28 August 2008 Volume 454 Number 7208, pp1029-1150
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EDITORIALS
----------------------
Doubly endangered p1029
The landmark Endangered Species Act in the United States needs more
flexibility and fresh thinking -- but not of the kind being advocated
by the Bush administration.
doi:10.1038/4541029a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ff0EC
After Musharraf p1030
Pakistan's elected governments should break the habit of a lifetime
and give due priority to science.
doi:10.1038/4541030a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fg0ED
Future transport p1030
The hike in the price of oil means that new ways of fuelling transport
are no longer fantasy.
doi:10.1038/4541030b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fh0EE
----------------------
RESEARCH HIGHLIGHTS
----------------------
Biophysics: Water bomb p1032
doi:10.1038/4541032a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fi0EF
Electronics: Silicon enhancement p1032
doi:10.1038/4541032b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fj0EG
Evolutionary biology: Commonality and cuckoos p1032
doi:10.1038/4541032c
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fk0EH
Microbiology: Suffocating tuberculosis p1032
doi:10.1038/4541032d
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fl0EI
Particle physics: Antimatter bounces back p1032
doi:10.1038/4541032e
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fm0EJ
Evolution: Serotonin for mothers pp1032-1033
doi:10.1038/4541032f
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fn0EK
Palaeobiology: Megabite p1033
doi:10.1038/4541033a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fo0EL
Materials science: Finding focus p1033
doi:10.1038/4541033b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fp0EM
Geosciences: Soil sink surprise p1033
doi:10.1038/4541033c
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fq0EN
Zoology: Under pressure p1033
doi:10.1038/4541033d
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fr0EO
----------------------
JOURNAL CLUB
----------------------
Journal club p1033
John Harte
doi:10.1038/4541033e
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fs0EP
----------------------
NEWS
----------------------
Georgian science pays price of conflict p1034
Conflict with Russia puts reforms in jeopardy.
Quirin Schiermeier
doi:10.1038/4541034a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ft0EQ
Fresh doubts over T. rex chicken link p1035
Critics call on researchers to disclose protein spectra data.
Rex Dalton
doi:10.1038/4541035a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fu0ER
Do the locomotion pp1036-1037
Rail travel produces more than a third less emissions than road
transport — even though trains carry 7% of traffic, they emit just
0.2% of the carbon monoxide, 2% of nitrogen oxides and 1% of the
volatile organic compounds. Although electric passenger trains are
relatively green, most of the world's trains are used for haulage and
run on diesel. In the latest of our Future Transport series,
Duncan Graham-Rowe sees trains switching to a greener track.
doi:10.1038/4541036a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fv0ES
Death and life beneath the sea floor p1038
Viral action identified as key component in carbon cycle.
Heidi Ledford
doi:10.1038/4541038a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fw0ET
Snapshot: New window on the gamma-ray Universe p1038
GLAST provides first sky map – and gets a new name.
Eric Hand
doi:10.1038/4541038b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fx0EU
Q&A
Q & A: Too close for comfort p1039
In early 2002, the US Federal Bureau of Investigation (FBI) asked
the American Society for Microbiology to canvas its 43,000 members
for information about the 2001 anthrax mail attacks that killed five
people. Nancy Haigwood, now director of the Oregon National Primate
Research Center in Hillsboro, suggested that agents should investigate
microbiologist Bruce Ivins, who had been harassing her for more than
20 years. On 29 July, Ivins killed himself as authorities were close
to indicting him for the anthrax attacks.
Rex Dalton
doi:10.1038/4541039a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fy0EV
Rector sacked in Austrian stem-cell scandal p1041
doi:10.1038/4541041a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Fz0EW
Nuclear group to rule on Indian trade p1041
doi:10.1038/4541041b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F10EJ
NIH promises funds for cheaper DNA sequencing p1041
doi:10.1038/4541041c
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F20EK
Inquiry launched into Indian drug trials p1041
doi:10.1038/4541041d
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F30EL
Cracks spotted in Greenland's glaciers p1041
doi:10.1038/4541041e
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F40EM
Orion crash-landing leaves NASA hunting for clues p1041
doi:10.1038/4541041f
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F50EN
----------------------
NEWS FEATURES
----------------------
Genetics: The production line pp1042-1045
If more than 90% of the genome is 'junk' then why do cells make so
much RNA from it?
Anna Petherick goes in search of some answers.
doi:10.1038/4541042a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F60EO
Natural selection: The evolution of cancer pp1046-1048
Cancer cells vary; they compete; the fittest survive.
Patrick Goymer reports on how evolutionary biology can be applied to
cancer — and what good it might do.
doi:10.1038/4541046a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F70EP
----------------------
CORRESPONDENCE
----------------------
Postdoc glut means academic pathway needs an overhaul p1049
Ian M. Brooks
doi:10.1038/4541049a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4F80EQ
Olympics may have a negative impact on China's research p1049
Yijun Chen and Nan Liu
doi:10.1038/4541049b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GA0Ea
Changes in the rules now governing Italy's drug industry p1049
Sergio Dompe
doi:10.1038/4541049c
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GB0Eb
Atheism could be science's contribution to religion p1049
Matthew Cobb and Jerry Coyne
doi:10.1038/4541049d
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GC0Ec
----------------------
BOOKS AND ARTS
----------------------
The blossoming of Japanese mathematics p1050
A new compilation of the illustrated geometry problems that decorated
shrines in seventeenth-century Japan provides puzzles that are still
intriguing today, finds Peter J. Lu.
Peter J. Lu reviews Sacred Mathematics: Japanese Temple Geometry by
Fukagawa Hidetoshi and Tony Rothman
doi:10.1038/4541050a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GD0Ed
The future ain't what it used to be p1051
Adam Rutherford reviews Future Proof/You Call This the Future? by
Nick Sagan, Mark Frary and Andy Walker
doi:10.1038/4541051a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GE0Ee
More cacophony than harmony pp1051-1052
John Carmody reviews The World In Six Songs: How the Musical Brain
Created Human Nature by Daniel J. Levitin
doi:10.1038/4541051b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GF0Ef
Culture dish p1052
doi:10.1038/4541052a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GG0Eg
Innovations of an ancient nation p1052
Jane Qiu reviews Chinese Memory: Treasures of a 5,000-year-old
Civilization
doi:10.1038/4541052b
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GH0Eh
Spartan sport laid bare p1053
Edgar Degas's painting of female athletes challenging male competitors
in classical Sparta raises subtle questions about gender, politics and
sport, explains Martin Kemp.
Martin Kemp
doi:10.1038/4541053a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GI0Ei
----------------------
ESSAY
----------------------
Battle of the sexes may set the brain pp1054-1055
A tug-of-war between the mother's and father's genes in the developing
brain could explain a spectrum of mental disorders from autism to
schizophrenia, suggest Christopher Badcock and Bernard Crespi.
Christopher Badcock and Bernard Crespi
doi:10.1038/4541054a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GJ0Ej
----------------------
NEWS AND VIEWS
----------------------
Human behaviour: Share and share alike pp1057-1058
The happy tendency to share resources equitably -- at least with
members of one's own social group -- is a central and unique
feature of human social life. It emerges, it seems, in middle
childhood.
Michael Tomasello and Felix Warneken
doi:10.1038/4541057a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GK0Ek
Earth science: A sheet-metal geodynamo pp1058-1059
A decade of modelling Earth's core on computers has led to the belief
that we understand what produces Earth's magnetic field. More
realistic simulations are now shaking that complacency.
Ulrich R. Christensen
doi:10.1038/4541058a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GL0El
Systems biology: Reverse engineering the cell pp1059-1062
Borrowing ideas that were originally developed to study electronic
circuits, two reports decipher how yeast reacts to changes in its
environment by analysing the organism's responses to oscillating
input signals.
Nicholas T. Ingolia and Jonathan S. Weissman
doi:10.1038/4541059a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GM0Em
50 & 100 Years Ago p1061
doi:10.1038/4541061a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GN0En
Condensed-matter physics: Dual realities in superconductors pp1062-1063
In some copper oxides, superconductivity emerges when fixed electrons
become mobile. A microscopy technique reveals that this process is
associated with the transfer of electrons between real and abstract
spaces.
Tetsuo Hanaguri
doi:10.1038/4541062a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GO0Eo
Developmental genetics: A sex-specific switch p1063
Tim Lincoln
doi:10.1038/4541063a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GP0Ep
----------------------
REVIEW
----------------------
Puzzles, promises and a cure for ageing pp1065-1071
Jan Vijg and Judith Campisi
doi:10.1038/nature07216
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GQ0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GR0Er
----------------------
ARTICLES
----------------------
How Cooper pairs vanish approaching the Mott insulator in
Bi2Sr2CaCu2O8+delta pp1072-1078
Y. Kohsaka et al.
doi:10.1038/nature07243
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GS0Es
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GT0Et
Egalitarianism in young children pp1079-1083
This paper presents evidence that young children's other regarding
preferences take a particular form -- inequality aversion -- that
develops between age 3 and 8. At age 3-4, most children behave
selfishly, whereas the vast majority at age 7–8 prefers resource
allocations that remove inequality. But if the removal of advantageous
inequality involves costly sharing, the egalitarian allocation is
chosen less often and the children tend to favour members of their own
social group.
Ernst Fehr, Helen Bernhard and Bettina Rockenbach
doi:10.1038/nature07155
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GU0Eu
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GV0Ev
Major viral impact on the functioning of benthic deep-sea
ecosystems pp1084-1087
Deep sea sediments contain large reservoirs of carbon in form of
microbial biomass, but the dynamics of this ecosystem are largely
unknown. Virus production is demonstrated to result in a significant
conversion of microbial biomass into labile carbon.
Roberto Danovaro et al.
doi:10.1038/nature07268
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GW0Ew
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GX0Ex
Misfolded proteins partition between two distinct quality control
compartments pp1088-1095
This study identifies two distinct quality control compartments in
yeast and mammalian cells. Paritioning of substrates to these
compartments is determined by their ubiquitination status and extent
of their aggregation. Misfolded proteins that are soluble and
ubquitinated accumulate in a juxtanuclear compartment, which is in
close proximity to proteasomes. In contrast, terminally aggregated
proteins such as prions and disease associated Huntingtin accumulate
in a perivacuolar inclusion.
Daniel Kaganovich, Ron Kopito and Judith Frydman
doi:10.1038/nature07195
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GY0Ey
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4GZ0Ez
----------------------
LETTERS
----------------------
A common mass scale for satellite galaxies of the Milky Way pp1096-1097
The Milky Way has at least 23 known satellite galaxies with
luminosities ranging from about a thousand to a billion times that of
the sun. This paper uses new measurements of the velocities of the
stars in these galaxies to show that they are consistent with them
having a common mass of about 107 times that of the Sun within their
central 300 parsecs. The faintest of the Milky Way satellites are
accordingly the most dark-matter-dominated galaxies known in the
Universe.
Louis E. Strigari et al.
doi:10.1038/nature07222
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ga0E7
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gb0E8
Experimental demonstration of a BDCZ quantum repeater node pp1098-1101
A building block of the BDCZ quantum repeater is realized,
demonstrating entanglement swapping with storage and retrieval of
light from atomic quantum memories.
Zhen-Sheng Yuan et al.
doi:10.1038/nature07241
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gc0EA
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gd0EB
Late Pliocene Greenland glaciation controlled by a decline in
atmospheric CO2 levels pp1102-1105
Use of a fully coupled atmosphere–ocean general circulation model and
an ice sheet model finds that Greenland glaciation is mainly
controlled by a decrease in atmospheric carbon dioxide levels from the
mid Pliocene to the Quaternary. In contrast, the model results suggest
that climatic shifts associated with other hypotheses are not large
enough to contribute significantly to the growth of the Greenland ice
sheet.
Daniel J. Lunt, Gavin L. Foster, Alan M. Haywood and Emma J. Stone
doi:10.1038/nature07223
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ge0EC
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gf0ED
Formation of current coils in geodynamo simulations pp1106-1109
Previously, the highest resolution geodynamo simulations were
performed at Ekman numbers down to 10 6, but this study made use of
4,096 processors of the Earth Simulator to produce a geodynamo
simulation with an Ekman number an order of magnitude smaller. It is
found that both the convective flow and magnetic field structures are
qualitatively different from lower resolution simulations, with
convection taking the form of sheet plumes or radial sheet jets.
Akira Kageyama, Takehiro Miyagoshi and Tetsuya Sato
doi:10.1038/nature07227
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gg0EE
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gh0EF
Acetylcholine contributes through muscarinic receptors to attentional
modulation in V1 p1110
Selective attention enhances both perceptual processing and neuronal
responses of sensory stimuli, but the cellular mechanisms of this
enhancement are not well understood. It is shown that iontophoretic
manipulation of acetylcholine in primary visual cortex enhances
attentionally modulated neuronal responses and behaviour while monkeys
are performing attentional tasks. The effect is specific to activation
of muscarinic receptors.
J. L. Herrero, M. J. Roberts, L. S. Delicato, M. A. Gieselmann,
P. Dayan & A. Thiele
doi:10.1038/nature07141
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gi0EG
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gj0EH
A blend of small molecules regulates both mating and development in
Caenorhabditis elegans p1115
A molecular social code promoting either mating or longevity has been
found in roundworms. A cocktail of chemicals from adult female
nematodes attracts males at low concentration, but signals
overcrowding and induces a dormant larval state at high
concentrations. The study challenges the general assumption that
different animal behaviours be modulated by distinct pheromones.
Jagan Srinivasan et al.
doi:10.1038/nature07168
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gk0EI
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gl0EJ
Metabolic gene regulation in a dynamically changing environment p1119
A microfluidics platform to present yeast cells with smoothly periodic
changes in culture conditions has been developed. It is observed that
the yeast metabolic system reliably responds to slowly changing
environment, but filters out fast fluctuations. It is then shown that
mutant cells that differed when probed in static environments have
actually been optimized for similarly robust responses to dynamically
changing environments.
Matthew R. Bennett et al.
doi:10.1038/nature07211
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gm0EK
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gn0EL
Crystal structure of the polymerase PAC–PB1N complex from an avian
influenza H5N1 virus p1123
Influenza A virus polymerase consists of three proteins, PA, PB1 and
PB2, and is critical for transcription and replication. This is one of
two papers detailing the crystal structure of the avian H5N1 PA C
terminal domain in complex with the PA binding domain of PB1.
Xiaojing He et al.
doi:10.1038/nature07120
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Go0EM
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gp0EN
The structural basis for an essential subunit interaction in influenza
virus RNA polymerase p1127
Influenza A virus polymerase consists of three proteins, PA, PB1 and
PB2, and is critical for transcription and replication. This is one of
two papers detailing the crystal structure of the avian H5N1 PA C
terminal domain in complex with the PA binding domain of PB1.
Eiji Obayashi et al.
doi:10.1038/nature07225
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gq0EO
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gr0EP
Multipotent somatic stem cells contribute to the stem cell niche in
the Drosophila testis p1132
Somatic stem cells in the Drosophila testis contribute to both the
apical hub and the somatic cyst cell lineage comprising the niche.
It is also shown that the transcriptional repressor escargot regulates
the ability of somatic cells to assume and/or maintain hub cell
identity.
Justin Voog, Cecilia D'Alterio & D. Leanne Jones
doi:10.1038/nature07173
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gs0EQ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gt0ER
Mouse development with a single E2F activator p1137
The E2F family is a family of proteins, some of which act as
transcription activators and others as repressors. It is shown that
E2f3a is sufficient to support mouse embryonic and postnatal
development. However, expression of E2f3b or E2f1 from the E2f3a locus
suppressed all the postnatal phenotypes associated with the
inactivation of E2f3a. It is concluded there is functional redundancy
among activators and that the requirement for E2f3a during postnatal
development is dictated by its regulatory sequences.
Shih-Yin Tsai et al.
doi:10.1038/nature07066
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gu0ES
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gv0ET
Cell-specific ATP7A transport sustains copper-dependent tyrosinase
activity in melanosomes p1142
Copper transport in the pigment forming cells, melanocytes is studied.
The enzyme tyrosinase catalyses melanin synthesis in melanosomes and
requires copper for its activity. It is reported that although
tyrosinase acquires copper within the TGN, it is inefficient and is
lost within intermediate trafficking vesicles. Tyrosinase is
subsequently reloaded with copper only when it reaches melanocytes
by the copper transporter ATP7A.
Subba Rao Gangi Setty, Danièle Tenza, Elena V. Sviderskaya,
Dorothy C. Bennett, Graça Raposo & Michael S. Marks
doi:10.1038/nature07163
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gw0EU
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gx0EV
----------------------
NATUREJOBS
----------------------
Prospect
Prospects p1147
How to rekindle your love affair with science.
Gene Russo
doi:10.1038/nj7208-1147a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4EM0Ek
----------------------
FUTURES
----------------------
Spamface p1150
Down in the jungle, something stirs.
Martin Hayes
doi:10.1038/4541150a
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Gy0EW
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27 August 2008
Structure of the guide-strand-containing argonaute silencing complex
Yanli Wang, Gang Sheng, Stefan Juranek, Thomas Tuschl
& Dinshaw J. Patel
doi:10.1038/nature07315
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lj0EM
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ll0EO
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
Qiao Zhou et al.
doi:10.1038/nature07314
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ln0EQ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lo0ER
Functional auditory hair cells produced in the mammalian cochlea by in
utero gene transfer
Samuel P. Gubbels et al.
doi:10.1038/nature07265
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lp0ES
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lq0ET
S-nitrosylation of histone deacetylase 2 induces chromatin remodelling
in neurons
Alexi Nott et al.
doi:10.1038/nature07238
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lr0EU
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ls0EV
A paracrine requirement for hedgehog signalling in cancer
Robert L. Yauch et al.
doi:10.1038/nature07275
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lt0EW
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lu0EX
24 August 2008
Identification of ALK as a major familial neuroblastoma predisposition
gene
Yael P. Mosse et al.
doi:10.1038/nature07261
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Lw0EZ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4Ly0Eb
TMEM16A confers receptor-activated calcium-dependent chloride
conductance
Young Duk Yang et al.
doi:10.1038/nature07313
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4L10EP
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4L30ER
Vancomycin-resistant enterococci exploit antibiotic-induced innate
immune deficits
Katharina Brandl et al.
doi:10.1038/nature07250
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4L50ET
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4L70EV
STING is an endoplasmic reticulum adaptor that facilitates innate
immune signalling
Hiroki Ishikawa and Glen N. Barber
doi:10.1038/nature07317
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4MA0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4MC0Ei
Regulatory networks define phenotypic classes of human stem cell lines
Franz-Josef Muller et al.
doi:10.1038/nature07213
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4ME0Ek
Article: http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B4MG0Em
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Journal of Perinatology presents
'Substance abuse treatment linked with
prenatal visits improves prenataloutcomes: a new standard'
An Early Start may mean a healthy beginning.
Introducing a new standard to healthy neonatal
development through early treatment programs.
Read the latest study online from Journal of Perinatology.
http://ealerts.nature.com/cgi-bin24/DM/y/enCf0Xztnp0HjB0B16K0EQ
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