September 2009 Volume 23 Number 9, pp 1535 - 1688
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Vaccine Strategies in the 21st Century
ICB: Special Feature & Web Focus
Immunology & Cell Biology is proud to present Vaccine Strategies
in the 21st Century - a collection of articles that introduce
research on a new generation of vaccines which are logically designed
and evaluated. The accompanying web focus delves deeper into vaccine
research, placing recent discoveries into context.
Access Vaccine Strategies in the 21st Century online today!
http://links.ealert.nature.com/ctt?kn=72&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
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EDITORIAL
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The role of monocytes-macrophages in vasculogenesis in multiple
myeloma
D Ribatti and A Vacca
Abstract: http://links.ealert.nature.com/ctt?kn=65&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=7&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
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REVIEWS
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Pharmacokinetic/pharmacodynamic correlation and blood-level
testing in imatinib therapy for chronic myeloid leukemia
J E Cortes, M J Egorin, F Guilhot, M Molimard and F-X Mahon
Abstract: http://links.ealert.nature.com/ctt?kn=9&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=11&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
International myeloma working group consensus statement and
guidelines regarding the current role of imaging techniques
in the diagnosis and monitoring of multiple Myeloma
M Dimopoulos, E Terpos, R L Comenzo, P Tosi, M Beksac, O Sezer,
D Siegel, H Lokhorst, S Kumar, S V Rajkumar, R Niesvizky,
L A Moulopoulos and B G M Durie On behalf of the IMWG
Abstract: http://links.ealert.nature.com/ctt?kn=12&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=2&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
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ORIGINAL ARTICLES
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Activation of p53 by MDM2 antagonists has differential apoptotic
effects on Epstein-Barr virus (EBV)-positive and EBV-negative
Burkitt's lymphoma cells
B Renouf, E Hollville, A Pujals, C Tetaud, J Garibal and J Wiels
Abstract: http://links.ealert.nature.com/ctt?kn=4&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=5&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
A novel treatment strategy targeting polo-like kinase 1 in
hematological malignancies
T Ikezoe, J Yang, C Nishioka, Y Takezaki, T Tasaka, K Togitani,
H P Koeffler and A Yokoyama
Abstract: http://links.ealert.nature.com/ctt?kn=6&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=77&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Involvement of mast cells by the malignant process in patients with
Philadelphia chromosome negative myeloproliferative neoplasms
J Wang, T Ishii, W Zhang, S Sozer, Y Dai, J Mascarenhas, V Najfeld,
Z J Zhao, R Hoffman, N Wisch and M Xu
Abstract: http://links.ealert.nature.com/ctt?kn=57&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=59&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Monoclonal antibodies against IREM-1: potential for targeted
therapy of AML
W Korver, X Zhao, S Singh, C Pardoux, J Zhao, M L Guzman, S Sen,
S Yonkovich, S Liu, X Zhan, N Tomasevic, C Zhou, D Gros, C T Jordan,
J Gotlib, E D Hsi and A Abo
Abstract: http://links.ealert.nature.com/ctt?kn=54&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=56&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
AML1-ETO9a is correlated with C-KIT overexpression/mutations and
indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2
B Jiao, C-F Wu, Y Liang, H-M Chen, S-M Xiong, B Chen, J-Y Shi,
Y-Y Wang, J-H Wang, Y Chen, J-M Li, L-J Gu, J-Y Tang, Z-X Shen,
B-W Gu, W-L Zhao, Z Chen and S-J Chen
Abstract: http://links.ealert.nature.com/ctt?kn=62&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=64&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Accurate detection of uniparental disomy and microdeletions by SNP
array analysis in myelodysplastic syndromes with normal cytogenetics
S Heinrichs, R V Kulkarni, C E Bueso-Ramos, R L Levine, M L Loh,
C Li, D Neuberg, S M Kornblau, J-P Issa, D G Gilliland,
G Garcia-Manero, H M Kantarjian, E H Estey and A T Look
Abstract: http://links.ealert.nature.com/ctt?kn=60&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=61&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
The gatekeeper mutation T315I confers resistance against small
molecules by increasing or restoring the ABL-kinase activity
accompanied by aberrant transphosphorylation of endogenous
BCR, even in loss-of-function mutants of BCR/ABL
A A Mian, M Schull, Z Zhao, C Oancea, A Hundertmark, T Beissert,
O G Ottmann and M Ruthardt
Abstract: http://links.ealert.nature.com/ctt?kn=46&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=44&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
BCR-ABL promotes neutrophil differentiation in the chronic phase
of chronic myeloid leukemia by downregulating c-Jun expression
S Kobayashi, F Kimura, T Ikeda, Y Osawa, H Torikai, A Kobayashi,
K Sato and K Motoyoshi
Abstract: http://links.ealert.nature.com/ctt?kn=29&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=38&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Dasatinib-associated major molecular responses in patients with
chronic myeloid leukemia in chronic phase following imatinib
failure: response dynamics and predictive value
A Hochhaus, M C Muller, J Radich, S Branford, H M Kantarjian,
B Hanfstein, P Rousselot, D-W Kim, J H Lipton, E Bleickardt,
A Lambert and T P Hughes
Abstract: http://links.ealert.nature.com/ctt?kn=39&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=40&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
WT1 peptide-specific T cells generated from peripheral blood of
healthy donors: possible implications for adoptive immunotherapy
after allogeneic stem cell transplantation
G Weber, J Karbach, S Kuci, H Kreyenberg, A Willasch,
E Koscielniak, T Tonn, T Klingebiel, W S Wels, E Jager
and P Bader
Abstract: http://links.ealert.nature.com/ctt?kn=41&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=31&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Membrane microparticles mediate transfer of P-glycoprotein to drug
sensitive cancer cells
M Bebawy, V Combes, E Lee, R Jaiswal, J Gong, A Bonhoure
and G E R Grau
Abstract: http://links.ealert.nature.com/ctt?kn=32&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=35&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Enhanced expression of FHL2 leads to abnormal myelopoiesis in vivo
Z Qian, L Mao, A A Fernald, H Yu, R Luo, Y Jiang, J Anastasi,
P J Valk, R Delwel and M M Le Beau
Abstract: http://links.ealert.nature.com/ctt?kn=36&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=24&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Wnt signaling pathway is epigenetically regulated by methylation of
Wnt antagonists in acute myeloid leukemia
A Valencia, J Roman-Gomez, J Cervera, E Such, E Barragan,
P Bolufer, F Moscardo, G F Sanz and M A Sanz
Abstract: http://links.ealert.nature.com/ctt?kn=1&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=3&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
STAT3 transcription factor is constitutively activated and is
oncogenic in nasal-type NK/T-cell lymphoma
P Coppo, V Gouilleux-Gruart, Y Huang, H Bouhlal, H Bouamar,
S Bouchet, C Perrot, V Vieillard, P Dartigues, P Gaulard,
F Agbalika, L Douay, K Lassoued and N-C Gorin
Abstract: http://links.ealert.nature.com/ctt?kn=18&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=19&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Ascorbic acid inhibits antitumor activity of bortezomib in vivo
G Perrone, T Hideshima, H Ikeda, Y Okawa, E Calabrese, G Gorgun,
L Santo, D Cirstea, N Raje, D Chauhan, M Baccarani, M Cavo
and K C Anderson
Abstract: http://links.ealert.nature.com/ctt?kn=16&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=17&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
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LETTER TO THE EDITOR
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Efficacy of dasatinib in conjunction with [alpha]-interferon
for the treatment of imatinib-resistant and dasatinib-resistant
Ph+ acute lymphoblastic leukemia
G Visani, P Piccaluga, M Malagola and A Isidori
Abstract: http://links.ealert.nature.com/ctt?kn=14&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=15&m=34023060&r=MTc2MzIyNTA1NQS2&b=2&j=NTc3NTAyNTES1&mt=1&rt=0
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