April 2009 Volume 5 Number 4
Visit Nature Reviews Neurology online to browse the journal.
Now available at
http://links.ealert.nature.com/ctt?kn=81&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Please note that you need to be a subscriber to enjoy full text access
to Nature Reviews Neurology online. To purchase a subscription, please
visit:
http://links.ealert.nature.com/ctt?kn=43&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Alternatively, to recommend a subscription to your library, please visit
http://links.ealert.nature.com/ctt?kn=65&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
*********************************************************************
Nature Reviews Neurology Impact Factor: 4.339*
(*Journal Citation Reports, Thomson, 2005)
*********************************************************************
=========================== ADVERTISEMENT ===========================
Nature Clinical Practice Neurology is now Nature Reviews Neurology.
Nature Reviews Neurology brings the distinguished reputation of the
Nature Reviews series into the clinical sciences. The journal will
remain dedicated to publishing the latest clinical advances in neurology.
For more information visit
http://links.ealert.nature.com/ctt?kn=12&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
=====================================================================
----------------------
RESEARCH HIGHLIGHTS
----------------------
Multiple sclerosis: Stem cell transplants ameliorate neurological deficits
in multiple sclerosis
p175 | doi:10.1038/nrneurol.2009.14
http://links.ealert.nature.com/ctt?kn=2&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Neuroendocrinology: Metabolic syndrome in depression is linked to TPH2
p176 | doi:10.1038/nrneurol.2009.15
http://links.ealert.nature.com/ctt?kn=78&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
IN BRIEF
Stroke | Epilepsy | Neuromuscular disease | Pain
p176 | doi:10.1038/nrneurol.2009.34
http://links.ealert.nature.com/ctt?kn=7&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Pain: Relief of pain in Parkinson disease
p177 | doi:10.1038/nrneurol.2009.19
http://links.ealert.nature.com/ctt?kn=75&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Peripheral neuropathies: Oxycodone treatment for pain in herpes zoster
p177 | doi:10.1038/nrneurol.2009.20
http://links.ealert.nature.com/ctt?kn=84&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Similarities in seizure disorders
p177 | doi:10.1038/nrneurol.2009.21
http://links.ealert.nature.com/ctt?kn=24&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Parkinson disease: Accurate noninvasive diagnosis of Parkinson disease
p178 | doi:10.1038/nrneurol.2009.16
http://links.ealert.nature.com/ctt?kn=14&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Movement disorders: A nondopaminergic treatment for RLS
p178 | doi:10.1038/nrneurol.2009.18
http://links.ealert.nature.com/ctt?kn=54&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Neurodegenerative disease: DCTN1 mutations are associated with Perry
syndrome
p179 | doi:10.1038/nrneurol.2009.27
http://links.ealert.nature.com/ctt?kn=64&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
IN BRIEF
Intracerebral hemorrhage | Cerebrovascular disease | Alzheimer disease |
Neural repair and rehabilitation
p179 | doi:10.1038/nrneurol.2009.33
http://links.ealert.nature.com/ctt?kn=30&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Cerebrovascular malformations: Understanding CCMs
p180 | doi:10.1038/nrneurol.2009.13
http://links.ealert.nature.com/ctt?kn=89&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Modeling pathology with IPS cells
p180 | doi:10.1038/nrneurol.2009.17
http://links.ealert.nature.com/ctt?kn=92&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
----------------------
NEWS AND VIEWS
----------------------
Stroke: Risks of microcatheter injections in acute stroke treatment
Rishi Gupta
p181 | doi:10.1038/nrneurol.2009.29
The use of repeated microcatheter injections during intra-arterial
procedures to treat acute stroke is associated with an increased risk
of intracranial hemorrhage. The number of such injections performed
should, therefore, be minimized.
http://links.ealert.nature.com/ctt?kn=68&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Multiple sclerosis: MRI-the perfect surrogate marker for multiple
sclerosis?
Frederik Barkhof and Massimo Filippi
p182 | doi:10.1038/nrneurol.2009.31
MRI provides a very sensitive reflection of the histopathological changes
in multiple sclerosis. Many short-term studies fail to appreciate the
relationship between MRI and clinical findings, although such shortcomings
might be argued to reflect a weakness of clinical measures, rather than
of MRI.
http://links.ealert.nature.com/ctt?kn=86&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Health disparities research: Disparities research in neurology: an urgent
need
Barbara G. Vickrey and Martin F. Shapiro
p184 | doi:10.1038/nrneurol.2009.30
Differences in the frequencies of physician and emergency-room visits
and hospitalizations across socioeconomic and ethnic groups may lead
to poor health outcomes in disadvantaged populations. Analyzing the
causes and implementing interventions to redress such disparities is a
high priority in the US, but neurology lags behind other clinical
specialties in this research.
http://links.ealert.nature.com/ctt?kn=42&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Prion diseases: Movement disorders reveal Creutzfeldt-Jakob disease
Michael Weller and Adriano Aguzzi
p185 | doi:10.1038/nrneurol.2009.32
Human prion diseases are sometimes difficult to diagnose because few
clinical features distinguish them reliably from other neurological
disorders. A new study suggests that analysis of movement disorders
might contribute to the clinical differentiation of sporadic
Creutzfeldt-Jakob disease from Alzheimer disease and dementia with
Lewy bodies.
http://links.ealert.nature.com/ctt?kn=23&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Multiple sclerosis: Sorting through the pediatric MS spectrum with
brain MRI
Dorothee Chabas and Daniel Pelletier
p186 | doi:10.1038/nrneurol.2009.35
Distinguishing between a first episode of multiple sclerosis and acute
disseminated encephalomyelitis in children who present with an initial
demyelinating event can be a clinical challenge. New brain MRI criteria
that aim to differentiate these clinical presentations, and revised
McDonald MRI criteria specific for the pediatric population, are both
worthy of note.
http://links.ealert.nature.com/ctt?kn=49&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
----------------------
REVIEWS
----------------------
Diagnosis and management of the neurological complications of falciparum
malaria
Saroj K. Mishra and Charles R. J. C. Newton
p189 | doi:10.1038/nrneurol.2009.23
Malaria is a serious public health problem in the developing world, and
is also being seen increasingly in Western countries as a result of travel
and immigration. Malaria is associated with a number of neurological
complications, including agitation, psychosis, seizures, impaired
consciousness and coma. In this article, Mishra and Newton describe these
complications, discuss the underlying pathogenesis, and outline current
and future management strategies.
Abstract: http://links.ealert.nature.com/ctt?kn=13&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=55&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
New insights into headache: an update on functional and structural imaging
findings
Arne May
p199 | doi:10.1038/nrneurol.2009.28
The application of neuroimaging to headache has greatly enhanced our
understanding of the pathophysiology of this syndrome. Here, Arne May
describes neuroimaging as a diagnostic tool for headache and highlights
the advances made with functional and structural neuroimaging in the
study of primary headache syndromes such as migraine and trigeminal
autonomic headaches.
Abstract: http://links.ealert.nature.com/ctt?kn=93&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=52&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Delirium in elderly adults: diagnosis, prevention and treatment
Tamara G. Fong, Samir R. Tulebaev and Sharon K. Inouye
p210 | doi:10.1038/nrneurol.2009.24
Delirium is an acute neuropsychiatric syndrome, the core features of
which are inattention and global cognitive dysfunction. Fong and Inouye
review current clinical practice in delirium in elderly individuals,
including diagnosis, treatment and outcomes. They also consider the
profound impact of this syndrome on health-care utilization and costs.
Abstract: http://links.ealert.nature.com/ctt?kn=41&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=91&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Diagnosis and treatment of Friedreich ataxia: a European perspective
Jorg B. Schulz, Sylvia Boesch, Katrin Burk, Alexandra Durr, Paola Giunti,
Caterina Mariotti, Francoise Pousset, Ludger Schols, Pierre Vankan and
Massimo Pandolfo
p222 | doi:10.1038/nrneurol.2009.26
Friedreich ataxia (FRDA) is the most common of the inherited ataxias,
with an estimated prevalence of 3-4 cases per 100,000 individuals.
There are, as yet, no robust evidence-based standards of care for FRDA.
This Review article pools the expertise of FRDA specialists across
Western Europe to formulate a set of guidelines for the diagnosis and
treatment of this debilitating condition.
Abstract: http://links.ealert.nature.com/ctt?kn=69&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=70&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
=========================== ADVERTISEMENT ===========================
Journal of Perinatology continues to impact the work of researchers and
the lives of neonates for nearly 30 years.
Journal of Perinatology delivers original articles, clinical reviews,
and research reports on the latest findings in neonatology, covering:
- Maternal and fetal medicine
- The neonatal period
- The follow-up of the infant and child
Visit http://links.ealert.nature.com/ctt?kn=57&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
to view the latest research and gain open access to timely and popular
articles throughout the year.
=====================================================================
You have been sent this Table of Contents Alert because you have opted
in to receive it. You can change or discontinue your e-mail alerts at
any time, by modifying your preferences on your nature.com account at:
http://links.ealert.nature.com/ctt?kn=28&m=32249752&r=MTc2NDUyMzIwMwS2&b=2&j=NDcxNDY4NzgS1&mt=1&rt=0
(You will need to log in to be recognised as a nature.com registrant).
For further technical assistance, please contact our registration department:
registration@nature.com
For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com
For other enquiries, please contact our customer feedback department:
feedback@nature.com
Nature Publishing Group | 75 Varick Street, 9th Floor | New York |
NY 10013-1917 | USA
Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne -
San Diego - San Francisco - Washington - New York - Boston
(c) Copyright 2009 Nature Publishing Group
=====================================================================
