Volume 100 Number 5
Published online 3 March 2009 (671 - 864)
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British Journal of Cancer publishes high quality original papers
and reviews that make a significant contribution to increasing
understanding of the causes of cancer and to improving the treatment
and survival of patients.
Visit the journal online at
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British Journal of Cancer has an impact factor 4.635*
*2007 Journal Citation Report (Thomson Reuters, 2008)
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REVIEW
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CYP17 blockade by abiraterone: further evidence for frequent
continued hormone-dependence in castration-resistant prostate cancer
J E Ang, D Olmos and J S de Bono
Abstract: http://links.ealert.nature.com/ctt?kn=102&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=45&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
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CLINICAL STUDIES
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The expression of RUNX3 in colorectal cancer is associated with
disease stage and patient outcome
R Soong, N Shah, B K Peh, P Y Chong, S S Ng, N Zeps, D Joseph,
M Salto-Tellez, B Iacopetta and Y Ito
Abstract: http://links.ealert.nature.com/ctt?kn=82&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=32&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Poor survival outcomes in HER2-positive breast cancer patients with
low-grade, node-negative tumours
S M Tovey, S Brown, J C Doughty, E A Mallon, T G Cooke and J Edwards
Abstract: http://links.ealert.nature.com/ctt?kn=98&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=80&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Management of cardiac health in trastuzumab-treated patients with
breast cancer: updated United Kingdom National Cancer Research
Institute recommendations for monitoring
A L Jones, M Barlow, P J Barrett-Lee, P A Canney, I M Gilmour,
S D Robb, C J Plummer, A M Wardley and M W Verrill
Abstract: http://links.ealert.nature.com/ctt?kn=61&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=106&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
The impact of 18-fluorodeoxyglucose positron emission tomography
on the staging, management and outcome of anal cancer
E de Winton, A G Heriot, M Ng, R J Hicks, A Hogg, A Milner,
T Leong, M Fay, J MacKay, E Drummond and S Y Ngan
Abstract: http://links.ealert.nature.com/ctt?kn=44&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=14&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Comparison of tumour-based (Petersen Index) and inflammation-based
(Glasgow Prognostic Score) scoring systems in patients
undergoing curative resection for colon cancer
C S D Roxburgh, J E M Crozier, F Maxwell, A K Foulis, J Brown,
R F McKee, J H Anderson, P G Horgan and D C McMillan
Abstract: http://links.ealert.nature.com/ctt?kn=2&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=72&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Extended weekly dose-dense paclitaxel//carboplatin is feasible and
active in heavily pre-treated platinum-resistant recurrent ovarian
cancer
R Sharma, J Graham, H Mitchell, A Brooks, S Blagden and H Gabra
Abstract: http://links.ealert.nature.com/ctt?kn=19&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=157&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
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TRANSLATIONAL THERAPEUTICS
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Dietary supplementation with a specific combination of high protein,
leucine, and fish oil improves muscle function and daily activity
in tumour-bearing cachectic mice
K van Norren, D Kegler, J M Argiles, Y Luiking, M Gorselink, A Laviano,
K Arts, J Faber, H Jansen, E M van der Beek and A van Helvoort
Abstract: http://links.ealert.nature.com/ctt?kn=141&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=46&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide
derivatives and the effect of RNA silencing on intracellular metabolism
L Bourre, F Giuntini, I M Eggleston, M Wilson and A J MacRobert
Abstract: http://links.ealert.nature.com/ctt?kn=130&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=100&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Biomarker analysis in stage III-IV (M0) gastric cancer patients who
received curative surgery followed by adjuvant 5-fluorouracil and
cisplatin chemotherapy: epidermal growth factor receptor (EGFR)
associated with favourable survival
J-S Kim, M-A Kim, T M Kim, S-H Lee, D-W Kim, S-A Im, T-Y Kim, W H Kim,
H-K Yang, D S Heo, Y-J Bang, K-U Lee, K-J Choe and N K Kim
Abstract: http://links.ealert.nature.com/ctt?kn=41&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=115&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Apollon gene silencing induces apoptosis in breast cancer cells
through p53 stabilisation and caspase-3 activation
A Lopergolo, M Pennati, P Gandellini, N I Orlotti, P Poma, M G Daidone,
M Folini and N Zaffaroni
Abstract: http://links.ealert.nature.com/ctt?kn=101&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=26&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Treatment regimen determines whether an HIF-1 inhibitor enhances or
inhibits the effect of radiation therapy
H Harada, S Itasaka, Y Zhu, L Zeng, X Xie, A Morinibu, K Shinomiya and
M Hiraoka
Abstract: http://links.ealert.nature.com/ctt?kn=97&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=138&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Combined inhibition of DNA methylation and histone acetylation enhances
gene re-expression and drug sensitivity in vivo
N Steele, P Finn, R Brown and J A Plumb
Abstract: http://links.ealert.nature.com/ctt?kn=110&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=123&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
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MOLECULAR DIAGNOSTICS
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Overexpression of E2F-5 correlates with a pathological basal phenotype
and a worse clinical outcome
S Umemura, M Shirane, S Takekoshi, T Kusakabe, J Itoh, N Egashira,
Y Tokuda, K Mori and Y R Osamura
Abstract: http://links.ealert.nature.com/ctt?kn=143&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=147&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
HIF-1[alpha] determines the metastatic potential of gastric cancer cells
N Rohwer, S Lobitz, K Daskalow, T Jons, M Vieth, P M Schlag, W Kemmner,
B Wiedenmann, T Cramer and M Hocker
Abstract: http://links.ealert.nature.com/ctt?kn=150&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=77&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Relation between outcomes and localisation of p-mTOR expression in
gastric cancer
T Murayama, M Inokuchi, Y Takagi, H Yamada, K Kojima, J Kumagai,
T Kawano and K Sugihara
Abstract: http://links.ealert.nature.com/ctt?kn=40&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=55&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Taurine: a potential marker of apoptosis in gliomas
K S Opstad, B A Bell, J R Griffiths and F A Howe
Abstract: http://links.ealert.nature.com/ctt?kn=85&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=12&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
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EPIDEMIOLOGY
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Does type 2 diabetes influence the risk of oesophageal adenocarcinoma?
R E Neale, J D Doecke, N Pandeya, S Sadhegi, A C Green, P M Webb and D C Whiteman
Abstract: http://links.ealert.nature.com/ctt?kn=74&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=58&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Trends in the incidence of primary liver cancer in Central Uganda,
1960-1980 and 1991-2005
P Ocama, S Nambooze, C K Opio, M S Shiels, H R Wabinga and G D Kirk
Abstract: http://links.ealert.nature.com/ctt?kn=16&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=28&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Birth characteristics and risk of colorectal cancer: a study among
Swedish twins
S Cnattingius, F Lundberg and A Iliadou
Abstract: http://links.ealert.nature.com/ctt?kn=42&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=81&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Is the biology of breast cancer changing? A study of hormone receptor
status 1984-1986 and 1996-1997
S B F Brown, E A Mallon, J Edwards, F M Campbell, L M McGlynn,
B Elsberger and T G Cooke
Abstract: http://links.ealert.nature.com/ctt?kn=104&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=30&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Radiation to supraclavicular and internal mammary lymph nodes in breast
cancer increases the risk of stroke
G Nilsson, L Holmberg, H Garmo, A Terent and C Blomqvist
Abstract: http://links.ealert.nature.com/ctt?kn=146&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=59&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Breast cancer risk in elderly women with systemic autoimmune rheumatic
diseases: a population-based case-control study
S M Gadalla, S Amr, P Langenberg, M Baumgarten, W F Davidson,
C Schairer, E A Engels, R M Pfeiffer and J J Goedert
Abstract: http://links.ealert.nature.com/ctt?kn=124&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=155&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Risks of myeloid malignancies in patients with autoimmune conditions
L A Anderson, R M Pfeiffer, O Landgren, S Gadalla, S I Berndt
and E A Engels
Abstract: http://links.ealert.nature.com/ctt?kn=18&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=108&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Cancer risk in hospitalised asthma patients
J Ji, X Shu, X Li, K Sundquist, J Sundquist and K Hemminki
Abstract: http://links.ealert.nature.com/ctt?kn=39&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=136&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Urinary tract infections and reduced risk of bladder cancer in
Los Angeles
X Jiang, J E Castelao, S Groshen, V K Cortessis, D Shibata,
D V Conti, J-M Yuan, M C Pike and M Gago-Dominguez
Abstract: http://links.ealert.nature.com/ctt?kn=145&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=23&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Pattern of cancer risk in persons with AIDS in Italy in the HAART era
L Dal Maso, J Polesel, D Serraino, M Lise, P Piselli, F Falcini, A Russo,
T Intrieri, M Vercelli, P Zambon, G Tagliabue, R Zanetti, M Federico,
R M Limina, L Mangone, V De Lisi, F Stracci, S Ferretti, S Piffer,
M Budroni, A Donato, A Giacomin, F Bellu, M Fusco, A Madeddu,
S Vitarelli, R Tessandori, R Tumino, B Suligoi and S Franceschi
Abstract: http://links.ealert.nature.com/ctt?kn=134&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=34&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Tobacco chewing and female oral cavity cancer risk in Karunagappally
cohort, India
P A Jayalekshmi, P Gangadharan, S Akiba, R R K Nair, M Tsuji
and B Rajan
Abstract: http://links.ealert.nature.com/ctt?kn=91&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=86&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Unchanged incidence and increased survival in children with
neuroblastoma in Denmark 1981-2000: a population-based study
H Schroeder, J Wacher, H Larsson, S Rosthoej, C Rechnitzer, B L Pedersen
and N L T Carlsen
Abstract: http://links.ealert.nature.com/ctt?kn=156&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=38&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Cancer survival discrepancies in developed and developing countries:
comparisons between the Philippines and the United States
M T Redaniel, A Laudico, M R Mirasol-Lumague, A Gondos, D Pulte,
C Mapua and H Brenner
Abstract: http://links.ealert.nature.com/ctt?kn=5&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=3&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
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LETTER TO THE EDITOR
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Infections in early life and risk of childhood ALL
M Greaves and P A Buffler
http://links.ealert.nature.com/ctt?kn=57&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
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BOOK REVIEW
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Apoptosis, senescence and cancer (cancer drug discovery and development)
A Young
http://links.ealert.nature.com/ctt?kn=129&m=31807394&r=MTc2MDAwMTgxNgS2&b=2&j=NDYyNjczMDMS1&mt=1&rt=0
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