|  |        International Stem Cell Corporation (OTCBB:ISCO) announced on December        30 that it had received the first $1 million tranche of an anticipated        private equity financing of up to $5 million to be funded over the next        several months.  Officials of the Company commented today on the        significance of that funding.             "This is a first major step toward the Company's goal of becoming        financially self-sufficient," said Kenneth Aldrich,  CEO of the Company.         Mr.  Aldrich noted that the anticipated $5 million of funding is targeted        toward three objectives: (1) eliminating $1 million of outstanding        secured debt; (2) supporting critical first quarter pre-clinical trials        that could be instrumental in enabling corporate joint venture        financing; and (3) providing marketing and expansion capital designed to        increase revenues from the Company's "Lifeline" subsidiary,  which makes        and sells specialty cells and growth media.             "Although additional financing will be needed in 2009 to reach our goal,         we believe our Lifeline subsidiary has the ability to bring the company        to profitability within 2 years and support the clinical research of the        company thereafter," said Jeffrey Janus,  President and Chief Operating        Officer of ISCO and CEO of its Lifeline subsidiary.             The current financing is in the form of a new class of Convertible        Preferred Stock,  convertible into common stock at $0.25/share.  The new        Preferred Stock carries an initial dividend of 10% per annum,  reducing        to 6% in two years,  payable quarterly.  The sale of the Preferred is        scheduled to close on the following schedule: (1) $1,000,000 was funded        December 30,  2008; (2) subject to determination by the Investors that        there has been no material adverse event with respect to the Company,         $1,000,000 will be funded February 5,  2009; and (3) at the Investors'        discretion,  three additional tranches of $1,000,000 each will be funded        on March 20,  2009,  June 30,  2009 and September 20,  2009.  "Because our        Investors will be actively involved with current management in operating        the company,  with opportunity to participate in all critical decisions,         we expect that all tranches will be funded as scheduled," said Mr.         Aldrich.             Pursuant to the terms of the financing agreement,  on December 30,  2008        the Company appointed Mr.  Andrei Semechkin (as the designee of the        holders of Series D Preferred) to the Board of Directors for a term that        expires at the next annual meeting of stockholders,  and entered into an        Employment Agreement with Mr.  Semechkin.  Because the financing agreement        provides for the size of the Board to remain at seven directors,         Mr.  Edward O.  Hunter resigned from the Board,  but will continue to serve        the Company as a member of the Company's Financial Advisory Board.             "Mr.  Semechkin will add extensive business and international experience        to our Board,  and,  although we will greatly miss Mr.  Hunter's direct        participation on the Board itself,  his willingness to maintain a high        level of involvement with the Company will mean we have not lost the        benefit of his experience and wisdom," said Mr.  Aldrich.             Further details are available in the Company's Form 8-K to be filed with        the SEC January 5,  2009.             ISCO is the creator and developer of a new class of stem cells that        remove two of the greatest barriers to the therapeutic use of stem        cells: 1) immune rejection and 2) the ethical issues that surround the        use of embryonic stem cells.  ISCO makes its cells available to qualified        researchers worldwide,  and its technology,  called "Parthenogenesis",         results in the creation of cell lines that may allow cells to be matched        to hundreds of millions of people without destroying a viable human        embryo.      ABOUT INTERNATIONAL STEM CELL CORPORATION (ISCO.OB):        International Stem Cell Corporation is a California biotechnology        company focused on developing therapeutic and research products.  ISCO's        technology,  Parthenogenesis,  results in the creation of        pluripotent human stem cell lines from unfertilized human eggs.  ISCO        scientists have created the first Parthenogenetic homozygous stem        cell line (phSC-Hhom-4) that can be a source of therapeutic cells        that will minimize immune rejection after transplantation into hundreds        of millions of individuals of differing sexes,  ages and racial groups.         These advancements offer the potential to create the first true "Stem        Cell Bank" and address ethical issues by eliminating the need to use or        destroy fertilized embryos.  ISCO also produces and markets specialized        cells and growth media worldwide for therapeutic research through its        subsidiary Lifeline Cell Technology.  For more information,  visit the        ISCO website at: www.internationalstemcell.com.             To subscribe to receive ongoing corporate communications please click on        the following link: http://www.b2i.us/irpass.asp?BzID=1468&to=ea&s=0.      FORWARD-LOOKING STATEMENTS: Statements pertaining to anticipated future financial and/or        operating results,  future growth in research,  technology,  clinical        development and potential joint venture and other opportunities for the        company and its subsidiary,  along with other statements about the future        expectations,  beliefs,  goals,  plans,  or prospects expressed by        management constitute forward-looking statements.  Any statements that        are not historical fact (including,  but not limited to statements that        contain words such as "will," "believes," "plans," "anticipates,"        "expects," "estimates,") should also be considered to be forward-looking        statements.  Forward-looking statements involve risks and uncertainties,         including,  without limitation,  risks inherent in the development and/or        commercialization of potential products,  uncertainty in the results of        clinical trials or regulatory approvals,  need and ability to obtain        future capital,  application of capital resources among competing uses,         and maintenance of intellectual property rights.  Actual results may        differ materially from the results anticipated in these forward-looking        statements and as such should be evaluated together with the many        uncertainties that affect the company's business,  particularly those        mentioned in the cautionary statements found in the company's Securities        and Exchange Commission filings.  The company disclaims any intent or        obligation to update these forward-looking statements. 
        International Stem Cell CorporationKenneth C.  Aldrich,  Chairman,         CEO,  760-940-6383
 kaldrich@intlstemcell.com
 William        Adams,  Chief Financial Officer,  760-940-6383
 wadams@intlstemcell.com
 or
 The        Investor Relations Group
 Adam S.  Holdsworth,  212-825-3210 (Investor        Relations)
 Laura Colontrelle,  212-825-3210 (Media Relations)
 lcolontrelle@investorrelationsgroup.com
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