveld, M Boccadoro, G Morgan, O Sezer, M V Mateos,
M Cavo, D Joshua, I Turesson, W Chen, K Shimizu, R Powles,
P G Richardson, R Niesvizky, S V Rajkumar and B G M Durie on behalf
of the IMWG
Abstract: http://links.ealert.nature.com/ctt?kn=26&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=170&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Genetic polymorphisms of EPHX1, Gsk3[beta], TNFSF8 and myeloma cell
DKK-1 expression linked to bone disease in myeloma
B G M Durie, B Van Ness, C Ramos, O Stephens, M Haznadar, A Hoering,
J Haessler, M S Katz, G R Mundy, R A Kyle, G J Morgan, J Crowley,
B Barlogie and J Shaughnessy
Abstract: http://links.ealert.nature.com/ctt?kn=173&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=159&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
----------------------
LETTERS TO THE EDITOR
----------------------
Erythroid/B-cell biphenotypic acute leukemia first case report
J C Lee, S Yang, Y Zou and L Joseph
http://links.ealert.nature.com/ctt?kn=162&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
The 'GGCC' haplotype of JAK2 confers susceptibility to JAK2 exon
12 mutation-positive polycythemia vera
D Olcaydu, R C Skoda, R Looser, S Li, M Cazzola, D Pietra,
F Passamonti, E Lippert, S Carillo, F Girodon, A Vannucchi,
N S Reading, J T Prchal, C Ay, I Pabinger, H Gisslinger and
R Kralovics
http://links.ealert.nature.com/ctt?kn=160&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
The 1170 A-P single-nucleotide polymorphism (SNP) in the Her-2/neu
protein (HER2) as a minor histocompatibility antigen (mHag)
L Wenandy, T Kollgaard, A Letsch, R S Andersen, D Stather,
T Seremet, I M Svane, L Vindelov, M H Andersen and P thor Straten
http://links.ealert.nature.com/ctt?kn=167&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
SNP analyses in cytarabine metabolizing enzymes in AML patients
and their impact on treatment response and patient survival:
identification of CDA SNP C-451T as an independent prognostic
parameter for survival
U Mahlknecht, C-L Dransfeld, N Bulut, M Kramer, C Thiede,
G Ehninger and M Schaich
http://links.ealert.nature.com/ctt?kn=165&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Src family kinase gene targets during myeloid differentiation:
identification of the EGR-1 gene as a direct target
J E Jones, L Wang, P L Kropf, R Duan and D E Johnson
http://links.ealert.nature.com/ctt?kn=169&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Vorinostat interferes with Wnt and NF-[kappa]B pathways in the M-07e
cell line
S Galimberti, M Canestraro, R Maffei, R Marasca, F Guerrini,
S Piaggi, E Ciabatti and M Petrini
http://links.ealert.nature.com/ctt?kn=168&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
---------------------------------------------------------------------
Launching in 2010: Cell Death & Disease
http://links.ealert.nature.com/ctt?kn=72&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
Online submission is now open at
http://links.ealert.nature.com/ctt?kn=86&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
- Cell Death & Disease focuses on the translational implications of
cell death
- Brought to you from the same editorial team as Cell Death &
Differentiation
- Top-quality Editors: Guido Kroemer, Gerry Melino, Pierluigi
Nicotera
- Efficient peer-review and fast publication
Contributions of broad biological interest and impact are especially
encouraged. Submit today
http://links.ealert.nature.com/ctt?kn=88&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
=====================================================================
You have been sent this Table of Contents Alert because you have opted in to receive it.
You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at:
http://links.ealert.nature.com/ctt?kn=67&m=34231133&r=MTc2MzIyNTA1NQS2&b=2&j=NTk0MzQ1MjUS1&mt=1&rt=0
(You will need to log in to be recognised as a nature.com registrant).
For further technical assistance, please contact our registration department:
registration@nature.com
For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com
For other enquiries, please contact customer feedback department:
feedback@nature.com
Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA
Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne - San Diego - San Francisco - Washington - New York - Boston
Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS.
© Copyright 2009 Nature Publishing Group
=====================================================================
