August 2009 Volume 23 Number 8, pp 1373 - 1534
---------------------------------------------------------------------
Announcing the NEW Leukemia impact factor: 8.634*
4/62 in Hematology
9/141 in Oncology
*2008 Journal Citation Report (Thomson Reuters, 2009)
http://links.ealert.nature.com/ctt?kn=12&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
---------------------------------------------------------------------
Why Publish in Leukemia?
Efficient peer-review, hassle-free submission, recognition...
Papers benefit from wide readership through hosting on nature.com and
inclusion in the leading abstracting and indexing services.
Rapid publication is also assured through Advance Online Publication.
To read the full Guide to Authors for Leukemia, visit
http://links.ealert.nature.com/ctt?kn=58&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
----------------------
EDITORIAL
----------------------
Iron chelation therapy in myelodysplastic syndrome[thinsp][mdash]
[thinsp]Cui bono?
A Tefferi and R M Stone
http://links.ealert.nature.com/ctt?kn=81&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
----------------------
CONCISE REVIEW
----------------------
NOTCH inhibition and glucocorticoid therapy in T-cell acute
lymphoblastic leukemia
P J Real and A A Ferrando
Abstract: http://links.ealert.nature.com/ctt?kn=32&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=76&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
----------------------
ORIGINAL ARTICLES
----------------------
The CXCR4 antagonist 4F-benzoyl-TN14003 stimulates the recovery
of the bone marrow after transplantation
M Abraham, K Beider, H Wald, I D Weiss, D Zipori, E Galun,
A Nagler, O Eizenberg and A Peled
Abstract: http://links.ealert.nature.com/ctt?kn=85&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=72&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
A novel AML-selective TRAIL fusion protein that is superior
to Gemtuzumab Ozogamicin in terms of in vitro selectivity,
activity and stability
B ten Cate, E Bremer, M de Bruyn, T Bijma, D Samplonius,
M Schwemmlein, G Huls, G Fey and W Helfrich
Abstract: http://links.ealert.nature.com/ctt?kn=5&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=13&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor
dasatinib therapy
S Mustjoki, M Ekblom, T P Arstila, I Dybedal, P K Epling-Burnette,
F Guilhot, H Hjorth-Hansen, M Hoglund, P Kovanen, T Laurinolli,
J Liesveld, R Paquette, J Pinilla-Ibarz, A Rauhala, N Shah,
B Simonsson, M Sinisalo, J L Steegmann, L Stenke and K Porkka
Abstract: http://links.ealert.nature.com/ctt?kn=17&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=44&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Increased risk for CNS relapse in pre-B cell leukemia with the
t(1;19)/TCF3-PBX1
S Jeha, D Pei, S C Raimondi, M Onciu, D Campana, C Cheng,
J T Sandlund, R C Ribeiro, J E Rubnitz, S C Howard, J R Downing,
W E Evans, M V Relling and C-H Pui
Abstract: http://links.ealert.nature.com/ctt?kn=92&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=14&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Combination of cladribine and cytarabine is effective for
childhood acute myeloid leukemia: results of the St Jude
AML97 trial
J E Rubnitz, K R Crews, S Pounds, S Yang, D Campana, V V Gandhi,
S C Raimondi, J R Downing, B I Razzouk, C-H Pui and R C Ribeiro
Abstract: http://links.ealert.nature.com/ctt?kn=29&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=22&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and
downstream signaling in pediatric T-cell acute lymphoblastic
leukemia: a report from the Children's Oncology Group
A Larson Gedman, Q Chen, S Kugel Desmoulin, Y Ge, K LaFiura,
C L Haska, C Cherian, M Devidas, S B Linda, J W Taub and
L H Matherly
Abstract: http://links.ealert.nature.com/ctt?kn=37&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=53&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
RUNX1 mutations are frequent in chronic myelomonocytic leukemia and
mutations at the C-terminal region might predict acute myeloid
leukemia transformation
M-C Kuo, D-C Liang, C-F Huang, Y-S Shih, J-H Wu, T-L Lin
and L-Y Shih
Abstract: http://links.ealert.nature.com/ctt?kn=45&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=82&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway
R Naughton, C Quiney, S D Turner and T G Cotter
Abstract: http://links.ealert.nature.com/ctt?kn=15&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=90&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
CYT387, a selective JAK1/JAK2 inhibitor: in vitro assessment
of kinase selectivity and preclinical studies using cell lines
and primary cells from polycythemia vera patients
A Pardanani, T Lasho, G Smith, C J Burns, E Fantino and A Tefferi
Abstract: http://links.ealert.nature.com/ctt?kn=24&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=74&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Inhibitory effects of omacetaxine on leukemic stem cells and
BCR-ABL-induced chronic myeloid leukemia and acute lymphoblastic
leukemia in mice
Y Chen, Y Hu, S Michaels, D Segal, D Brown and S Li
Abstract: http://links.ealert.nature.com/ctt?kn=54&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=71&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Defective engraftment of C3aR-/- hematopoietic stem progenitor cells
shows a novel role of the C3a-C3aR axis in bone marrow homing
M Wysoczynski, R Reca, H Lee, W Wu, J Ratajczak and M Z Ratajczak
Abstract: http://links.ealert.nature.com/ctt?kn=42&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=18&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
PML-RAR[alpha] initiates leukemia by conferring properties of
self-renewal to committed promyelocytic progenitors
S Wojiski, F C Guibal, T Kindler, B H Lee, J L Jesneck, A Fabian,
D G Tenen and D G Gilliland
Abstract: http://links.ealert.nature.com/ctt?kn=3&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=49&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Standardization of WT1 mRNA quantitation for minimal residual
disease monitoring in childhood AML and implications of WT1 gene
mutations: a European multicenter study
A M Willasch, B Gruhn, T Coliva, M Kalinova, G Schneider, H Kreyenberg,
D Steinbach, G Weber, I H I M Hollink, C M Zwaan, A Biondi,
V H J van der Velden, D Reinhardt, G Cazzaniga, P Bader and J Trka
on behalf of the European Study Group on WT1 Expression in
Childhood AML. Frankfurt, Jena (Germany), Monza (Italy), Prague
(Czech Republic)
Abstract: http://links.ealert.nature.com/ctt?kn=62&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=38&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and
Ubc13 interacting domains
J A Marteijn, L T van der Meer, J J Smit, S M Noordermeer, W Wissink,
P Jansen, H G Swarts, R G Hibbert, T de Witte, T K Sixma, J H Jansen
and B A van der Reijden
Abstract: http://links.ealert.nature.com/ctt?kn=57&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=87&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
New insights to the MLL recombinome of acute leukemias
C Meyer, E Kowarz, J Hofmann, A Renneville, J Zuna, J Trka,
R Ben Abdelali, E Macintyre, E De Braekeleer, M De Braekeleer,
E Delabesse, M P de Oliveira, H Cave, E Clappier, J J M van Dongen,
B V Balgobind, M M van den Heuvel-Eibrink, H B Beverloo,
R Panzer-Grumayer, A Teigler-Schlegel, J Harbott, E Kjeldsen,
S Schnittger, U Koehl, B Gruhn, O Heidenreich, L C Chan, S F Yip,
M Krzywinski, C Eckert, A Moricke, M Schrappe, C N Alonso, B W Schafer,
J Krauter, D A Lee, U zur Stadt, G Te Kronnie, R Sutton, S Izraeli,
L Trakhtenbrot, L Lo Nigro, G Tsaur, L Fechina, T Szczepanski, S Strehl,
D Ilencikova, M Molkentin, T Burmeister, T Dingermann, T Klingebiel
and R Marschalek
Abstract: http://links.ealert.nature.com/ctt?kn=1&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=8&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form
of the tyrosine kinase Lyn in chronic myelogenous leukemia cells
P Gamas, S Marchetti, A Puissant, S Grosso, A Jacquel, P Colosetti,
J-M Pasquet, F-X Mahon, J-P Cassuto and P Auberger
Abstract: http://links.ealert.nature.com/ctt?kn=20&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=70&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
The proteasome inhibitor bortezomib interacts synergistically with
the histone deacetylase inhibitor suberoylanilide hydroxamic acid
to induce T-leukemia/lymphoma cells apoptosis
Q-L Zhang, L Wang, Y-W Zhang, X-X Jiang, F Yang, W-L Wu, A Janin,
Z Chen, Z-X Shen, S-J Chen and W-L Zhao
Abstract: http://links.ealert.nature.com/ctt?kn=30&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=59&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Mesenchymal stem cells from multiple myeloma patients display distinct
genomic profile as compared with those from normal donors
M Garayoa, J L Garcia, C Santamaria, A Garcia-Gomez, J F Blanco,
A Pandiella, J M Hernandez, F M Sanchez-Guijo, M-C del Canizo,
N C Gutierrez and J F San Miguel
Abstract: http://links.ealert.nature.com/ctt?kn=86&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=91&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Is the international staging system superior to the Durie-Salmon
staging system? A comparison in multiple myeloma patients
undergoing autologous transplant
P N Hari, M-J Zhang, V Roy, W S Perez, A Bashey, L B To, G Elfenbein,
C O Freytes, R P Gale, J Gibson, R A Kyle, H M Lazarus, P L McCarthy,
G A Milone, S Pavlovsky, D E Reece, G Schiller, J Vela-Ojeda,
D Weisdorf and D Vesole
Abstract: http://links.ealert.nature.com/ctt?kn=35&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=27&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
=====================================================================
Nature Reviews Cancer
2008 Impact Factor: 30.762*
For its 5th consecutive year, Nature Reviews Cancer is the number one
cited monthly review journal in oncology. Ensure you have access to
the 'must-read' review journal of cancer researchers worldwide.
Subscribe today at a 20% discount:
http://links.ealert.nature.com/ctt?kn=48&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
Recommend to your library:
http://links.ealert.nature.com/ctt?kn=65&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
*2008 Journal Citation Reports (Thomson Reuters, 2009)
---------------------------------------------------------------------
You have been sent this Table of Contents Alert because you have opted in to receive it.
You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at:
http://links.ealert.nature.com/ctt?kn=31&m=33851483&r=MTc2MzIyNTA1NQS2&b=2&j=NTY1OTAxNjgS1&mt=1&rt=0
(You will need to log in to be recognised as a nature.com registrant).
For further technical assistance, please contact our registration department:
registration@nature.com
For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com
For other enquiries, please contact customer feedback department:
feedback@nature.com
Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA
Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne - San Diego - San Francisco - Washington - New York - Boston
Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS.
© Copyright 2009 Nature Publishing Group
=====================================================================
