April 2009 Volume 10 Number 4, pp 293-413
(c) Copyright 2009 by the European Molecular Biology Organization
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Contents: Volume 10, Number 4 (April 2009)
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EDITORIALS
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Goodbye.
Frank Gannon
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Change.
Hermann Bujard
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Many pies, one finger.
Howy Jacobs
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SCIENCE AND SOCIETY
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CORRESPONDENCE
Comment on `When in Rome, reform'.
Maurizio Bifulco & Antonietta Santoro
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OPINIONS
Darwin, race and gender.
Steven Rose
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The greatest book you never read.
Gregory A Petsko
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TALKING POINTS
Morality and human embryo research. Introduction to the Talking Point on morality and human embryo research.
Thomas Baldwin
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Embryonic human persons. Talking Point on morality and human embryo research.
Robert P George & Patrick Lee
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Destroying unwanted embryos in research. Talking Point on morality and human embryo research.
Thomas Douglas & Julian Savulescu
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VIEWPOINTS
Societal dialogue needs more than public engagement. Science & Society Series on Convergence Research.
Maud Radstake, Eefje van den Heuvel-Vromans, Ninne Jeucken, Koen Dortmans & Annemiek Nelis
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A forum for `doing society and genomics'. Science & Society Series on Convergence Research.
Emma K Frow
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ANALYSIS
All in the mind? New molecular insights might bridge the gap between the effects of psychiatric therapy and drugs.
Philip Hunter
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REVIEWS
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MEETING REPORTS
How are neurons wired to form functional and plastic circuits? Meeting on Axon Guidance, Synaptogenesis & Neural Plasticity.
Esther Stoeckli & Yimin Zou
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Change we can believe in[mdash]of the conformational type. Workshop on the Initiation of Antigen Receptor Signaling.
Pavel Tolar & Susan K Pierce
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The quest for a better resolution of protein-translocation processes. Conference on the Control, Co-ordination and Regulation of Protein Targeting and Translocation.
Nica Borgese, Arnold J. M. Driessen, Doron Rapaport & Colin Robinson
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In the land of the rising sun with the COP9 signalosome and related Zomes. Symposium on the COP9 signalosome, Proteasome and eIF3.
Elah Pick & Lionel Pintard
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LITERATURE REPORT
Filamin B: a scaffold for interferon signalling.
Alan J Whitmarsh
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CONCEPT
Revisiting the COP9 signalosome as a transcriptional regulator.
Daniel A Chamovitz
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REVIEW
From cancer genomes to cancer models: bridging the gaps.
Anais Baudot, Francisco X. Real, José M. G. Izarzugaza & Alfonso Valencia
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SCIENTIFIC REPORTS
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Activation of RXR[ndash]PPAR heterodimers by organotin environmental endocrine disruptors.
Albane le Maire, Marina Grimaldi, Dominique Roecklin, Sonia Dagnino, Valérie Vivat-Hannah, Patrick Balaguer & William Bourguet
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ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway.
Young Joo Jeon, Joon Seok Choi, Jung Yun Lee, Kyung Ryun Yu, Sangman Michael Kim, Seung Hyeun Ka, Kyu Hee Oh, Keun Il Kim, Dong-Er Zhang, Ok Sun Bang & Chin Ha Chung
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Phosphorylation of NF-[kappa]B p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination.
Hui Geng, Tobias Wittwer, Oliver Dittrich-Breiholz, Michael Kracht & Michael Lienhard Schmitz
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Midzone organization restricts interpolar microtubule plus-end dynamics during spindle elongation.
Vladimir Fridman, Adina Gerson-Gurwitz, Natalia Movshovich, Martin Kupiec & Larisa Gheber
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http://links.ealert.nature.com/ctt?kn=7&m=32242203&r=MTc2MDI0MTQ4MQS2&b=2&j=NDcwNTE0NjAS1&mt=1&rt=0
Fork regression is an active helicase-driven pathway in bacteriophage T4.
David T Long & Kenneth N Kreuzer
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miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis.
Christoph A Gebeshuber, Kurt Zatloukal & Javier Martinez
http://links.ealert.nature.com/ctt?kn=29&m=32242203&r=MTc2MDI0MTQ4MQS2&b=2&j=NDcwNTE0NjAS1&mt=1&rt=0
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A model for DNA replication showing how dormant origins safeguard against replication fork failure.
J Julian Blow & Xin Quan Ge
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CORRIGENDUM
Crystal structure of CbpF, a bifunctional choline-binding protein and autolysis regulator from Streptococcus pneumoniae.
Rafael Molina, Ana González, Meike Stelter, Inmaculada Pérez-Dorado, Richard Kahn, María Morales, Miriam Moscoso, Susana Campuzano, Nuria E Campillo, Shahriar Mobashery, José L García, Pedro García & Juan A Hermoso
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