January 2009 Volume 16 Number 1, pp 1 - 163
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NEWS AND COMMENTARY
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Cystic fibrosis: Ferreting with fibroblasts for cystic fibrosis
U Griesenbach and E W F W Alton
http://links.ealert.nature.com/ctt?kn=89&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
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REVIEW
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Progress & Prospects: Gene therapy in aging
S I S Rattan and R Singh
Abstract: http://links.ealert.nature.com/ctt?kn=32&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=13&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
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ORIGINAL ARTICLES
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Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition
of retinal neovascularization
P Pechan, H Rubin, M Lukason, J Ardinger, E DuFresne, W W Hauswirth,
S C Wadsworth and A Scaria
Abstract: http://links.ealert.nature.com/ctt?kn=8&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=36&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion
cell survival in experimental glaucoma
Y Munemasa, J H Ahn, J M K Kwong, J Caprioli and N Piri
Abstract: http://links.ealert.nature.com/ctt?kn=54&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=100&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Herpes simplex virus vector-mediated delivery of neurturin rescues
erectile dysfunction of cavernous nerve injury
R Kato, D Wolfe, C H Coyle, J B Wechuck, P Tyagi, T Tsukamoto, J B Nelson,
J C Glorioso, M B Chancellor and N Yoshimura
Abstract: http://links.ealert.nature.com/ctt?kn=25&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=67&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Transplantation of BMSCs expressing hPDGF-A//hBD2 promotes wound healing
in rats with combined radiation-wound injury
L Hao, J Wang, Z Zou, G Yan, S Dong, J Deng, X Ran, Y Feng, C Luo,
Y Wang and T Cheng
Abstract: http://links.ealert.nature.com/ctt?kn=103&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=28&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
A small regulatory element from chromosome 19 enhances liver-specific
gene expression
C Li, M Hirsch, P Carter, A Asokan, X Zhou, Z Wu and R J Samulski
Abstract: http://links.ealert.nature.com/ctt?kn=1&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=94&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Gene delivery into ischemic myocardium by double-targeted lipoplexes with
anti-myosin antibody and TAT peptide
Y T Ko, W C Hartner, A Kale and V P Torchilin
Abstract: http://links.ealert.nature.com/ctt?kn=81&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=53&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Enhancing transduction of the liver by adeno-associated viral vectors
A C Nathwani, M Cochrane, J McIntosh, C Y C Ng, J Zhou, J T Gray and A M Davidoff
Abstract: http://links.ealert.nature.com/ctt?kn=83&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=111&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Doxycycline-controlled splicing modulation by regulated antisense U7 snRNA
expression cassettes
J Marquis, S S Kampfer, L Angehrn and D Schumperli
Abstract: http://links.ealert.nature.com/ctt?kn=26&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=110&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Microvascular free tissue transfer for gene delivery: in vivo evaluation
of different routes of plasmid and adenoviral delivery
V K Agrawal, K M Copeland, Y Barbachano, A Rahim, R Seth, C L White,
M Hingorani, C M Nutting, M Kelly, P Harris, H Pandha, A A Melcher,
R G Vile, C Porter and K J Harrington
Abstract: http://links.ealert.nature.com/ctt?kn=66&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=52&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Lentiviral gene transfer to reduce atherosclerosis progression by
long-term CC-chemokine inhibition
C A Bursill, E McNeill, L Wang, O C Hibbitt, R Wade-Martins,
D J Paterson, D R Greaves and K M Channon
Abstract: http://links.ealert.nature.com/ctt?kn=84&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=72&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Extended release of adenovirus from silica implants in vitro and in vivo
L Kangasniemi, M Koskinen, M Jokinen, M Toriseva, R Ala-Aho, V-M Kahari,
H Jalonen, S Yla-Herttuala, H Moilanen, U-H Stenman, I Diaconu, A Kanerva,
S Pesonen, T Hakkarainen and A Hemminki
Abstract: http://links.ealert.nature.com/ctt?kn=87&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=24&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Transgene optimization significantly improves SIN vector titers, gp91phox
expression and reconstitution of superoxide production in X-CGD cells
B Moreno-Carranza, M Gentsch, S Stein, A Schambach, G Santilli, E Rudolf,
M F Ryser, S Haria, A J Thrasher, C Baum, S Brenner and M Grez
Abstract: http://links.ealert.nature.com/ctt?kn=92&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=98&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Microwave irradiation enhances gene and oligonucleotide delivery and
induces effective exon skipping in myoblasts
T J Doran, P J Lu, G S Vanier, M J Collins, B Wu and Q L Lu
Abstract: http://links.ealert.nature.com/ctt?kn=64&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=30&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates
infarct size and apoptosis following myocardial infarct
J W Yockman, D Choi, M G Whitten, C W Chang, A Kastenmeier, H Erickson,
A Albanil, M Lee, S W Kim and D A Bull
Abstract: http://links.ealert.nature.com/ctt?kn=6&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=12&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
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SHORT COMMUNICATIONS
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PET imaging of thymidine kinase gene expression in the liver of non-human
primates following systemic delivery of an adenoviral vector
A Fontanellas, S Hervas-Stubbs, A Sampedro, M Collantes, A Azpilicueta,
I Mauleon, A Paneda, G Quincoces, J Prieto, I Melero and I Penuelas
Abstract: http://links.ealert.nature.com/ctt?kn=63&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=15&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Prevention of interferon-stimulated gene expression using microRNA-designed hairpins
M Bauer, N Kinkl, A Meixner, E Kremmer, M Riemenschneider, H Forstl, T Gasser and M Ueffing
Abstract: http://links.ealert.nature.com/ctt?kn=55&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=80&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune
system (Rag-2-//-[gamma]c-//-) mouse model
O ter Brake, N Legrand, K J von Eije, M Centlivre, H Spits, K Weijer,
B Blom and B Berkhout
Abstract: http://links.ealert.nature.com/ctt?kn=74&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=76&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
An efficient transfection method for mouse embryonic stem cells
B S Ko, T C Chang, S K Shyue, Y C Chen and J Y Liou
Abstract: http://links.ealert.nature.com/ctt?kn=99&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=68&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative
HIV-1-derived vectors
G Berger, C Goujon, J-L Darlix and A Cimarelli
Abstract: http://links.ealert.nature.com/ctt?kn=77&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=109&m=30907748&r=MTU3MzQ1MTAxMQS2&b=2&j=NDQ5MzkzNjYS1&mt=1&rt=0
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