08 July 2009 Volume 28 Number 13, pp 1825 - 1987
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HAVE YOU SEEN ...?
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Nonconformity in ubiquitin compliance pp1825 - 1827
Inbal Ziv, Oded Kleifeld and Michael Glickman
doi:10.1038/emboj.2009.132
Abstract: http://links.ealert.nature.com/ctt?kn=110&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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A histone code for the DNA damage response in mammalian cells[quest] pp1828 - 1830
Armelle Corpet and Genevieve Almouzni
doi:10.1038/emboj.2009.180
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ARTICLES
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A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism pp1831 - 1842
Yuxin Mao, Daniel M Balkin, Roberto Zoncu, Kai S Erdmann, Livia Tomasini,
Fenghua Hu, Moonsoo M Jin, Michael E Hodsdon and Pietro De Camilli
doi:10.1038/emboj.2009.155
Abstract: http://links.ealert.nature.com/ctt?kn=67&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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JNK signalling modulates intestinal homeostasis and tumourigenesis in mice pp1843 - 1854
Rocio Sancho, Abdolrahman S Nateri, Amaya Garcia de Vinuesa, Cristina Aguilera,
Emma Nye, Bradley Spencer-Dene and Axel Behrens
doi:10.1038/emboj.2009.153
Abstract: http://links.ealert.nature.com/ctt?kn=31&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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The fungal RNA-binding protein Rrm4 mediates long-distance transport of ubi1 and rho3 mRNAs pp1855 - 1866
Julian König, Sebastian Baumann, Janine Koepke, Thomas Pohlmann,
Kathi Zarnack and Michael Feldbrügge
doi:10.1038/emboj.2009.145
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S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains pp1867 - 1877
Hyoung Tae Kim, Kwang Pyo Kim, Tomoaki Uchiki, Steven P Gygi and Alfred L Goldberg
doi:10.1038/emboj.2009.115
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Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells pp1878 - 1889
Jorrit V Tjeertes, Kyle M Miller and Stephen P Jackson
doi:10.1038/emboj.2009.119
Abstract: http://links.ealert.nature.com/ctt?kn=89&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation pp1890 - 1903
Zhengquan Yu, Jaana Mannik, Amelia Soto, Kevin K Lin and Bogi Andersen
doi:10.1038/emboj.2009.142
Abstract: http://links.ealert.nature.com/ctt?kn=9&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf pp1904 - 1915
Xiaohua Su, Min Soon Cho, Young-Jin Gi, Bernard A Ayanga, Charles J Sherr and Elsa R Flores
doi:10.1038/emboj.2009.151
Abstract: http://links.ealert.nature.com/ctt?kn=29&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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The Apaf-1[bull]procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer pp1916 - 1925
Srinivas Malladi, Madhavi Challa-Malladi, Howard O Fearnhead and Shawn B Bratton
doi:10.1038/emboj.2009.152
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MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway pp1926 - 1939
Francesca Mancini, Giusy Di Conza, Marsha Pellegrino, Cinzia Rinaldo, Andrea Prodosmo,
Simona Giglio, Igea D'Agnano, Fulvio Florenzano, Lara Felicioni, Fiamma Buttitta,
Antonio Marchetti, Ada Sacchi, Alfredo Pontecorvi, Silvia Soddu and Fabiola Moretti
doi:10.1038/emboj.2009.154
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Noc protein binds to specific DNA sequences to coordinate cell division with chromosome segregation pp1940 - 1952
Ling Juan Wu, Shu Ishikawa, Yoshikazu Kawai, Taku Oshima, Naotake Ogasawara and Jeff Errington
doi:10.1038/emboj.2009.144
Abstract: http://links.ealert.nature.com/ctt?kn=53&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic pp1953 - 1964
Catherine A Regni, Rebecca F Roush, Darcie J Miller, Amanda Nourse,
Christopher T Walsh and Brenda A Schulman
doi:10.1038/emboj.2009.146
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Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt pp1965 - 1977
Clemens Grimm, Raquel Matos, Nga Ly-Hartig, Ulrich Steuerwald, Doris Lindner,
Vladimir Rybin, Jürg Müller and Christoph W Müller
doi:10.1038/emboj.2009.147
Abstract: http://links.ealert.nature.com/ctt?kn=57&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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3D architecture of DNA Pol [alpha] reveals the functional core of multi-subunit replicative polymerases pp1978 - 1987
Sebastian Klinge, Rafael Núñez-Ramírez, Oscar Llorca and Luca Pellegrini
doi:10.1038/emboj.2009.150
Abstract: http://links.ealert.nature.com/ctt?kn=64&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
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Protein modifications: beyond the usual suspects
http://links.ealert.nature.com/ctt?kn=25&m=33545931&r=MTc2ODY3NTU2NQS2&b=2&j=NTI4MDUyMTkS1&mt=1&rt=0
EMBO reports web focus
Get a sense of the molecular diversity that exists within cells!
This series of comprehensive and engaging reviews highlights the complexity
of post-translational protein modifications. Leading experts analyze atypical
ubiquitin-chain formation, ATGylation, polyglutamylation, neddylation, and Urmylation,
and update our knowledge on poly(ADP-ribosyl)ation and O-GlcNAcylation.
A complex but important topic to understand!
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