July 2008 Volume 22 Number 7, pp 1299 - 1474
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Web Focus and Special Feature on Dendritic Cells
brought to you by Immunology & Cell Biology
Featuring a collection of research and review articles on the latest
understanding of DC heterogeneity, this web focus also dives into the
realm of T cell responses and functional diversity. The accompanying
two-part special feature highlights the gaps in the understanding and
potential this holds for the future.
Access the Web Focus and Special Feature on Dendritic Cells to view
select articles FREE of charge!
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20ByhI0EV
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To read the full Guide to Authors for Leukemia, visit
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SPOTLIGHT REVIEWS
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Clinical correlates of JAK2V617F presence or allele burden in
myeloproliferative neoplasms: a critical reappraisal
A M Vannucchi, E Antonioli, P Guglielmelli, A Pardanani and A Tefferi
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzto0EM
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztp0EN
The myelodysplastic//myeloproliferative neoplasms: myeloproliferative
diseases with dysplastic features
A Orazi and U Germing
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztq0EO
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztr0EP
Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in
myeloproliferative disorders
C Walz, N C P Cross, R A Van Etten and A Reiter
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzts0EQ
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztt0ER
Juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia
P D Emanuel
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztu0ES
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztv0ET
Treatment of plasma cell dyscrasias with lenalidomide
M A Dimopoulos, E Kastritis and S V Rajkumar
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztw0EU
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztx0EV
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ORIGINAL ARTICLES
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Bruton's tyrosine kinase is not essential for Bcr-Abl-mediated
transformation of lymphoid or myeloid cells
M MacPartlin, A M Smith, B J Druker, L A Honigberg and M W Deininger
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzty0EW
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bztz0EX
Is BAL useful in patients with acute myeloid leukemia admitted in ICU
for severe respiratory complications?
A Rabbat, D Chaoui, A Lefebvre, N Roche, O Legrand, C Lorut, B Rio,
J-P Marie and G Huchon
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt10EK
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt20EL
Gene expression profiling distinguishes JAK2V617F-negative from
JAK2V617F-positive patients in essential thrombocythemia
E Puigdecanet, B Espinet, J J Lozano, L Sumoy, B Bellosillo, L
Arenillas, A Alvarez-Larran, F Sole, S Serrano, C Besses and L
Florensa
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt30EM
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt40EN
Quantitative MRD monitoring identifies distinct GVL response patterns
after allogeneic stem cell transplantation for chronic lymphocytic
leukemia: results from the GCLLSG CLL3X trial
M Ritgen, S Bottcher, S Stilgenbauer, D Bunjes, J Schubert, S Cohen, A
Humpe, M Hallek, M Kneba, N Schmitz, H Dohner and P Dreger
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt50EO
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt60EP
HLA-DP as specific target for cellular immunotherapy in HLA class
II-expressing B-cell leukemia
C E Rutten, S A P van Luxemburg-Heijs, M Griffioen, E W A Marijt, I
Jedema, M H M Heemskerk, E F M Posthuma, R Willemze and J H F
Falkenburg
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt70EQ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Bzt80ER
Resistance to FLT3 inhibition in an in vitro model of primary AML
cells with a stem cell phenotype in a defined microenvironment
U Mony, M Jawad, C Seedhouse, N Russell and M Pallis
Abstract:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuA0Eb
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuB0Ec
Disruption of the Bcr-Abl//Hsp90 protein complex: a possible mechanism
to inhibit Bcr-Abl-positive human leukemic blasts by novobiocin
L X Wu, J H Xu, K Z Zhang, Q Lin, X W Huang, C X Wen and Y Z Chen
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuC0Ed
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuD0Ee
Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and
in vivo
M A Shammas, H Koley, R C Bertheau, P Neri, M Fulciniti, P Tassone, S
Blotta, A Protopopov, C Mitsiades, R B Batchu, K C Anderson, A Chin, S
Gryaznov and N C Munshi
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuE0Ef
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuF0Eg
VTD combination therapy with bortezomib-thalidomide-dexamethasone is
highly effective in advanced and refractory multiple myeloma
M Pineda-Roman, M Zangari, F van Rhee, E Anaissie, J Szymonifka, A
Hoering, N Petty, J Crowley, J Shaughnessy, J Epstein and B Barlogie
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuG0Eh
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuH0Ei
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LETTERS TO THE EDITOR
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Myeloid leukemia in children 4 years or older with Down syndrome often
lacks GATA1 mutation and cytogenetics and risk of relapse are more
akin to sporadic AML
H Hasle, J Abrahamsson, M Arola, A Karow, A O'Marcaigh, D Reinhardt, D
K H Webb, E van Wering, B Zeller, C M Zwaan and P Vyas
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuI0Ej
Sirolimus enhances the effect of apoptotic cell infusion on
hematopoietic engraftment and tolerance induction
F Bonnefoy, E Masson, S Perruche, A Marandin, C Borg, A Radlovic, B
Shipman, P Tiberghien, P Saas and F Kleinclauss
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuJ0Ek
Monoallelic or biallelic LMO2 expression in relation to the LMO2
rearrangement status in pediatric T-cell acute lymphoblastic leukemia
P Van Vlierberghe, H B Beverloo, J Buijs-Gladdines, E R van Wering, M
Horstmann, R Pieters and J P P Meijerink
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuK0El
Induction of Toll-like receptor 2 and 4 expression on CD4+ and CD8+ T
cells in G-CSF-mobilized unrelated peripheral blood stem cell grafts
during leukapheresis: impact on patient outcome
U Platzbecker, J Stoehlmacher, C Pabst, E Goekkurt, U Oelschlagel, H
Schirutschke, K Holig, C Theuser, U Mogck, G Ehninger and M Bornhauser
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuL0Em
MicroRNA expression in lymphocyte development and malignancy
C H Lawrie, N J Saunders, S Soneji, S Palazzo, H M Dunlop, C D O
Cooper, P J Brown, X Troussard, H Mossafa, T Enver, F Pezzella, J
Boultwood, J S Wainscoat and C S R Hatton
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuM0En
Lymphocyte subpopulation imbalances, bone marrow hematopoiesis and
histopathology in rituximab-treated lymphoma patients with late-onset
neutropenia
K Stamatopoulos, T Papadaki, C Pontikoglou, I Athanasiadou, N
Stavroyianni, J Bux, I Batsis, K Pyrovolaki, G Paterakis, D
Anagnostou, A Anagnostopoulos and H A Papadaki
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuN0Eo
Inhibition of MEK//ERK signaling synergistically potentiates histone
deacetylase inhibitor-induced growth arrest, apoptosis and acetylation
of histone H3 on p21waf1 promoter in acute myelogenous leukemia cell
C Nishioka, T Ikezoe, J Yang, H P Koeffler and A Yokoyama
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuO0Ep
Tandutinib inhibits FMS receptor signalling, and macrophage and
osteoclast formation in vitro
N Brownlow, M Vaid and N J Dibb
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuP0Eq
JAK2V617F-positive polycythemia vera and Philadelphia
chromosome-positive chronic myeloid leukemia: one patient with two
distinct myeloproliferative disorders
N Cambier, A Renneville, T Cazaentre, V Soenen, C Cossement, S
Giraudier, N Grardel, J-L Lai, C Rose and C Preudhomme
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuQ0Er
A novel functional assay using etoposide plus nutlin-3a detects and
distinguishes between ATM and TP53 mutations in CLL
O G Best, A C Gardiner, A Majid, R Walewska, B Austen, A Skowronska, R
Ibbotson, T Stankovic, M J S Dyer and D G Oscier
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuR0Es
NPM1-mutated acute myeloid leukaemia occurring in JAK2-V617F+ primary
myelofibrosis: de-novo origin?
L Pasqualucci, S Li, G Meloni, S Schnittger, S Gattenlohner, A Liso, M
Di Ianni, M P Martelli, E Pescarmona, R Foa, T Haferlach, R C Skoda
and B Falini
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuS0Et
Two cases of hypereosinophilia and high-risk acute lymphoblastic
leukemia
R Sutton, M Lonergan, H Tapp, N C Venn, M Haber, M D Norris, T A
O'Brien, F Alvaro and T Revesz
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuT0Eu
Preclinical targeting of NF-[kappa]B and FLT3 pathways in AML cells
E Griessinger, C Frelin, N Cuburu, V Imbert, C Dageville, M
Hummelsberger, N Sirvent, M Dreano and J-F Peyron
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuU0Ev
Genomic and molecular switching in relapsed acute promyelocytic
leukemia
F Albano, A Pannunzio, L Anelli, A Zagaria, V Liso, M Rocchi and G
Specchia
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuV0Ew
Evidence suggesting the presence of a stem cell clone anteceding the
acquisition of the JAK2-V617F mutation
R Jamal, C Belisle, M-C Lessard, J Hebert, D-C Roy, R Levine and L
Busque
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20BzuW0Ex
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Laboratory Investigation presents:
"Understanding the development of human bladder cancer by using a
whole-organ genomic mapping strategy"
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20ByIM0E3
Can this disease be detected earlier? Genome-wide mapping of human
bladder cancer has identified key genetic risk areas for cancer
development and provides new insight into early genetic origins of
cancer. View the complete article
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20ByIM0E3
online at Laboratory Investigation
http://ealerts.nature.com/cgi-bin24/DM/y/emLt0Xztnp0Hi20Fnv0EP .
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