21 August 2008 Volume 454 Number 7207, pp917-1028
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Submit an abstract now for the AACR's conference on
Frontiers in Cancer Prevention Research in Washington D.C.
Abstract Deadline: September 16, 2008.
Conference dates: November 16-19, 2008
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ZX0Ef
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NeuroPod is the neuroscience podcast from
Nature, produced in association with the
Dana Foundation. Each month, Kerri Smith
examines the latest research on the brain,
from its molecular makings to the mysteries
of the mind. In the July 2008 episode Kerri
delves into virtual reality drug dens, sleep
deprivation and false memories, electrical
harmony in the brain, and highlights
of the FENS meeting in Geneva.
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ZY0Eg
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0Bz7z0Ep
=====================================================================
Innovation
In the third of Nature's monthly commentary series on science
innovation, David Guston explains how policy can shape and steer
the mysterious and unpredictable innovation process.
Join in the discussion of this, a linked editorial,
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ZZ0Eh
And the previous two innovation commentaries on Nature Network
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Za0Eo
=====================================================================
----------------------
EDITORIALS
----------------------
Case not closed p917
The FBI says it has evidence showing that Bruce Ivins was behind the
2001 anthrax attacks -- but with his death, this will not be tested
in court. A full enquiry into the case is needed if justice is to
be done.
doi:10.1038/454917a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zb0Ep
Scandalous behaviour pp917-918
Austria's most serious report of scientific misconduct in recent
memory must be handled properly.
doi:10.1038/454917b
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zc0Eq
A case for nurture p918
Innovation is a complex ecosystem that requires careful cultivation.
doi:10.1038/454918a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ZZ0Eh
----------------------
RESEARCH HIGHLIGHTS
----------------------
Animal behaviour: Don't you step on my ... p920
doi:10.1038/454920a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zd0Er
Electrophysiology: On the pulse p920
doi:10.1038/454920b
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Ze0Es
Microbiology: Running on arsenic p920
doi:10.1038/454920c
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zf0Et
Fluid dynamics: Slip and slide p920
doi:10.1038/454920d
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zg0Eu
Atmospheric chemistry: Attacked from within p920
doi:10.1038/454920e
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zh0Ev
Climate indicators: Early birds pp920-921
doi:10.1038/454920f
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zi0Ew
Animal behaviour: Crowd control p921
doi:10.1038/454921a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zj0Ex
Immunology: The power of tick spit p921
doi:10.1038/454921b
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zk0Ey
Botany: Biofuel heir apparent? p921
doi:10.1038/454921c
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zl0Ez
Biophysics: Mob rule p921
doi:10.1038/454921d
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zm0E1
----------------------
JOURNAL CLUB
----------------------
Journal club p921
Michelle D. Wang
doi:10.1038/454921e
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zn0E2
----------------------
NEWS
----------------------
Report finds grave flaws in urology trial pp922-923
Scandal erupts at Austrian medical school.
Alison Abbott
doi:10.1038/454922a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zo0E3
Europe gets centres of excellence for neuroscience pp922-923
University College London will play host to £140-million institute.
Geoff Brumfiel
doi:10.1038/454922b
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zp0E4
Unproven stem-cell therapy ban p923
Bulgarian deputy minister quits over controversial treatment.
Maria Rossbauer
doi:10.1038/454923a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zq0E5
Whatever floats your boat pp924-925
Shipping is one of the most fuel-efficient ways to move freight, but
the industry still produces significant greenhouse-gas emissions,
including more than a quarter of the world's nitrogen oxides
emissions. And it also produces more sulphur dioxide emissions than
all land transportation combined. In the latest of our Future
Transport series, Duncan Graham-Rowe looks at the new wave in
shipping.
doi:10.1038/454924a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zr0E6
Bell Labs bottoms out p927
Institute pulls plug on basic research.
Geoff Brumfiel
doi:10.1038/454927a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zs0E7
FBI to reveal anthrax data p928
Science of case will be submitted to peer-reviewed journals.
Amber Dance
doi:10.1038/454928a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zt0E8
Leak leaves Antarctic observatory blinded p929
doi:10.1038/454929a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zu0EA
US ocean agency upgrades its research fleet p929
doi:10.1038/454929b
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zv0EB
Computer experts blast ruling to gag students p929
doi:10.1038/454929c
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zw0EC
Plans for the largest ever solar-power plants p929
doi:10.1038/454929d
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zx0ED
Science illustration course draws to an end p929
doi:10.1038/454929e
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zy0EE
New species of robin found in Gabon p929
doi:10.1038/454929f
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Zz0EF
Correction p929
doi:10.1038/454929g
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z10E1
----------------------
NEWS FEATURES
----------------------
Volcanology: Fire and life pp930-932
Recent eruptions and field expeditions may herald a return to glory
for the Son of Krakatau. Jerry Guo explores what the 78-year-old
island has to offer.
doi:10.1038/454930a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z20E2
Neuroscience: The great squid hunt pp934-936
When jumbo Humboldt squid disappeared from Chilean waters, it led to
the demise of a world-class electrophysiology laboratory. Now the
creatures are back, finds Tony Scully, and so are the scientists.
doi:10.1038/454934a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z30E3
----------------------
CORRESPONDENCE
----------------------
IVF: stars may have to consider the risk of stolen parenthood p938
Christoph Bock
doi:10.1038/454938a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z40E4
IVF: tight regulation may not be suitable for all cultures p938
David Adamson
doi:10.1038/454938b
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z50E5
A possible way out of the impact-factor game pp938-939
Herman Tse
doi:10.1038/454938c
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z60E6
The human face of a difficult, heroic, passionate scientist p939
Elof Axel Carlson
doi:10.1038/454939a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z70E7
Micromanaging ideas risks impeding flow of potential benefits p939
Jim Woodgett
doi:10.1038/454939b
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3Z80E8
Open debate could slow flu vaccine production p939
Stephen Inglis, John Wood and Philip Minor
doi:10.1038/454939c
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aA0EP
----------------------
COMMENTARY
----------------------
Innovation policy: not just a jumbo shrimp pp940-941
Policies that predict and direct innovative research might seem to be
a practical impossibility, says David H. Guston, but social sciences
point to a solution.
doi:10.1038/454940a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aB0EQ
----------------------
BOOKS AND ARTS
----------------------
Flat Earth and Amazons pp942-943
Charles-Marie de La Condamine's quest to Peru to calculate Earth's
flattened shape included some adventures that didn't make it into the
offical records at the time, finds D. Graham Burnett.
D. Graham Burnett reviews Measuring the New World: Enlightenment
Science and South America by Neil Safier
doi:10.1038/454942a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aC0ER
Microbial fuels for the future pp943-944
Bruce Logan reviews Bioenergy
doi:10.1038/454943a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aD0ES
A potter round Darwin's patch pp944-945
Beverley Glover reviews Darwin's Garden: Down House and The Origin of
Species by Michael Boulter
doi:10.1038/454944a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aE0ET
Exhibition digs deep to save our soils p946
Amber Dance reviews Dig It! The Secrets of Soil
doi:10.1038/454946a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aF0EU
----------------------
NEWS AND VIEWS
----------------------
Developmental biology: Neither fat nor flesh pp947-948
In mammals, white adipose tissue stores fat, whereas brown adipose
tissue burns fat. Brown adipocytes have a common origin with muscle
cells, which could help explain their unusual function.
Barbara Cannon and Jan Nedergaard
doi:10.1038/454947a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aG0EV
Chemistry: Precious little catalyst pp948-949
In gold catalysis, less is more. Bulk gold is an inert metal, but
tiny particles containing as few as 55 gold atoms are effective at
catalysing the targeted oxidation of hydrocarbons.
D. Wayne Goodman
doi:10.1038/454948a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aH0EW
Physiology: Mutant flies lack magnetic sense pp949-951
It seems that fruitflies can detect magnetic fields, but only if
they are illuminated with blue light. Mutant flies reveal that a
light-responsive receptor underpins this peculiar behaviour.
Francois Rouyer
doi:10.1038/454949a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aI0EX
50 & 100 years ago p950
doi:10.1038/454950a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aJ0EY
Materials science: A metal left spinning pp951-952
Conductors and semiconductors usually behave like conduits for fluids
of electrons. But sometimes the electrons' spins conspire to produce
unconventional behaviours that can be turned off and on with magnets.
Zachary Fisk and Stephan von Molnar
doi:10.1038/454951a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aK0EZ
Biogeochemistry: Who lives in the sea floor? pp952-953
The sediments that blanket the sea floor contain tremendous numbers of
microorganisms. This deep marine biosphere, which is probed by deep-sea
drilling, is a new frontier for microbiologists and geochemists.
Ann Pearson
doi:10.1038/454952a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aL0Ea
Archaeology: An oasis in time p953
Christopher Surridge
doi:10.1038/454953a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aM0Eb
Obituary: Yoji Totsuka (1942-2008) p954
Leader in the discovery of neutrino oscillations.
Henry W. Sobel and Yoichiro Suzuki
doi:10.1038/454954a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aN0Ec
----------------------
ARTICLES
----------------------
The Trichoplax genome and the nature of placozoans pp955-960
The genome sequence for Trichoplax adhaerens is analysed, and it is
reported that the organism retains many features of the last common
ancestor with cnidarians and bilaterians, estimated to be over 600
million years ago. However, T. adhaerens also contains genes for
developmental patterns and cell types which have never been seen in
this animal, suggesting that we might still not know the full story.
Mansi Srivastava et al.
doi:10.1038/nature07191
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aO0Ed
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aP0Ee
PRDM16 controls a brown fat/skeletal muscle switch pp961-967
Brown fat can increase energy expenditure and thus may protect against
obesity. Here it is shown that brown but not white fat cells arise
from precursors that express a marker that thus far has only been
found in muscle cells. In addition, loss of the transcriptional
regulator PRDM16 from brown fat precursors causes a loss of brown fat
characteristics and promotes muscle differentiation.
Patrick Seale et al.
doi:10.1038/nature07182
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aQ0Ef
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aR0Eg
----------------------
LETTERS
----------------------
Magnetic support of the optical emission line filaments in NGC 1275 pp968-970
The giant elliptical galaxy NGC 1275 is surrounded by a giant
nebulosity of emission line filaments, which are more than 108 yr old.
The mechanism by which the filaments are stabilized against tidal
shear and dissipation into the surrounding 4×107 K gas has been
unclear. This paper reports observations that resolve thread like
structures in the filaments and concludes that magnetic fields in the
threads, in pressure balance with the surrounding gas, stabilize the
filaments.
A. C. Fabian et al.
doi:10.1038/nature07169
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aS0Eh
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aT0Ei
Heterogeneous chemistry in the atmosphere of Mars pp971-975
A state of the art general circulation model is used along with new
observations of the Martian ozone layer to show that model simulations
that include chemical reactions occurring on ice clouds result in much
improved quantitative agreement with observed Martian ozone levels
compared to model simulations based on gas phase chemistry alone.
Ozone is readily destroyed by hydrogen radicals and is therefore a
sensitive tracer of the chemistry that regulates the atmosphere of
Mars. The results suggest that heterogeneous chemistry on ice clouds
plays an important role in controlling the stability and composition
of the Martian atmosphere.
Franck Lefevre et al.
doi:10.1038/nature07116
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aU0Ej
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aV0Ek
Doping a semiconductor to create an unconventional metal pp976-980
This paper reports an intriguing class of materials -- silicon based
semiconductor compounds near a metal insulator transition -- that can
also display a non Fermi liquid state, and which can be switched off
by a modest magnetic field functions. The system can be unambiguously
explained with a non Fermi liquid model, and it is suggested that a
physical realization of the only mathematically rigorous route to a
non Fermi liquid might have been found.
N. Manyala, J. F. DiTusa, G. Aeppli and A. P. Ramirez
doi:10.1038/nature07137
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aW0El
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aX0Em
Selective oxidation with dioxygen by gold nanoparticle catalysts
derived from 55-atom clusters pp981-983
Although fairly inert in its bulk form, Gold exhibits remarkable
catalytic activity when employed in the form of nanoparticles with a
size below ~3.5 nm. 55 atom clusters are used to deposit 1.4 nm gold
particles on inert support materials, it is shown that these catalyse
the oxidation of styrene by O2, whereas larger gold particles are
completely inactive. This suggests that catalytic activity arises from
the altered electronic structure intrinsic to small gold nanoparticles.
Mark Turner et al.
doi:10.1038/nature07194
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aY0En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aZ0Eo
Effect of phase transitions on compressional-wave velocities in the
Earth's mantle pp984-986
Synchrotron based experimental data demonstrates softening of the bulk
modulus within the two phase loop of olivine–ringwoodite at a time
scale of 100 s. It is found that by scaling the amplitude of the
pressure perturbation and grain size to those expected in the Earth,
the compressional wave velocities within the discontinuities at 410,
520 and possibly 660 km depth are likely to be significantly lower
than otherwise expected.
Li Li and Donald J. Weidner
doi:10.1038/nature07230
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aa0Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ab0Ew
Self-destructive cooperation mediated by phenotypic noise pp987-990
It is observed that the expression of virulence factors varies between
clonal cells of the pathogenic bacterium Salmonella tythimurium.
Phenotypic noise leads to a differentiation into two subpopulations of
Salmonella that work together to establish an infection. This involves
apparent self destructive cooperation, in which individuals sacrifice
themselves for the benefit of others.
Martin Ackermann et al.
doi:10.1038/nature07067
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ac0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ad0Ey
Significant contribution of Archaea to extant biomass in marine
subsurface sediments p991
The marine subsurface is a vast reservoir of microbial biomass, but
whether Archaea or Bacteria are the major players has been the subject
of much debate. Using a variety of methods it is now demonstrated that
Archaea dominate this ecosystem.
Julius S. Lipp, Yuki Morono, Fumio Inagaki & Kai-Uwe Hinrichs
doi:10.1038/nature07174
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ae0Ez
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3af0E1
Spatio-temporal correlations and visual signalling in a complete
neuronal population p995
The functional significance of correlated firing in a complete
population of macaque parasol retinal ganglion cells using a model of
multi-neuron spike responses is analysed. Fitting the physiological
data to a model of multi neuron spike responses, it is found that a
significant fraction of what is usually considered single cell noise
in trial to trial response variability can be explained by
correlations, and that a significant amount of sensory information can
be decoded from the correlation structure.
Jonathan W. Pillow et al.
doi:10.1038/nature07140
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ag0E2
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ah0E3
New role of bone morphogenetic protein 7 in brown adipogenesis and
energy expenditure pp1000-1004
A member of the family of bone morphogenetic proteins, BMP 7, promotes
the differentiation of brown, not white, fat cells. BMP 7 switches on
regulators of brown fat, among which there is PRDM16, adipogenic
transcription factors, and mitochondrial biogenesis. BMP 7 can
persuade mesenchymal progenitor cells to become brown adipocytes.
Without BMP 7 less brown fat develops.
Yu-Hua Tseng et al.
doi:10.1038/nature07221
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ai0E4
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aj0E5
The pathogen protein EspFU hijacks actin polymerization using mimicry
and multivalency p1005
One of two related papers that elucidates the mechanism by which EspFU
activates the host actin machinery. A biochemical analysis shows that
EspFU activates the host WASP (Wiscott Aldrich syndrome protein)
family of actin nucleating factors, which are normally activated by
the GTPase, Cdc42.
Nathan A. Sallee et al.
doi:10.1038/nature07170
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ak0E6
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3al0E7
Structural mechanism of WASP activation by the enterohaemorrhagic
E. coli effector EspFU p1009
One of two related papers that elucidates the mechanism by which EspFU
activates the host actin machinery This paper uses a structural
approach to provide details of the binding interaction between EspFU
and N WASP and activation. EspFU mimics an autoinhibitory element
found within N WASP to induce its activation resulting in actin
assembly. This mechanism ensures that EspFu specifically activates
WASP and not a broad spectrum of Cdc42 targets.
Hui-Chun Cheng, Brian M. Skehan, Kenneth G. Campellone, John M. Leong
& Michael K. Rosen
doi:10.1038/nature07160
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3am0E8
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3an0EA
Cryptochrome mediates light-dependent magnetosensitivity in
Drosophila p1014
Animals are able to navigate by means of the Earth's magnetic field,
but how they detect geomagnetic fields has been a matter of debate.
It shown that Drosophila use the blue light photoreceptor,
cryptochrome, to achieve magnetosensitivity, independent of its
function in the circadian clock.
Robert J. Gegear, Amy Casselman, Scott Waddell & Steven M. Reppert
doi:10.1038/nature07183
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ao0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ap0EC
Molecular basis of the copulatory plug polymorphism in Caenorhabditis
elegans p1019
The nematode Caenorhabditis elegans has been a genetic model system
for many years, but this paper is the first to identify a gene behind
a classic polymorphism in these organisms. Some strains of males
deposit a gelatinous plug in the female after mating, and others
don't. This is due to changes in a single gene encoding a mucin like
gene, and this change was able to spread through C. elegans
populations around the world.
Michael F. Palopoli et al.
doi:10.1038/nature07171
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aq0ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ar0EE
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NATUREJOBS
----------------------
Prospect
Prospects p1023
Seeking a new kind of graduate school rankings scheme.
Gene Russo
doi:10.1038/nj7207-1023a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3as0EF
Special Report
Dissension in the ranks p1024
Graduate programmes are rated by various organizations using different
criteria. How much use are these rankings?
Genevive Bjorn surveys the options.
doi:10.1038/nj7207-1024a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3at0EG
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FUTURES
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All of me p1028
A man walks into a bar ...
Ed Rybicki
doi:10.1038/4541028a
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3au0EH
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ADVANCE ONLINE PUBLICATION
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20 August 2008
Article
Structural insights into the evolutionary paths of oxylipin
biosynthetic enzymes
Dong-Sun Lee, Pierre Nioche, Mats Hamberg & C. S. Raman
doi:10.1038/nature07307
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3av0EI
Letters
ATP drives lamina propria TH17 cell differentiation
Koji Atarashi et al.
doi:10.1038/nature07240
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3aw0EJ
CDK targets Sae2 to control DNA-end resection and homologous
recombination
Pablo Huertas, Felipe Cortés-Ledesma, Alessandro A. Sartori,
Andrés Aguilera & Stephen P. Jackson
doi:10.1038/nature07215
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ax0EK
The deubiquitinylation and localization of PTEN are regulated by a
HAUSP–PML network
Min Sup Song et al.
doi:10.1038/nature07290
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3ay0EL
Counterintuitive carbon-to-nutrient coupling in an Arctic pelagic
ecosystem
T. F. Thingstad et al.
doi:10.1038/nature07235
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3az0EM
17 August 2008
Article
An intrinsic mechanism of corticogenesis from embryonic stem cells
Nicolas Gaspard et al.
doi:10.1038/nature07287
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3a10E8
Letters
Replication fork movement sets chromatin loop size and origin choice
in mammalian cells
Sylvain Courbet et al.
doi:10.1038/nature07233
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3a20EA
Modelling Myc inhibition as a cancer therapy
Laura Soucek et al.
doi:10.1038/nature07260
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3a30EB
Heterochromatin links to centromeric protection by recruiting
shugoshin
Yuya Yamagishi, Takeshi Sakuno, Mari Shimura & Yoshinori Watanabe
doi:10.1038/nature07217
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3a40EC
Neutralizing antibodies derived from the B cells of 1918 influenza
pandemic survivors
Xiaocong Yu et al.
doi:10.1038/nature07231
http://ealerts.nature.com/cgi-bin24/DM/y/em3S0Xztnp0HjB0B3IP0EG
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