May 2009 Volume 28 Number 18, pp 1941 - 2002
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Nature Insight The Ubiquitin System
This Insight covers the most topical themes in cellular roles of the
ubiquitin system and highlights how an understanding of this system
might contribute to the development of novel therapies.
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ORIGINAL ARTICLES
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NAC-1, a potential stem cell pluripotency factor, contributes to paclitaxel resistance in ovarian cancer through inactivating Gadd45 pathway
N Jinawath, C Vasoontara, K-L Yap, M M Thiaville, K Nakayama, T-L Wang and I-M Shih
Abstract: http://links.ealert.nature.com/ctt?kn=17&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
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DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis
M Olsson, H Vakifahmetoglu, P M Abruzzo, K Hogstrand, A Grandien and B Zhivotovsky
Abstract: http://links.ealert.nature.com/ctt?kn=42&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=18&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
TrkA overexpression enhances growth and metastasis of breast cancer cells
C Lagadec, S Meignan, E Adriaenssens, B Foveau, E Vanhecke, R Romon, R -A Toillon, B Oxombre, H Hondermarck and X Le Bourhis
Abstract: http://links.ealert.nature.com/ctt?kn=10&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
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Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress
T-P Sun and S-Y Shieh
Abstract: http://links.ealert.nature.com/ctt?kn=24&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=41&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
Stanniocalcin-1 acts in a negative feedback loop in the prosurvival ERK1//2 signaling pathway during oxidative stress
A Nguyen, A C M Chang and R R Reddel
Abstract: http://links.ealert.nature.com/ctt?kn=37&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=29&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells
J Zhou, W Huang, R Tao, S Ibaragi, F Lan, Y Ido, X Wu, Y O Alekseyev, M E Lenburg, G-f Hu and Z Luo
Abstract: http://links.ealert.nature.com/ctt?kn=40&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=45&m=32893832&r=MTc2ODI0Mjc1MwS2&b=2&j=NDg1MzUzOTAS1&mt=1&rt=0
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