CD163 agonism activates stem cells

View this message online Hello manoj kumar valluru, Last week a patent (#7,524,500) was issued covering the crosslinking of CD163 as a method of activating stem cells.  CD163 is a scavenger receptor primarily known for its expression on macrophages. Another relevant patent from last week was #7,524,490 which covers the use of clusterin transfected bone marrow stem cells for suppressing apoptosis in the heart.  Clusterin is a protein involved in control of cell death and cell communications.  In the news, a paper was published describing rejection of allogeneic embryonic stem cell derived dopaminergic cells in an allogeneic system.   Method of stimulating stem cells     Patent Number: 7,524,500 Assignee | Inventor Methods of expanding stem cells are well-known in the art.  For example, #7,423,029 teaches the use of heterocyclic trialkyl ammonium-containing compounds for stimulation of bone marrow stem cells.  #7,135,459 covers use of FGF homologues for expansion of neural and...[Read More] Ask a question OR leave your comments.     Allogeneic rejection of embryonic stem cells Monday May 4th, 2009 @ 02:15:43 EST Nara, Japan - Seeing stem cell therapy as sources of cytokines or angiogenic factors allows the possibility that the stem cell will eventually be rejected but the therapeutic effect will remain.  For example, mesenchymal stem cells are known to secrete various immune modulatory factors, such as soluble [Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News   Media Partnerships (NEW)   RECENTLY ADDED PATENTS     Clusterin-mediated inhibition of apoptosis via stromal bone marrow cell delivery to a cardiac site (7,524,490) Assignee | Inventor | Ask a question OR leave your comments     Method of stimulating stem cells (7,524,500) Assignee | Inventor | Ask a question OR leave your comments     Blood and cell analysis using an imaging flow cytometer (7,522,758) Assignee | Inventor | Ask a question OR leave your comments     Implantable cell/tissue-based biosensing device (7,519,409) Assignee | Inventor | Ask a question OR leave your comments     Method of isolating human neuroepithelial precursor cells from human fetal tissue (7,517,521) Assignee | Inventor | Ask a question OR leave your comments     Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,517,686) Assignee | Inventor | Ask a question OR leave your comments     Cardiac muscle regeneration using mesenchymal stem cells (7,514,074) Assignee | Inventor | Ask a question OR leave your comments     Feeder independent extended culture of embryonic stem cells (7,514,260) Assignee | Inventor | Ask a question OR leave your comments     Platelet-derived growth factor protection of cardiac myocardium (7,514,261) Assignee | Inventor | Ask a question OR leave your comments     Isolation and transplantation of retinal stem cells (7,514,259) Assignee | Inventor | Ask a question OR leave your comments     View all 1414 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     Allogeneic rejection of embryonic stem cells 1 day ago     Medistem Fat Stem Cells Help Multiple Sclerosis Patients April 27th     Low Oxygen Tension for Cancer Stem Cells: Keeping it Real April 20th     Stem cells improve post-infarct heart function April 14th : 1 Comment     Novocell Awarded Seminal Stem Cell Patent April 6th     Read more news on StemCellPatents.com     LATEST JOBS POSTS     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com. Media Partnerships (NEW) (BETA) ------------------------------------------------------------ To unsubscribe, click here. Delivered: Tuesday May 5th, 2009 @ 15:10:24 EST