September 2008 Volume 6 Number 9
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Nature Reviews Microbiology
Focus on Sustainability
In the past decade, global climate change has come to the forefront of the
political and social agenda owing to the growing realization that the Earth's
resources are being used in an unsustainable fashion.
Find out about the central role of microbial processes in sustainable development
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This month's FEATURED article:
Revisiting the host as a growth medium
Stacie A. Brown, Kelli L. Palmer and Marvin Whiteley
p613 | doi:10.1038/nrmicro1955
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28N0E3
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In this issue
p645 | doi:10.1038/nrmicro1983
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28O0E4
Editorial: Culture media
Chris Condayan
p646 | doi:10.1038/nrmicro1981
Chris Condayan explains how self-created audio and video content might enable
more microbiologists to share knowledge and news online.
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28P0E5
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RESEARCH HIGHLIGHTS
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Sociomicrobiology: Anti-social bacteria
p647 | doi:10.1038/nrmicro1974
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28Q0E6
Archaea: Kings of the sea floor?
p648 | doi:10.1038/nrmicro1973
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28R0E7
Viral pathogenesis: microRNA rides tandem
p648 | doi:10.1038/nrmicro1977
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28S0E8
Bacterial genetics: A hidden GEMM
p649 | doi:10.1038/nrmicro1976
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28T0EA
IN BRIEF
Prions | Biofilms | Bacterial pathogenesis
p649 | doi:10.1038/nrmicro1980
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28U0EB
Parasitology: Antigen switching joins the DOTs
p650 | doi:10.1038/nrmicro1975
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28V0EC
Pathogenesis: Buzzkill
p650 | doi:10.1038/nrmicro1979
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28W0ED
HIV: Editing HIV entry
p651 | doi:10.1038/nrmicro1970
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28X0EE
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NEWS AND ANALYSIS
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GENOME WATCH
Opportunity knocks
Helena Seth-Smith and Alan Walker
p652 | doi:10.1038/nrmicro1985
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28Y0EF
DISEASE WATCH
In the News
p654 | doi:10.1038/nrmicro1984
http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28Z0EG
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REVIEWS
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Revisiting the host as a growth medium
Stacie A. Brown, Kelli L. Palmer and Marvin Whiteley
p657 | doi:10.1038/nrmicro1955
What makes the human body a good growth medium for bacterial pathogens?
In this Review, Brown, Palmer and Whiteley outline how the host growth
environment affects disease and discuss the potential for targeting host
metabolic pathways for therapeutic development.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28a0EN
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28N0E3
Molecular mechanisms of mechanosensing and their roles in fungal contact sensing
Carol A. Kumamoto
p667 | doi:10.1038/nrmicro1960
The ability to sense contact with an appropriate surface contributes to the
ability of fungal pathogens such as Magnaporthe grisea and Candida albicans
to cause disease in their respective hosts. This Review discusses molecular
mechanisms of mechanosensitivity, the proteins involved and their putative
roles in fungal contact sensing.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28b0EO
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28c0EP
Towards nanomicrobiology using atomic force microscopy
Yves F. Dufrene
p674 | doi:10.1038/nrmicro1948
The nanoscale analysis of microbial cells using atomic force microscopy (AFM)
is emerging as an exciting, rapidly evolving research field. Specifically,
AFM allows us to address fundamental microbiological questions by observing
membrane proteins and live cells at high resolution.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28d0EQ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28e0ER
Protein-based organelles in bacteria: carboxysomes and related microcompartments
Todd O. Yeates, Cheryl A. Kerfeld, Sabine Heinhorst, Gordon C. Cannon and
Jessup M. Shively
p681 | doi:10.1038/nrmicro1913
Bacterial microcompartments consist of a protein shell that encapsulates
enzymes to form an 'organelle'. Recent structural analyses have begun
to provide insights into how one of these microcompartments, the carboxysome,
which houses ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) and
carbonic anhydrase, is built. This Review describes the structure and function
of bacterial microcompartments by focusing on carboxysomes.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28f0ES
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28g0ET
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PERSPECTIVES
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TIMELINE
Molecular eco-systems biology: towards an understanding of community function
Jeroen Raes and Peer Bork
p693 | doi:10.1038/nrmicro1935
Metagenomics has enabled researchers to compile inventories of viruses, bacteria
and archaea that inhabit specific niches. Here, the authors discuss the tools
that are needed for us to progress to an integrated understanding of microbial
ecosystems biology.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28h0EU
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28i0EV
OPINION
Architects of assembly: roles of Flaviviridae non-structural proteins in virion
morphogenesis
Catherine L. Murray, Christopher T. Jones and Charles M. Rice
p699 | doi:10.1038/nrmicro1928
The authors discuss a new hypothesis, based on a body of evidence that has
accumulated over the past 10 years, that non-structural proteins of RNA viruses,
such as hepatitis C and dengue, have roles in virion maturation and assembly.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28j0EW
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emun0Xztnp0Hje0B28k0EX
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