September 2008 Volume 22 Number 9, pp 1651 - 1812
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SPOTLIGHT REVIEW
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Pathogenesis and progression of monoclonal gammopathy of undetermined
significance
J Blade, L Rosinol, M T Cibeira and C F de Larrea
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5H40EZ
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5H50Ea
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REVIEW
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Immunotherapy for myeloid leukemias: current status and future
directions
K el-Shami and B D Smith
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5H60Eb
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5H70Ec
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ORIGINAL ARTICLES
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Pharmacokinetic, pharmacodynamic and intracellular effects of
PEG-asparaginase in newly diagnosed childhood acute lymphoblastic
leukemia: results from a single agent window study
I M Appel, K M Kazemier, J Boos, C Lanvers, J Huijmans, A J P Veerman,
E van Wering, M L den Boer and R Pieters
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5H80Ed
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IA0En
A pilot pharmacokinetic study of oral azacitidine
G Garcia-Manero, M L Stoltz, M R Ward, H Kantarjian and S Sharma
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IB0Eo
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IC0Ep
Prognostic role of glutathione S-transferase polymorphisms in acute
myeloid leukemia
M T Voso, S Hohaus, F Guidi, E Fabiani, F D'Alo, S Groner, D Spath, K
Doehner, G Leone, H Doehner and R F Schlenk
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5ID0Eq
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IE0Er
Prenatal origin of childhood acute lymphoblastic leukemia, association
with birth weight and hyperdiploidy
B Gruhn, J W Taub, Y Ge, J F Beck, R Zell, R Hafer, F H Hermann, K-M
Debatin and D Steinbach
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IF0Es
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IG0Et
PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase
and mTOR, has antileukemic activity in AML
S Park, N Chapuis, V Bardet, J Tamburini, N Gallay, L Willems, Z A
Knight, K M Shokat, N Azar, F Viguie, N Ifrah, F Dreyfus, P Mayeux, C
Lacombe and D Bouscary
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IH0Eu
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5II0Ev
On the use of lonafarnib in myelodysplastic syndrome and chronic
myelomonocytic leukemia
E J Feldman, J Cortes, D J DeAngelo, T Holyoake, B Simonsson, S G
O'Brien, J Reiffers, A R Turner, G J Roboz, J H Lipton, F Maloisel, P
Colombat, G Martinelli, J L Nielsen, S Petersdorf, F Guilhot, J
Barker, P Kirschmeier, E Frank, P Statkevich, Y Zhu, S Loechner and A
List
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IJ0Ew
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IK0Ex
BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic
GX15-070 (Obatoclax) and reduces its synergistic interaction with
bortezomib in chronic lymphocytic leukemia cells
P Perez-Galan, G Roue, M Lopez-Guerra, M Nguyen, N Villamor, E
Montserrat, G C Shore, E Campo and D Colomer
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IL0Ey
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IM0Ez
Hematopoietic stem cells and progenitors of chronic myeloid leukemia
express leukemia-associated antigens: implications for the
graft-versus-leukemia effect and peptide vaccine-based immunotherapy
A S M Yong, K Keyvanfar, R Eniafe, B N Savani, K Rezvani, E M Sloand,
J M Goldman and A J Barrett
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IN0E1
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IO0E2
The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by
Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in
p53 wild-type AML
K Kojima, M Shimanuki, M Shikami, I J Samudio, V Ruvolo, P Corn, N
Hanaoka, M Konopleva, M Andreeff and H Nakakuma
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IP0E3
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IQ0E4
Spongistatin 1: a new chemosensitizing marine compound that degrades
XIAP
L Schyschka, A Rudy, I Jeremias, N Barth, G R Pettit and A M Vollmar
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IR0E5
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IS0E6
Pathway activation patterns in diffuse large B-cell lymphomas
S Bentink, S Wessendorf, C Schwaenen, M Rosolowski, W Klapper, A
Rosenwald, G Ott, A H Banham, H Berger, A C Feller, M-L Hansmann, D
Hasenclever, M Hummel, D Lenze, P Moller, B Stuerzenhofecker, M
Loeffler, L Truemper, H Stein, R Siebert and R Spang
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IT0E7
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IU0E8
Tyrosine kinase inhibition in diffuse large B-cell lymphoma: molecular
basis for antitumor activity and drug resistance of dasatinib
C Yang, P Lu, F Y Lee, A Chadburn, J C Barrientos, J P Leonard, F Ye,
D Zhang, D M Knowles and Y L Wang
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IV0EA
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IW0EB
Incorporation of the bone marker carboxy-terminal telopeptide of
type-1 collagen improves prognostic information of the International
Staging System in newly diagnosed symptomatic multiple myeloma
C Jakob, J Sterz, P Liebisch, M Mieth, J Rademacher, A Goerke, U
Heider, C Fleissner, M Kaiser, I von Metzler, C Muller and O Sezer
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IX0EC
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IY0ED
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LETTERS TO THE EDITOR
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Identification of marker genes including RUNX3 (AML2) that
discriminate between different myeloproliferative neoplasms and normal
individuals
C I Muller, Q T Luong, L-Y Shih, L C Jones, J C Desmond, N Kawamata, O
Tcherniantchouk, Q Liu, K Ito, M Osato, Y Ito, A Tefferi, S de Vos and
H P Koeffler
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5IZ0EE
Association between high expression of natural killer related-genes
(NCAM/CD94) and early death during induction in children with acute
myeloid leukemia
L LoNigro, E Mirabile, S Munda, M Barchitta, D Bottino, A Fazzio, A Di
Cataldo, A Agodi and G Schiliro
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ia0EL
Fludarabine combination therapy for follicular lymphoma followed by
acute myeloid leukemia: two further case records
P Bernardeschi, G Fiorentini, P Dentico, S Rossi, G Turrisi, A Del
Conte, P G Giannessi, G Giustarini and I Montenora
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ib0EM
Successful treatment of multicentric Castleman's disease with combined
immunochemotherapy in an AIDS patient with multiorgan failure
S M Schmidt, A Raible, F Kortum, F Mayer, R Riessen, P Adam, M Gregor
and A L Bissinger
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ic0EN
Allogeneic transplantation of multiple umbilical cord blood units in
adults: role of pretransplant-mixed lymphocyte reaction to predict
host-vs-graft rejection
L R Fanning, Y Hegerfeldt, M Tary-Lehmann, M Lesniewski, J
Maciejewski, R P Weitzel, M Kozik, M Finney, H M Lazarus, P Paul, M Z
Ratajczak, H J Meyerson and M J Laughlin
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Id0EO
TG101348, a JAK2-selective antagonist, inhibits primary hematopoietic
cells derived from myeloproliferative disorder patients with
JAK2V617F, MPLW515K or JAK2 exon 12 mutations as well as mutation
negative patients
T L Lasho, A Tefferi, J D Hood, S Verstovsek, D G Gilliland and A
Pardanani
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ie0EP
Two cell lines of t(8;21) acute myeloid leukemia with activating KIT
exon 17 mutation: models for the 'second hit' hypothesis
H Becker, D Pfeifer, J D Afonso, S D Nimer, H Veelken, M Schwabe and M
Lubbert
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5If0EQ
BIC is processed efficiently to microRNA-155 in Burkitt lymphoma cells
T Zhang, K Nie and W Tam
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ig0ER
Transformation of severe congenital neutropenia to early acute
lymphoblastic leukemia in a patient with HAX1 mutation and without
G-CSF administration or receptor mutation
S Yetgin, L Olcay, A Koc and M Germeshausen
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ih0ES
Polymorphisms in folate-related genes: association with side effects
of high-dose methotrexate in childhood acute lymphoblastic leukemia
L Huang, W J E Tissing, R de Jonge, B D van Zelst and R Pieters
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ii0ET
Corticosteroids in the prevention of graft-vs-host disease after
allogeneic myeloablative stem cell transplantation: a systematic
review and meta-analysis
S Quellmann, G Schwarzer, K Hubel, A Engert and J Bohlius
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ij0EU
Rac guanosine triphosphatases represent a potential target in AML
L U W Muller, R J Schore, Y Zheng, E K Thomas, M-O Kim, J A Cancelas,
Y Gu and D A Williams
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Ik0EV
Multiple sub-microscopic genomic lesions are a universal feature of
chronic myeloid leukaemia at diagnosis
J S Khorashad, V A De Melo, H Fiegler, G Gerrard, D Marin, J F
Apperley, J M Goldman, L Foroni and A G Reid
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Il0EW
Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2
in secondary T-cell acute lymphoblastic leukemia
M Metzler, M S Staege, L Harder, D Mendelova, J Zuna, E Fronkova, C
Meyer, T Flohr, D Bednarova, J Harbott, T Langer, S Gesk, J Trka, R
Siebert, T Dingermann, R Marschalek, C Niemeyer and W Rascher
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Im0EX
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CORRIGENDA
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Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2
in secondary T-cell acute lymphoblastic leukemia
M Metzler, M S Staege, L Harder, D Mendelova, J Zuna, E Fronkova, C
Meyer, T Flohr, D Bednarova, J Harbott, T Langer, S Gesk, J Trka, R
Siebert, T Dingermann, R Marschalek, C Niemeyer and W Rascher
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5In0EY
Incorporation of the bone marker carboxy-terminal telopeptide of
type-1 collagen improves prognostic information of the International
Staging System in newly diagnosed symptomatic multiple myeloma
C Jakob, J Sterz, P Liebisch, M Mieth, J Rademacher, A Goerke, U
Heider, C Fleissner, M Kaiser, I von Metzler, C Muller and O Sezer
http://ealerts.nature.com/cgi-bin24/DM/y/enS50Xztnp0Hi20B5Io0EZ
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