Nanocircles for Life Extension

View this message online Hello manoj kumar valluru, Last week an interesting patent was issued, #7,482,332, covering a type of nano-circle DNA construct that may be administered to cells to prevent telomere shortening and presumably senescence.  The inventors are proposing this to be an alternative to having to physicially transfect with the hTERT gene.  Other patents issued last week include #7,482,025, which covers methods of using decellularized liver for assisting tissue regrowth, as well as # 7,483,749 covering use of electrical pulses to stimulate cardiac regeneration. In the news, our friends who are dentists will enjoy hearing that periodontal ligament derived mesenchymal stem cells, as well as gingival fibroblasts, have immune modulatory activities similar to bone marrow mesenchymal stem cells, mediated through TGF-beta, HGF, and induction of IDO activity. Additionally, for those of you who missed the announcement we made earlier in the week, the company International Stem Cell (ISCO) is making progress in using parthenogenic derived stem cells for growing of corneal tissue.  As a last note, we would like to wish a very happy birthday to Eli Sercarz, one of the most inspiring immunologists and human beings.   Telomere-encoding synthetic DNA nanocircles, and their use for the elongation of telomere repeats     Patent Number: 7,482,332 Assignee | Inventor Telomeres are repeats of the TTAGGG sequence on the ends of chromosomes that progressively get shorter with each cell division, causing eventual cell senescence.  The enzyme telomerase is important in cells that need to proliferate longer, for example memory T cells, or stem cells.  It is a dream of many to...[Read More] Ask a question OR leave your comments.       Periodontal Ligament Mesenchymals are Immune Suppressive Sunday February 1st, 2009 @ 17:42:33 EST Mesenchymal stem cells, or cells resembling these cells, have been found in a variety of different tissues in addition to the bone marrow.  These include, fat, menstrual blood and teeth.  One interesting question is how these cells differ from each...[Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News     The Stem Cell Meeting (March 2009) Media Partnerships (NEW)   NEWS - WHAT'S GETTING ATTENTION?     Bone Marrow Stem Cells for Renal Failure | 5 Comment(s)     RECENTLY ADDED PATENTS     Biomaterial derived from vertebrate liver tissue (7,482,025) Assignee | Inventor | Ask a question OR leave your comments     Telomere-encoding synthetic DNA nanocircles, and their use for the elongation of telomere repeats (7,482,332) Assignee | Inventor | Ask a question OR leave your comments     Method of enhancing myogenesis by electrical stimulation (7,483,749) Assignee | Inventor | Ask a question OR leave your comments     In vivo assay and molecular markers for testing the phenotypic stability of cell populations and selected cell populations for autologous transplantation (7,479,367) Assignee | Inventor | Ask a question OR leave your comments     Method of judging leukemia, pre-leukemia or aleukemic malignant blood disease and diagnostic therefor (7,479,371) Assignee | Inventor | Ask a question OR leave your comments     Method for enhancing keratinocyte stem cells (7,476,538) Assignee | Inventor | Ask a question OR leave your comments     Monoclonal antibodies to mesenchymal stem cells (7,476,540) Assignee | Inventor | Ask a question OR leave your comments     Remedies for ischemic disease (7,473,425) Assignee | Inventor | Ask a question OR leave your comments     Protocols for making hepatocytes from embryonic stem cells (7,473,555) Assignee | Inventor | Ask a question OR leave your comments     Compositions and methods for wound healing (7,473,414) Assignee | Inventor | Ask a question OR leave your comments     View all 1384 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     Periodontal Ligament Mesenchymals are Immune Suppressive 21 hours ago     StemCellPatents.com Applauds ISCO 3 days ago     Autologous Adipose for Multiple Sclerosis January 26th     Preventing Diabetes Associated Cardiac Dysfunction by MSC January 18th     Selecting Potent Immune Suppressive Mesenchymal Stem Cells January 17th     Read more news on StemCellPatents.com     LATEST JOBS POSTS     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com. Media Partnerships (NEW) (BETA) ------------------------------------------------------------ To unsubscribe, click here. Delivered: Monday February 2nd, 2009 @ 15:10:26 EST