May 2009 Volume 16 Number 5, pp 383 - 472
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Nature Collections Cancer
This week, Nature updates the Nature Collection on Cancer with a
series of research papers and review material on some of the recent
advances in cancer research.
Access selected content from the updated collection free online for
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Nature Collections Cancer is produced with support from Cephalon,
Genentech,
Boehringer Ingelheim and Asterand
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Advance Online Publication
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Articles for this journal are published online ahead of print through
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ORIGINAL ARTICLES
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Combination therapy with radiation or cisplatin enhances the potency
of Ad5/35 chimeric oncolytic adenovirus in a preclinical model of head
and neck cancer
S Ganesh, M Gonzalez-Edick, D Gibbons, Y Ge, M VanRoey, M Robinson and
K Jooss
Abstract: http://links.ealert.nature.com/ctt?kn=30&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=37&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Potentiation of methoxymorpholinyl doxorubicin antitumor activity by
P450 3A4 gene transfer
H Lu, C-S Chen and D J Waxman
Abstract: http://links.ealert.nature.com/ctt?kn=22&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=19&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Drug-virus interaction: effect of administration of recombinant
adenoviruses on the pharmacokinetics of docetaxel in a rat model
P Wonganan, W C Zamboni, S Strychor, J D Dekker and M A Croyle
Abstract: http://links.ealert.nature.com/ctt?kn=28&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=26&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Tetracycline-inducible promoter-based conditionally replicative
adenoviruses for the control of viral replication
H Zhang, K Takayama, L Zhang, J Uchino, A Harada, T Harada, J Hisasue,
N Nakagaki, C Zhou and Y Nakanishi
Abstract: http://links.ealert.nature.com/ctt?kn=3&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=18&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Nanoparticle delivery of anti-metastatic NM23-H1 gene improves chemotherapy
in a mouse tumor model
Z Li, J Xiang, W Zhang, S Fan, M Wu, X Li and G Li
Abstract: http://links.ealert.nature.com/ctt?kn=17&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=15&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Transgene expression of [alpha] tumor necrosis factor with mutations
D142N and A144R under control of human telomerase reverse transcriptase
promoter eradicates well-established tumors and induces long-term antitumor
immunity
J Xiang, M A Munegowda and Y Deng
Abstract: http://links.ealert.nature.com/ctt?kn=9&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=47&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Retrovirally transduced murine T lymphocytes expressing FasL mediate
effective killing of prostate cancer cells
J C Symes, C Siatskas, D H Fowler and J A Medin
Abstract: http://links.ealert.nature.com/ctt?kn=27&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=12&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral
oncolysis of hepatocellular carcinoma cells
E-H Park, S S Koh, R Srisuttee, I-R Cho, H-J Min, B H Jhun, Y-S Lee,
K L Jang, C-H Kim, R N Johnston and Y-H Chung
Abstract: http://links.ealert.nature.com/ctt?kn=43&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=20&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
An oral TLR7 agonist is a potent adjuvant of DNA vaccination in transgenic
mouse tumor models
S Dharmapuri, L Aurisicchio, P Neuner, M Verdirame, G Ciliberto and
N La Monica
Abstract: http://links.ealert.nature.com/ctt?kn=51&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=52&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
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Special Issue on Gene Therapy for Chronic Pain
Guest Editors: Joseph Glorioso and David Fink
Volume 16 Number 4
Chronic pain is a significant medical problem. Recent studies suggest
that employing gene transfer to release neuroactive peptides at
targeted sites in the pain pathway may be an effective means to reduce
pain, while avoiding off-target side effects that limit pharmacologic
treatment. This issue surveys results from preclinical animal studies
using several different vector technologies, and describes the first
clinical trial of gene transfer for the treatment of pain using an
HSV-based vector that began enrolling patients in December 2008.
Free content available now
http://links.ealert.nature.com/ctt?kn=36&m=32270658&r=MTc3MTg1MDcyMQS2&b=2&j=NDc0MDQyNDQS1&mt=1&rt=0
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