Teeth becoming brain

View this message online Dear manoj kumar valluru, An interesting paper of relevance to our field was published last week describing neural in vivo differentiation of tooth derived stem cells, and perhaps more interesting, activation and recruitment of endogenous neural progenitors. This is the second paper demonstrating in vivo activity of this type of cell, a while ago we discussed the paper demonstrating similar stem cells possessing cardiac regenerative activity. Also interesting was a patent (#7,408,095) issued to the company Phylonix Pharmaceuticals covering the use of pre-immune zebrafish as an alternative immune deficient host for studying human cells, particularly cancer. Looks like the NOD-SCID mice will be out of a job !! (joke). Another patent (#7,408,039) was issued covering the use of costimulatory blockade (CD28-CD80/CD86) or (CD40L-CD40) together with antibodies to CD2 as a method of blocking graft versus host disease after cytoreductive therapy.   Methods for introducing heterologous cells into fish to determine if the heterologous cells contain cancer cells or a pathogen     Patent Number: 7,408,095 Assignee | Inventor In general it is quickly forgotten that the biggest contribution of embryonic stem cell technology to medicine has not been in the area of actually generating therapeutics, but in development of model systems for studying diseases. It was only through the generation of knockout and transgenic animals that we as biologists were able to start...[Read More] Ask a question OR leave your comments.     Tooth in the Brain: Tooth Mesenchymal Stem Cells Made into Neurons Sunday August 10th, 2008 @ 15:18:00 EST Kaohsiung, Taiwan - The ability of mesenchymal stem cells to differentiate into neurons and neuron-like cells has been documented.  For example, mesenchymal stem cells have been demonstrated to be beneficial in case reports of multiple sclerosis, as well as in early clinical...[Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News       RECENTLY ADDED PATENTS     Kits for treatment of hematologic disorders (7,408,039) Assignee | Inventor | Ask a question OR leave your comments     Methods for introducing heterologous cells into fish to determine if the heterologous cells contain cancer cells or a pathogen (7,408,095) Assignee | Inventor | Ask a question OR leave your comments     Cosmetic compositions (7,405,195) Assignee | Inventor | 1 Comment     Generation and use of dendritic cells (7,405,076) Assignee | Inventor | Ask a question OR leave your comments     Treatment of disease by inducing cell apoptosis (7,402,567) Assignee | Inventor | Ask a question OR leave your comments     Longevity and PAPP-A (7,402,724) Assignee | Inventor | Ask a question OR leave your comments     Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells (7,399,751) Assignee | Inventor | Ask a question OR leave your comments     Poly-Glu,Tyr for neuroprotective therapy (7,399,740) Assignee | Inventor | Ask a question OR leave your comments     Stem cell-specific promoters and their use (7,396,680) Assignee | Inventor | Ask a question OR leave your comments     Cell delivery patch for myocardial tissue engineering (7,396,537) Assignee | Inventor | Ask a question OR leave your comments     View all 1317 Stem Cell Patents on StemCellPatents.com     LATEST NEWS     Tooth in the Brain: Tooth Mesenchymal Stem Cells Made into Neurons 8 hours ago     Exosomes as a means of immune escape August 3rd     Mesenchymal Stem Cells Inhibiting Homeostatic Proliferation July 25th : 2 Comments     Clinical Trial of CD34 Stem Cells for Liver Failure July 20th     Interferon gamma as a "danger signal" July 13th     Read more news on StemCellPatents.com     LATEST JOBS POSTS     Research Assistant UAE University     Patent Proscecution Technology Specialist or Scientific Advisor Crescent Strategic Resources     Attorney- Patent Litigation Associate Crescent Strategic Resources     View the StemCellPatents.com Job Board   Thanks again for your help in supporting StemCellPatents.com. We welcome your comments and suggestions! Tell us here.     We can help get the word out. ------------------------------------------------------------ To unsubscribe, click here. Delivered: Sunday August 10th, 2008 @ 23:40:22 EST