April 2009 Volume 28 Number 13, pp 1569 - 1651
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Nature Insight The Ubiquitin System
This Insight covers the most topical themes in cellular roles of the
ubiquitin system and highlights how an understanding of this system
might contribute to the development of novel therapies.
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Produced with support from
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EDITORIAL
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April Fish
D R Green
http://links.ealert.nature.com/ctt?kn=38&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
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ORIGINAL ARTICLES
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Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates
D Yamazaki, S Kurisu and T Takenawa
Abstract: http://links.ealert.nature.com/ctt?kn=37&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
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TRAF2-binding BIR1 domain of c-IAP2//MALT1 fusion protein is essential for activation of NF-[kappa]B
J B Garrison, T Samuel and J C Reed
Abstract: http://links.ealert.nature.com/ctt?kn=19&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=4&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
The role of the Birt-Hogg-Dube protein in mTOR activation and renal tumorigenesis
T R Hartman, E Nicolas, A Klein-Szanto, T Al-Saleem, T P Cash, M C Simon and E P Henske
Abstract: http://links.ealert.nature.com/ctt?kn=7&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=10&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression
W D Thomas, J Chen, Y R Gao, B Cheung, J Koach, E Sekyere, M D Norris, M Haber, T Ellis, B Wainwright and G M Marshall
Abstract: http://links.ealert.nature.com/ctt?kn=17&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=39&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway
C S Busso, T Iwakuma and T Izumi
Abstract: http://links.ealert.nature.com/ctt?kn=12&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=43&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-[kappa]B2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes
I Robert, M Aussems, A Keutgens, X Zhang, B Hennuy, P Viatour, G Vanstraelen, M-P Merville, J-P Chapelle, L de Leval, F Lambert, E Dejardin, A Gothot and A Chariot
Abstract: http://links.ealert.nature.com/ctt?kn=35&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=29&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Cooperation between GLI and JUN enhances transcription of JUN and selected GLI target genes
S Laner-Plamberger, A Kaser, M Paulischta, C Hauser-Kronberger, T Eichberger and A M Frischauf
Abstract: http://links.ealert.nature.com/ctt?kn=52&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=49&m=32244768&r=MTc2ODI0Mjc1MwS2&b=2&j=NDcwNzQ4NTAS1&mt=1&rt=0
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