Learning enhanced by G-CSF

View this message online Hello manoj kumar valluru, G-CSF seems to be getting a lot of attention.  In the previous newsletter we reported a patent, #7,531,510, covering injection of this cytokine for acceleration of post-infarct repair.  This time, we are pleased to report a new paper in which G-CSF administration caused increased spatial learning in rats.  The authors reported a direct anti-apoptotic effect on hippocampal neurons.  Another interesting paper was published last week describing what appears to be transdifferentiation of human cord blood stem cells into hepatocytes in an animal model of liver failure. In terms of patents, #7,531,505 was issued covering a coating for implants that contains an endothelial progenitor cell binding surface, as well as a surface that binds the implant.  This is an interesting way of preventing restenosis.  PPL Therapeutics was granted a patent, #7,531,715, which claims cloning by double nuclear transfer, an interesting variation on a theme.  Also in terms of patents, the question of gene-patenting reared it's head again with the case of Assn for Medical Pathology et al v. USPTO & Myrian & Directors of the University of Utah Research Foundation (SDNY 2009) in which invalidation of IP surrounding the BRCA gene is sought.      Compositions and methods for promoting attachment of cells of endothelial cell lineage to medical devices     Patent Number: 7,531,505 Assignee | Inventor Lack of proper endothelialization of vascular grafts can cause a variety of problems such as restenosis or thrombosis.  The current patent covers a coating for medical devices in which one side of the coating binds to the metallic surface of the device and the other side contains peptides that bind to endothelium or [Read More] Ask a question OR leave your comments.     G-CSF Makes You Smarter Saturday May 16th, 2009 @ 00:59:17 EST Münster, Germany - G-CSF is widely used as a stem cell mobilizer, inducing complement-dependent exit of CD34 and mesenchymal stem cells from the bone marrow.  It has been postulated that G-CSF has not just hematopoietic but also neurogenic activity.  For example, a study reported that [Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News   Media Partnerships (NEW)   PATENTS - WHAT'S GETTING ATTENTION?     Treatment of cancers | 1 Comment(s)     NEWS - WHAT'S GETTING ATTENTION?     Rheumatoid Arthritis Model Treated by Mesenchymal Stem Cells | 2 Comment(s)     Mouse Liver Failure Treated by Human Cord Blood Stem Cells | 1 Comment(s)     Radiation Induced Bacterial Translocation Causes GVHD | 1 Comment(s)     RECENTLY ADDED PATENTS     Methods of recruiting fibroblasts by administering G-CSF (7,531,510) Assignee | Inventor | 1 Comment     Neuronal progenitors from feeder-free human embryonic stem cell culture (7,531,354) Assignee | Inventor | Ask a question OR leave your comments     Compositions and methods for promoting attachment of cells of endothelial cell lineage to medical devices (7,531,505) Assignee | Inventor | Ask a question OR leave your comments     Double nuclear transfer method and results thereof (7,531,715) Assignee | Inventor | Ask a question OR leave your comments     Clusterin-mediated inhibition of apoptosis via stromal bone marrow cell delivery to a cardiac site (7,524,490) Assignee | Inventor | Ask a question OR leave your comments     Method of stimulating stem cells (7,524,500) Assignee | Inventor | Ask a question OR leave your comments     Blood and cell analysis using an imaging flow cytometer (7,522,758) Assignee | Inventor | Ask a question OR leave your comments     Implantable cell/tissue-based biosensing device (7,519,409) Assignee | Inventor | Ask a question OR leave your comments     Method of isolating human neuroepithelial precursor cells from human fetal tissue (7,517,521) Assignee | Inventor | Ask a question OR leave your comments     Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,517,686) Assignee | Inventor | Ask a question OR leave your comments     View all 1418 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     G-CSF Makes You Smarter 3 days ago     Mouse Liver Failure Treated by Human Cord Blood Stem Cells 4 days ago : 1 Comment     Neuroprotective Stem Cell Secreted Peptides May 11th     Allogeneic rejection of embryonic stem cells May 4th     Medistem Fat Stem Cells Help Multiple Sclerosis Patients April 27th     Read more news on StemCellPatents.com     LATEST JOBS POSTS     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com. Media Partnerships (NEW) (BETA) ------------------------------------------------------------ To unsubscribe, click here. Delivered: Tuesday May 19th, 2009 @ 15:10:29 EST