Mesenchymal Stem Cells Presenting Antigen

View this message online Hello manoj kumar valluru, A very interesting patent was issued last week, #7,553,661, covering the use of mesenchymal stem cells as antigen presenting cells.  In order to induce antigen presenting function the cells are stimulated with interferon gamma.  Uses for this patent may include tolerogenic vaccines.  Patent #7,553,663 granted to Blasticon covers the treatment of liver failure using hepatocytes generated from dedifferentiated monocytes.  This IP seems a little related to with Opexa is working on.  It will be interesting to see whether there will be any interactions between these companies. Noteworthy publications last week included a paper by Herr et al demonstrating that apoptotic bodies induce macrophages to secrete angiogenic factors...this makes us wonder...could we simply just use extracorporeal ozonization or photopheresis to achieve angiogenesis clinically?  People in the alternative medicine community have been saying this for decades now.   Stromal antigen-presenting cells and use thereof     Patent Number: 7,553,661 Assignee | Inventor Mesenchymal stem cells are known to possess a variety of immune modulatory activities such as suppression of allogeneic responses, as well as induction of T regulatory cells.  Mechanisms include expression of IDO and HLA-G.  Mesenchymal stem cells...[Read More] Ask a question OR leave your comments.     Apoptotic Cells Secrete Angiogenic Factors Saturday June 27th, 2009 @ 03:54:59 EST It is a medical mystery why approaches such as extracorporeal ozone therapy or even photopheresis seem to have therapeutic effects in certain situations.  One possibility is that stressing of cells outside of the body causes formation of apoptotic bodies, with the apoptotic bodies having a therapeutic...[Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News   Media Partnerships (NEW)   NEWS - WHAT'S GETTING ATTENTION?     Bone Marrow Stem Cells for Renal Failure | 4 Comment(s)     RECENTLY ADDED PATENTS     Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,553,663) Assignee | Inventor | Ask a question OR leave your comments     Stromal antigen-presenting cells and use thereof (7,553,661) Assignee | Inventor | Ask a question OR leave your comments     Directed in vitro differentiation of marrow stromal cells into neural cell progenitors (7,547,545) Assignee | Inventor | Ask a question OR leave your comments     Progenitor cells from wharton's jelly of human umbilical cord (7,547,546) Assignee | Inventor | Ask a question OR leave your comments     Methods for identifying factors for differentiating definitive endoderm (7,541,185) Assignee | Inventor | Ask a question OR leave your comments     Method of generating human retinal progenitors from embryonic stem cells (7,541,186) Assignee | Inventor | Ask a question OR leave your comments     Growth and differentiation of adult muscle stem cells with activators or inhibitors of Wnt signaling (7,541,183) Assignee | Inventor | Ask a question OR leave your comments     Angiogenically effective unit dose of FGF-2 and method of use (7,541,333) Assignee | Inventor | Ask a question OR leave your comments     Stem cells and their use in transplantation (7,537,756) Assignee | Inventor | Ask a question OR leave your comments     Method of expanding undifferentiated hemopoietic stem cells (7,534,609) Assignee | Inventor | Ask a question OR leave your comments     View all 1430 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     Apoptotic Cells Secrete Angiogenic Factors 5 days ago     Hair Stem Cells for Injured Nerves June 10th     Pulmonary Fibrosis Treated by Mesenchymal Stem Cells June 8th     Free bone allograft prevents acute immune reaction May 26th     G-CSF Makes You Smarter May 16th     Read more news on StemCellPatents.com     LATEST JOBS POSTS     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com. Media Partnerships (NEW) (BETA) ------------------------------------------------------------ To unsubscribe, click here. Delivered: Thursday July 2nd, 2009 @ 14:45:39 EST