January 2009 Volume 10 Number 1, pp 1-101
(c) Copyright
2009 by the European Molecular Biology Organization
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Contents: Volume 10,
Number 1 (January 2009)
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EDITORIAL
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A letter to Darwin.
Frank Gannon
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SCIENCE AND SOCIETY
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VIEWPOINTS
The state of h index research. Is the h index the ideal way to measure research performance?.
Lutz Bornmann & Hans-Dieter Daniel
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Managing the unimaginable. Regulatory responses to the challenges posed by synthetic biology and synthetic genomics.
Gabrielle N Samuel, Michael J Selgelid & Ian Kerridge
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INTERVIEW
A decade of stem-cell research. An interview with John Gearhart, Director of the Institute for Regenerative Medicine at the University of Pennsylvania, USA.
Howard Wolinsky
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ANALYSES
The good, the bad and the ugly red tape of biomedical research. How could regulators lower bureaucratic hurdles in clinical research without compromising the safety of patients?.
Mark Greener
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Reading the metabolic fine print. The application of metabolomics to diagnostics, drug research and nutrition might be integral to improved health and personalized medicine.
Philip Hunter
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BOOK REVIEW
Science-in-theatre-in-science.
Suresh Rattan
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REVIEWS
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MEETING REPORTS
Epigenetics and the control of multicellularity. Workshop on Chromatin at the Nexus of Cell Division and Differentiation.
Gunter Reuter & Giacomo Cavalli
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MHC molecules lead many lives. Workshop on MHC Class I Molecules at the interface between Biology & Medicine.
Paul Bowness, Steve Caplan & Michael Edidin
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Old and new faces of the nucleolus. Workshop on the Nucleolus and Disease.
Lesley A Stark & Michael Taliansky
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LITERATURE REPORT
Arrestins as adaptors for ubiquitination in endocytosis and sorting.
Rohit Mittal & Harvey T McMahon
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REVIEW
Think locally: control of ubiquitin-dependent protein degradation in neurons.
Alexandra Segref & Thorsten Hoppe
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SCIENTIFIC REPORTS
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GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function.
Jing Liang, Hua Zhang, Yu Zhang, Ying Zhang & Yongfeng Shang
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A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor.
Yi Deng, Marie-Pierre Golinelli-Cohen, Elena Smirnova & Catherine L Jackson
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Quinone reductase acts as a redox switch of the 20S yeast proteasome.
Sonja Sollner, Markus Schober, Andrea Wagner, Anna Prem, Lucie Lorkova, Bruce A Palfey, Michael Groll & Peter Macheroux
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Cellular senescence and organismal ageing in the absence of p21CIP1/WAF1 in ku80-/- mice.
Bo Zhao, Erica K Benson, Ruifang Qiao, Xing Wang, Sunchin Kim, James J Manfredi, Sam W Lee & Stuart A Aaronson
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SHARP1/DEC2 inhibits adipogenic differentiation by regulating the activity of C/EBP.
Neriman Tuba Gulbagci, Li Li, Belinda Ling, Suma Gopinadhan, Martin Walsh, Moritz Rossner, Klaus-Armin Nave & Reshma Taneja
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DNA-PK suppresses a p53-independent apoptotic response to DNA damage.
Kay E Gurley, Russell Moser, Yansong Gu, Paul Hasty & Christopher J Kemp
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Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease.
Nikolai D Belyaev, Natalia N Nalivaeva, Natalia Z Makova & Anthony J Turner
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ERRATUM
Blm10 binds to pre-activated proteasome core particles with open gate conformation.
Andrea Lehmann, Katharina Jechow & Cordula Enenkel
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CORRIGENDUM
Necessary and sufficient factors for the import of transfer RNA into the kinetoplast mitochondrion.
Saikat Mukherjee, Sudarshana Basu, Pratik Home, Gunjan Dhar & Samit Adhya
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