November 2008 Volume 6 Number 11
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This month's FEATURED article:
Hydrothermal vents and the origin of life
William Martin, John Baross, Deborah Kelley and Michael J. Russell
p805 | doi:10.1038/nrmicro1991
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72c0ED
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In this issue
p793 | doi:10.1038/nrmicro2026
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72d0EE
Editorial: Historical archive made free for all
p794 | doi:10.1038/nrmicro2027
The archive of the International Journal of Systematic and
Evolutionary Microbiology (IJSEM) has been made available free online,
which should be a boon for scientists, historians and the public.
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72e0EF
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RESEARCH HIGHLIGHTS
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Cell Polarity: Sticky poles
p795 | doi:10.1038/nrmicro2022
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72f0EG
Prions: Crossing borders
p796 | doi:10.1038/nrmicro2018
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72g0EH
Fungal Biology: Fungal shape-shifting
p796 | doi:10.1038/nrmicro2024
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72h0EI
Innate Immunity: Getting in TRIM to fight retroviruses
p797 | doi:10.1038/nrmicro2017
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72i0EJ
IN BRIEF
Microbial ecology | Bioremediation | Fungal pathogenesis
p798 | doi:10.1038/nrmicro2020
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72j0EK
Infectious Disease: Finding the keys to the placental barrier
p798 | doi:10.1038/nrmicro2025
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72k0EL
Antimicrobials: Z-ring Achilles' heel for MRSA
p799 | doi:10.1038/nrmicro2016
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72l0EM
Bacterial Ecology: Dental double act
p799 | doi:10.1038/nrmicro2023
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72m0EN
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NEWS AND ANALYSIS
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GENOME WATCH
Sequence data swell for nematodes
Christiane Hertz-Fowler and Arnab Pain
p800 | doi:10.1038/nrmicro2021
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72n0EO
DISEASE WATCH
In the News
p802 | doi:10.1038/nrmicro2028
http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72o0EP
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REVIEWS
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Hydrothermal vents and the origin of life
William Martin, John Baross, Deborah Kelley and Michael J. Russell
p805 | doi:10.1038/nrmicro1991
Hydrothermal vent systems, which can support life in the absence of
photosynthesis, are today inhabited by animals that form symbioses
with lithoautotrophic microorganisms from which they obtain chemical energy.
These hydrothermal systems might resemble the earliest microbial
ecosystems on the Earth. Here, Martin, Baross, Kelley and Russell
review how understanding these complex systems might inform our
understanding of the origins of life itself.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72p0EQ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72c0ED
Avoiding the void: cell-to-cell spread of human viruses
Quentin Sattentau
p815 | doi:10.1038/nrmicro1972
Many viruses that are pathogenic for humans, including HIV-1,
herpes simplex virus and measles, can disseminate by moving directly
from cell to cell. Quentin Sattentau discusses the mechanisms of viral
cell-to-cell spread and the implications for viral dissemination, immune
evasion and pathogenesis.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72q0ER
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72r0ES
The rise and fall of bacterial clones: Streptococcus pneumoniae
Birgitta Henriques-Normark, Christel Blomberg, Jessica Dagerhamn, Patrick Bättig and Staffan Normark
p827 | doi:10.1038/nrmicro2011
Clonal types of pathogenic bacteria differ in their ability to colonize,
spread and cause disease in hosts. The evolution of bacterial clones and
factors that contribute to the clonal spread of bacteria are discussed
in this article, together with the relevance of bacterial clones to the
progression of disease.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72s0ET
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72t0EU
Swimming with protists: perception, motility and flagellum assembly
Michael L. Ginger, Neil Portman and Paul G. McKean
p838 | doi:10.1038/nrmicro2009
The motility that is afforded by flagella and cilia is widespread among
unicellular eukaryotes. In this Review, Ginger and colleagues describe
the structure of the flagellum, its metabolic activity, different synthesis
pathways and flagellar functions that extend beyond motility.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72u0EV
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72v0EW
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PERSPECTIVES
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INNOVATION
Recombineering mycobacteria and their phages
Julia C. van Kessel, Laura J. Marinelli and Graham F. Hatfull
p851 | doi:10.1038/nrmicro2014
Genetic modification of mycobacteria is a difficult process. In this innovation,
van Kessel and colleagues describe a new system of recombineering that facilitates
the production of mutants in mycobacteria and mycobacteriophages.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72w0EX
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72x0EY
SCIENCE AND SOCIETY
Post-genomic challenges for collaborative research in infectious diseases
Iruka N. Okeke and John Wain
p858 | doi:10.1038/nrmicro1989
Collaborations of scientists from developed countries and developing countries
have had great success, but often have trouble getting established. Here,
Iruka Okeke and John Wain describe the benefits of collaborations, the
hurdles faced in their initiation, ways to promote them and the programmes
that are already in place to develop them.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72y0EZ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B72z0Ea
OPINION
What really happens to dendritic cells during malaria?
Michelle N. Wykes and Michael F. Good
p864 | doi:10.1038/nrmicro1988
The functions of dendritic cells during malaria have been the subject of
intensive investigations, the results of which have been controversial.
Here, Michelle Wykes and Michael Good propose that the species and strain
of Plasmodium are some of the key factors that affect dendritic cell function.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B7210EN
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eoFS0Xztnp0Hjf0B7220EO
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