Cleansing Bone Marrow With a Virus

View this message online Hello manoj kumar valluru, Our friends from up North have done it again ! For one reason or another Calgary Canada seems to be the birthplace of a lot of interesting patents.  Stem Cell Therapeutics, who you may remember, not only have patents on various hormones that activate endogenous stem cells, such as PACAP, Prolactin, and EPO, but are actually in Phase II clinical trials using such approaches in stroke.  Last week another interesting Calgary company, Oncolytics, made news by being issued a patent (# 7,431,932) on the used of reovirus to selectively purge bone marrow cells of contaminating cancer cells.  This is very interesting technology since reovirus possesses a great safety profile and already is in clinical trials by the company. Other patents of interest, Novocell was issued #7,432,104 teaching how to grow ES cells on human feeder cells, Ian Wilmut recieved another patent on nuclear transfer, #7,432,415, and a new method of stimulating hematopoietic stem cells post-chemo was revealed, #7,432,236, through the administration of the peptide vasostatin.   On the academic publication front, a neat paper came out last week showing that it is possible to target stem cells to apoptotic cells through conjugation of Annexin-V to stem cells.      Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions     Patent Number: 7,431,932 Assignee | Inventor Activation of innate immune responses is associated in some situations with anti-tumor effects.  It is known that viruses activate various cells of the innate immune system such as interferon producing plasmacytoid dendritic cells and natural killer...[Read More] Ask a question OR leave your comments.     Making stem cells find apoptotic cells Wednesday October 8th, 2008 @ 21:06:39 EST Torino, Italy - Hematopoietic stem cells and mesenchymal stem cells are known to more or less find their way to injured tissue.  This is one of the reasons why companies such as Osiris can get away with simply intravenously injecting their...[Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News         RECENTLY ADDED PATENTS     Methods for the culture of human embryonic stem cells on human feeder cells (7,432,104) Assignee | Inventor | Ask a question OR leave your comments     Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions (7,431,932) Assignee | Inventor | Ask a question OR leave your comments     Vasostatin as marrow protectant (7,432,236) Assignee | Inventor | Ask a question OR leave your comments     Unactivated oocytes as cytoplast recipients for nonprimate mammalian and pig nuclear transfer (7,432,415) Assignee | Inventor | Ask a question OR leave your comments     Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion (7,429,383) Assignee | Inventor | Ask a question OR leave your comments     Methods of controlling proliferation and differentiation of stem and progenitor cells (7,429,489) Assignee | Inventor | Ask a question OR leave your comments     Methods of cancer diagnosis and therapy targeted against a cancer stem line (7,427,400) Assignee | Inventor | Ask a question OR leave your comments     Methods for identifying stem cells based on nuclear morphotypes (7,427,502) Assignee | Inventor | Ask a question OR leave your comments     Method of treating brain tissue damages (7,427,597) Assignee | Inventor | Ask a question OR leave your comments     Method of enhancing proliferation and/or hematopoietic differentiation of stem cells (7,427,603) Assignee | Inventor | Ask a question OR leave your comments     View all 1343 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     Making stem cells find apoptotic cells 4 days ago     ES cells as immune modulators: look out MSCs !! October 5th     Cancer Vaccine Against Aurora Kinase October 2nd     Selecting for better mesenchymal stem cells September 27th     Exercise Increases Neural Stem Cells September 22nd     Read more news on StemCellPatents.com     LATEST JOBS POSTS     Attorney- Patent Litigation Associate Crescent Strategic Resources     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com.   RMSC 2008 World Congress The 3rd Annual Stem Cells World Congress The Stem Cell Meeting Media Partnerships We welcome your comments and suggestions! Tell us here. ------------------------------------------------------------ To unsubscribe, click here. Delivered: Monday October 13th, 2008 @ 10:55:05 EST