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| Leading Edge |
| 1. | In This Issue Pages 1161, 1163 |
| 2. | Developmental Biology Select Pages 1165, 1167 |
| Analysis |
| 3. | Seeing Green in Conference Season Pages 1169-1171 Lila Guterman |
| Correspondence |
| 4. | Common Ancestry of the CENP-A Chaperones Scm3 and HJURP Pages 1173-1174 Luis Sanchez-Pulido, Alison L. Pidoux, Chris P. Ponting, Robin C. Allshire |
| Book Review |
| 5. | Glycobiology: Moving into the Mainstream Pages 1175-1176 Raymond A. Dwek |
| Previews |
| 6. | GABA Keeps Up an Appetite for Life Pages 1177-1179 Marcelo O. Dietrich, Tamas L. Horvath |
| 7. | Ironing Out a Midlife Crisis Pages 1179-1181 Sandra Viviana Vergara, Dennis J. Thiele |
| 8. | The Juxtamembrane Region of EGFR Takes Center Stage Pages 1181-1183 Stevan R. Hubbard |
| 9. | Closing in on Mechanisms of Tissue Morphogenesis Pages 1183-1185 Matteo Rauzi, Thomas Lecuit |
| 10. | Fly Stem Cell Research Gets Infectious Pages 1185-1187 Ryan Conder, Juergen A. Knoblich |
| Minireview |
| 11. | Plant Asymmetric Cell Division, Vive la Différence! Pages 1189-1192 Frank L.H. Menke, Ben Scheres |
| Review |
| 12. | CTCF: Master Weaver of the Genome Pages 1194-1211 Jennifer E. Phillips, Victor G. Corces |
| Articles |
| 13. | Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol Pages 1213-1224 Hyock Joo Kwon, Lina Abi-Mosleh, Michael L. Wang, Johann Deisenhofer, Joseph L. Goldstein, Michael S. Brown, Rodney E. Infante |
| 14. | Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation Pages 1225-1234 Qi Wu, Maureen P. Boyle, Richard D. Palmiter |
| 15. | Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism Pages 1235-1246 Jin Nakatani, Kota Tamada, Fumiyuki Hatanaka, Satoko Ise, Hisashi Ohta, Kiyoshi Inoue, Shozo Tomonaga, Yasuhito Watanabe, Yeun Jun Chung, Ruby Banerjee, Kazuya Iwamoto, Tadafumi Kato, Makoto Okazawa, Kenta Yamauchi, Koichi Tanda, Keizo Takao, Tsuyoshi Miyakawa, Allan Bradley, Toru Takumi |
| 16. | Mitochondrial Dysfunction Leads to Nuclear Genome Instability via an Iron-Sulfur Cluster Defect Pages 1247-1258 Joshua R. Veatch, Michael A. McMurray, Zara W. Nelson, Daniel E. Gottschling |
| 17. | Genomic Antagonism between Retinoic Acid and Estrogen Signaling in Breast Cancer Pages 1259-1271 Sujun Hua, Ralf Kittler, Kevin P. White |
| 18. | A Synthetic Genetic Edge Detection Program Pages 1272-1281 Jeffrey J. Tabor, Howard M. Salis, Zachary Booth Simpson, Aaron A. Chevalier, Anselm Levskaya, Edward M. Marcotte, Christopher A. Voigt, Andrew D. Ellington |
| 19. | X-Ray Structures of the Hexameric Building Block of the HIV Capsid Pages 1282-1292 Owen Pornillos, Barbie K. Ganser-Pornillos, Brian N. Kelly, Yuanzi Hua, Frank G. Whitby, C. David Stout, Wesley I. Sundquist, Christopher P. Hill, Mark Yeager |
| 20. | Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment Pages 1293-1307 Natalia Jura, Nicholas F. Endres, Kate Engel, Sebastian Deindl, Rahul Das, Meindert H. Lamers, David E. Wemmer, Xuewu Zhang, John Kuriyan |
| 21. | Exocytosis of Post-Golgi Vesicles Is Regulated by Components of the Endocytic Machinery Pages 1308-1319 Jyoti K. Jaiswal, Victor M. Rivera, Sanford M. Simon |
| 22. | BASL Controls Asymmetric Cell Division in Arabidopsis Pages 1320-1330 Juan Dong, Cora A. MacAlister, Dominique C. Bergmann |
| 23. | Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure Pages 1331-1342 Jerome Solon, Aynur Kaya-Çopur, Julien Colombelli, Damian Brunner |
| 24. | Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut Pages 1343-1355 Huaqi Jiang, Parthive H. Patel, Alexander Kohlmaier, Marc O. Grenley, Donald G. McEwen, Bruce A. Edgar |
| Erratum |
| 25. | Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors Page 1356 Frank Soldner, Dirk Hockemeyer, Caroline Beard, Qing Gao, George W. Bell, Elizabeth G. Cook, Gunnar Hargus, Alexandra Blak, Oliver Cooper, Maisam Mitalipova, Ole Isacson, Rudolf Jaenisch |
| SnapShot |
| 26. | SnapShot: F Box Proteins II Pages 1358.e1-1358.e2 Jeffrey R. Skaar, Vincenzo D'Angiolella, Julia K. Pagan, Michele Pagano |
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