April 2009 Volume 28 Number 14, pp 1653 - 1735
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Nature Insight The Ubiquitin System (Itls/bold)
This Insight covers the most topical themes in cellular roles of the
ubiquitin system and highlights how an understanding of this system
might contribute to the development of novel therapies.
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Produced with support from
Hybrigenics, ITI Life Sciences and Scil Proteins GmbH
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Call for papers!
Submit your best work in the field oncogenes, including mechanism of
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REVIEW
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The SWI//SNF complex and cancer
D Reisman, S Glaros and E A Thompson
Abstract: http://links.ealert.nature.com/ctt?kn=16&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=37&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
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ORIGINAL ARTICLES
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Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients
A K Samanta, S N Chakraborty, Y Wang, H Kantarjian, X Sun, J Hood, D Perrotti and R B Arlinghaus
Abstract: http://links.ealert.nature.com/ctt?kn=35&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=40&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells
G Tilman, A Loriot, A Van Beneden, N Arnoult, J A Londono-Vallejo, C De Smet and A Decottignies
Abstract: http://links.ealert.nature.com/ctt?kn=18&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=4&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
VHL Type 2B gene mutation moderates HIF dosage in vitro and in vivo
C M Lee, M M Hickey, C A Sanford, C G McGuire, C L Cowey, M C Simon and W K Rathmell
Abstract: http://links.ealert.nature.com/ctt?kn=7&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=10&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells
B P Fox and R P Kandpal
Abstract: http://links.ealert.nature.com/ctt?kn=17&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=38&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
miR-449a targets HDAC-1 and induces growth arrest in prostate cancer
E J Noonan, R F Place, D Pookot, S Basak, J M Whitson, H Hirata, C Giardina and R Dahiya
Abstract: http://links.ealert.nature.com/ctt?kn=12&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=42&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Phosphorylated ezrin is associated with EBV latent membrane protein 1 in nasopharyngeal carcinoma and induces cell migration
K Endo, S Kondo, J Shackleford, T Horikawa, N Kitagawa, T Yoshizaki, M Furukawa, Y Zen and J S Pagano
Abstract: http://links.ealert.nature.com/ctt?kn=34&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=28&m=32257256&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcyNDAyNDYS1&mt=1&rt=0
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